FNab03971

antibody from FineTest Biotech

Targeting: HORMAD1 CT46, DKFZP434A1315

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Validation data

Product number: FNab03971 - Provider product page
Provider: FineTest Biotech
Product name: HORMAD1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Plays a key role in meiotic progression. Regulates 3 different functions during meiosis: ensures that sufficient numbers of processed DNA double-strand breaks(DSBs) are available for successful homology search by increasing the steady-state numbers of single-stranded DSB ends. Promotes synaptonemal-complex formation independently of its role in homology search. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin(MSUC) and meiotic prophase quality control in both sexes(By similarity).
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: HORMA domain containing 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

HORMAD1 protein structure - FNab03971 shown in red.