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- References [71]
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- Product number
- 11239-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11239-1-AP, RRID:AB_2245581
- Product name
- Cathepsin K antibody
- Antibody type
- Polyclonal
- Description
- Cathepsin K antibody (Cat. #11239-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references VSIG4 inhibits RANKL-induced osteoclastogenesis by enhancing Nrf2-dependent antioxidant response against reactive oxygen species production.
Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis.
MEDAG expression in vitro and paeoniflorin alleviates bone loss by regulating the MEDAG/AMPK/PPARγ signaling pathway in vivo.
Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis.
Isoquercitrin attenuates the osteoclast-mediated bone loss in rheumatoid arthritis via the Nrf2/ROS/NF-κB pathway.
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Nel-like Molecule Type 1 Combined with Gold Nanoparticles Modulates Macrophage Polarization, Osteoclastogenesis, and Oral Microbiota in Periodontitis.
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
A parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
Isopsoralen suppresses receptor activator of nuclear factor kappa-β ligand-induced osteoclastogenesis by inhibiting the NF-κB signaling.
The genetic background determines material-induced bone formation through the macrophage-osteoclast axis.
Evidence that pyrophosphate acts as an extracellular signalling molecule to exert direct functional effects in primary cultures of osteoblasts and osteoclasts.
Hypoxia Drives Material-Induced Heterotopic Bone Formation by Enhancing Osteoclastogenesis via M2/Lipid-Loaded Macrophage Axis.
Effect of mitophagy in the formation of osteomorphs derived from osteoclasts.
Long noncoding RNA Malat1 inhibits Tead3-Nfatc1-mediated osteoclastogenesis to suppress osteoporosis and bone metastasis.
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing.
Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment.
Babam2 negatively regulates osteoclastogenesis by interacting with Hey1 to inhibit Nfatc1 transcription.
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
Extracellular Vesicles Derived From Murine Cementoblasts Possess the Potential to Increase Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastogenesis.
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption.
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase : a novel approach in the prevention of osteoclastogenesis.
Effects of urolithin A on osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand via bone morphogenic protein 2.
Sickle cell disease promotes sex-dependent pathological bone loss through enhanced cathepsin proteolytic activity in mice.
Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles.
Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway.
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Mechanical loading attenuates breast cancer-associated bone metastasis in obese mice by regulating the bone marrow microenvironment.
Andrographolide prevents bone loss via targeting estrogen-related receptor-α-regulated metabolic adaption of osteoclastogenesis.
Interleukin-1 induces receptor activator of nuclear factor-κB ligand-independent osteoclast differentiation in RAW264.7 cells.
BMP2 immune complexes promote new bone formation by facilitating the direct contact between osteoclasts and osteoblasts.
4-Hexylresorcinol inhibits osteoclastogenesis by suppressing the NF-κB signaling pathway and reverses bone loss in ovariectomized mice.
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
PERK controls bone homeostasis through the regulation of osteoclast differentiation and function.
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Circadian control of the secretory pathway maintains collagen homeostasis.
Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway.
Cysteine cathepsins are altered by flow within an engineered in vitro microvascular niche.
ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth.
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis.
miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway.
Ankle loading ameliorates bone loss from breast cancer-associated bone metastasis.
Treadmill Running in Established Phase Arthritis Inhibits Joint Destruction in Rat Rheumatoid Arthritis Models.
Low‑frequency pulsed electromagnetic field inhibits RANKL‑induced osteoclastic differentiation in RAW264.7 cells by scavenging reactive oxygen species.
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis.
Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo.
Constitutive Activation of β-Catenin in Differentiated Osteoclasts Induces Bone Loss in Mice.
Simvastatin improves oral implant osseointegration via enhanced autophagy and osteogenesis of BMSCs and inhibited osteoclast activity.
YAP1 is essential for osteoclastogenesis through a TEADs-dependent mechanism.
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca(2+)-calcineurin-NFATc1 signaling pathway.
Cathepsin K in Lymphangioleiomyomatosis: LAM Cell-Fibroblast Interactions Enhance Protease Activity by Extracellular Acidification.
Role of endoplasmic reticulum stress in disuse osteoporosis.
Increased expression and activation of cathepsin K in human osteoarthritic cartilage and synovial tissues.
Expression profile of cathepsins indicates the potential of cathepsins B and D as prognostic factors in breast cancer patients.
Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity.
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Dental Abnormalities Caused by Novel Compound Heterozygous CTSK Mutations.
Bone histomorphometry in a long-term hemodialysis patient with hypoparathyroidism and sarcoidosis.
Lentiviral small hairpin RNA knockdown of macrophage inflammatory protein-1γ ameliorates experimentally induced osteoarthritis in mice.
Hyaluronan inhibits TLR-4 dependent cathepsin K and matrix metalloproteinase 1 expression in human fibroblasts.
Osteoarthritic change is delayed in a Ctsk-knockout mouse model of osteoarthritis.
Cholesteatoma growth and proliferation: relevance with serpin B3.
Antifibrotic effects of curcumin are associated with overexpression of cathepsins K and L in bleomycin treated mice and human fibroblasts.
Co-opting endogenous immunoglobulin for the regulation of inflammation and osteoclastogenesis in humans and mice.
Miao J, Tu Y, Jiang J, Ren R, Wu Q, Liang H, Wang T, Lin B, Wu J, Pan Y, Wang X, Jin H
International journal of biological macromolecules 2024 Mar;260(Pt 2):129357
International journal of biological macromolecules 2024 Mar;260(Pt 2):129357
Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis.
Zhao Y, Ning J, Teng H, Deng Y, Sheldon M, Shi L, Martinez C, Zhang J, Tian A, Sun Y, Nakagawa S, Yao F, Wang H, Ma L
Nature communications 2024 Mar 16;15(1):2384
Nature communications 2024 Mar 16;15(1):2384
MEDAG expression in vitro and paeoniflorin alleviates bone loss by regulating the MEDAG/AMPK/PPARγ signaling pathway in vivo.
Liu H, Chang Z, Liu S, Zhu R, Ma J, Lu X, Li L, Zhang Z
Heliyon 2024 Jan 15;10(1):e24241
Heliyon 2024 Jan 15;10(1):e24241
Age-related decline in melatonin contributes to enhanced osteoclastogenesis via disruption of redox homeostasis.
Wu DZ, Zhu GZ, Zhao K, Gao JW, Cai GX, Li HZ, Huang YS, Tu C, Zhuang JS, Huang ZW, Zhong ZM
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10
Molecular medicine (Cambridge, Mass.) 2024 Jan 12;30(1):10
Isoquercitrin attenuates the osteoclast-mediated bone loss in rheumatoid arthritis via the Nrf2/ROS/NF-κB pathway.
Liu Y, Li TQ, Bai J, Liu WL, Wang ZR, Feng C, Pu LL, Wang XX, Liu H
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166977
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166977
Three Birds, One Stone: An Osteo-Microenvironment Stage-Regulative Scaffold for Bone Defect Repair through Modulating Early Osteo-Immunomodulation, Middle Neovascularization, and Later Osteogenesis.
Yuan Y, Xu Y, Mao Y, Liu H, Ou M, Lin Z, Zhao R, Long H, Cheng L, Sun B, Zhao S, Zeng M, Lu B, Lu H, Zhu Y, Chen C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(6):e2306428
Nel-like Molecule Type 1 Combined with Gold Nanoparticles Modulates Macrophage Polarization, Osteoclastogenesis, and Oral Microbiota in Periodontitis.
Liao W, Ni C, Ge R, Li Y, Jiang S, Yang W, Yan F
ACS applied materials & interfaces 2024 Feb 21;16(7):8442-8458
ACS applied materials & interfaces 2024 Feb 21;16(7):8442-8458
Yunnan Baiyao Inhibits Periodontitis by Suppressing the Autophagic Flux.
Li Y, Liu W, Zhao R, An Y, Zhang M, Ren X, He H
International dental journal 2024 Apr;74(2):284-293
International dental journal 2024 Apr;74(2):284-293
A parathyroid hormone related supramolecular peptide for multi-functionalized osteoregeneration.
Hao Z, Feng Q, Wang Y, Wang Y, Li H, Hu Y, Chen T, Wang J, Chen R, Lv X, Yang Z, Chen J, Guo X, Li J
Bioactive materials 2024 Apr;34:181-203
Bioactive materials 2024 Apr;34:181-203
Isopsoralen suppresses receptor activator of nuclear factor kappa-β ligand-induced osteoclastogenesis by inhibiting the NF-κB signaling.
Zhan W, Ruan B, Dong H, Wang C, Wu S, Yu H, Xu X, Sun H, Cai J
PeerJ 2023;11:e14560
PeerJ 2023;11:e14560
The genetic background determines material-induced bone formation through the macrophage-osteoclast axis.
Li M, Li D, Jiang Y, He P, Li Y, Wu Y, Lei W, de Bruijn JD, Cannon RD, Mei L, Zhang H, Ji P, Zhang H, Yuan H
Biomaterials 2023 Nov;302:122356
Biomaterials 2023 Nov;302:122356
Evidence that pyrophosphate acts as an extracellular signalling molecule to exert direct functional effects in primary cultures of osteoblasts and osteoclasts.
Bourne LE, Davies BK, Millan JL, Arnett TR, Wheeler-Jones CPD, Keen JAC, Roberts SJ, Orriss IR
Bone 2023 Nov;176:116868
Bone 2023 Nov;176:116868
Hypoxia Drives Material-Induced Heterotopic Bone Formation by Enhancing Osteoclastogenesis via M2/Lipid-Loaded Macrophage Axis.
Li D, Jiang Y, He P, Li Y, Wu Y, Lei W, Liu N, de Bruijn JD, Zhang H, Zhang H, Ji P, Yuan H, Li M
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(15):e2207224
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 May;10(15):e2207224
Effect of mitophagy in the formation of osteomorphs derived from osteoclasts.
Huang T, Wang Y, Yu Z, Miao X, Jiang Z, Yu K, Fu M, Lai K, Wang Y, Yang G
iScience 2023 May 19;26(5):106682
iScience 2023 May 19;26(5):106682
Long noncoding RNA Malat1 inhibits Tead3-Nfatc1-mediated osteoclastogenesis to suppress osteoporosis and bone metastasis.
Zhao Y, Teng H, Deng Y, Sheldon M, Martinez C, Zhang J, Tian A, Sun Y, Nakagawa S, Yao F, Wang H, Ma L
Research square 2023 Mar 20;
Research square 2023 Mar 20;
Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation.
Zhang C, Liu Z, Wang X, Zhang B, Cui L, Hu Q, Hu B, Cao K, Shan W, Shi H, Wang R
iScience 2023 Jun 16;26(6):106852
iScience 2023 Jun 16;26(6):106852
The ratio of alpha-calcitonin gene-related peptide to substance P is associated with the transition of bone metabolic states during aging and healing.
Liu Q, Yu M, Liao M, Ran Z, Tang X, Hu J, Su B, Fu G, Wu Q
Journal of molecular histology 2023 Dec;54(6):689-702
Journal of molecular histology 2023 Dec;54(6):689-702
Single-cell multi-omics analysis of human testicular germ cell tumor reveals its molecular features and microenvironment.
Lu X, Luo Y, Nie X, Zhang B, Wang X, Li R, Liu G, Zhou Q, Liu Z, Fan L, Hotaling JM, Zhang Z, Bo H, Guo J
Nature communications 2023 Dec 20;14(1):8462
Nature communications 2023 Dec 20;14(1):8462
Babam2 negatively regulates osteoclastogenesis by interacting with Hey1 to inhibit Nfatc1 transcription.
Jin F, Zhu Y, Liu M, Wang R, Cui Y, Wu Y, Liu G, Wang Y, Wang X, Ren Z
International journal of biological sciences 2022;18(11):4482-4496
International journal of biological sciences 2022;18(11):4482-4496
The Dibenzyl Isoquinoline Alkaloid Berbamine Ameliorates Osteoporosis by Inhibiting Bone Resorption.
Zhang C, Zhong Z, Sang W, Ghorbani F, Ghalandari B, Mohamadali M, Irani S, Qian Z, Yi C, Yu B
Frontiers in endocrinology 2022;13:885507
Frontiers in endocrinology 2022;13:885507
Extracellular Vesicles Derived From Murine Cementoblasts Possess the Potential to Increase Receptor Activator of Nuclear Factor-κB Ligand-Induced Osteoclastogenesis.
Sato R, Maruyama K, Nemoto E, Sakisaka Y, Suzuki S, Li J, Numazaki K, Tada H, Yamada S
Frontiers in physiology 2022;13:825596
Frontiers in physiology 2022;13:825596
Gasdermin D maintains bone mass by rewiring the endo-lysosomal pathway of osteoclastic bone resorption.
Li M, Yang D, Yan H, Tang Z, Jiang D, Zhang J, Chi Z, Nie W, Zhen W, Yu W, Chen S, Wang Z, Yu Q, Zhang X, Yang F, Fan S, Lin X, Wang D
Developmental cell 2022 Oct 24;57(20):2365-2380.e8
Developmental cell 2022 Oct 24;57(20):2365-2380.e8
Complete abrogation of key osteoclast markers with a membrane-anchored tissue inhibitor of metalloproteinase : a novel approach in the prevention of osteoclastogenesis.
Zhang Y, Jiang B, Zhang P, Chiu SK, Lee MH
Bone & joint research 2022 Nov;11(11):763-776
Bone & joint research 2022 Nov;11(11):763-776
Effects of urolithin A on osteoclast differentiation induced by receptor activator of nuclear factor-κB ligand via bone morphogenic protein 2.
Wang Z, Qi G, Li Z, Cui X, Guo S, Zhang Y, Cai P, Wang X
Bioengineered 2022 Mar;13(3):5064-5078
Bioengineered 2022 Mar;13(3):5064-5078
Sickle cell disease promotes sex-dependent pathological bone loss through enhanced cathepsin proteolytic activity in mice.
Selma J, Song H, Rivera C, Douglas S, Akella A, Bollavaram K, Thompson N, Platt MO, Botchwey EA
Blood advances 2022 Mar 8;6(5):1381-1393
Blood advances 2022 Mar 8;6(5):1381-1393
Propionate and butyrate attenuate macrophage pyroptosis and osteoclastogenesis induced by CoCrMo alloy particles.
Wu YL, Zhang CH, Teng Y, Pan Y, Liu NC, Liu PX, Zhu X, Su XL, Lin J
Military Medical Research 2022 Aug 23;9(1):46
Military Medical Research 2022 Aug 23;9(1):46
Farnesoid X receptor agonist attenuates subchondral bone osteoclast fusion and osteochondral pathologies of osteoarthritis via suppressing JNK1/2/NFATc1 pathway.
Hu W, Cai C, Li Y, Kang F, Chu T, Dong S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22243
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2022 Apr;36(4):e22243
BCI Suppresses RANKL-Mediated Osteoclastogenesis and Alleviates Ovariectomy-Induced Bone Loss.
Cai C, Hu W, Zhang Y, Hu X, Yang S, Qiu H, Wang R, Ma M, Qiu Y, Chu T
Frontiers in pharmacology 2021;12:772540
Frontiers in pharmacology 2021;12:772540
Mechanical loading attenuates breast cancer-associated bone metastasis in obese mice by regulating the bone marrow microenvironment.
Huang M, Liu H, Zhu L, Li X, Li J, Yang S, Liu D, Song X, Yokota H, Zhang P
Journal of cellular physiology 2021 Sep;236(9):6391-6406
Journal of cellular physiology 2021 Sep;236(9):6391-6406
Andrographolide prevents bone loss via targeting estrogen-related receptor-α-regulated metabolic adaption of osteoclastogenesis.
Huang T, Fu X, Wang N, Yang M, Zhang M, Wang B, Chen T, Majaz S, Wang H, Wong CW, Liu J, Guan M
British journal of pharmacology 2021 Nov;178(21):4352-4367
British journal of pharmacology 2021 Nov;178(21):4352-4367
Interleukin-1 induces receptor activator of nuclear factor-κB ligand-independent osteoclast differentiation in RAW264.7 cells.
Liao R, Feng Z, Li W, Liu R, Xu X, Yao S, Tian J
Experimental and therapeutic medicine 2021 Jun;21(6):640
Experimental and therapeutic medicine 2021 Jun;21(6):640
BMP2 immune complexes promote new bone formation by facilitating the direct contact between osteoclasts and osteoblasts.
Xu Y, Yang Y, Hua Z, Li S, Yang Z, Liu Q, Fu G, Ji P, Wu Q
Biomaterials 2021 Aug;275:120890
Biomaterials 2021 Aug;275:120890
4-Hexylresorcinol inhibits osteoclastogenesis by suppressing the NF-κB signaling pathway and reverses bone loss in ovariectomized mice.
Yi W, Liu T, Gao X, Xie Y, Liu M
Experimental and therapeutic medicine 2021 Apr;21(4):354
Experimental and therapeutic medicine 2021 Apr;21(4):354
Pristimerin Suppresses RANKL-Induced Osteoclastogenesis and Ameliorates Ovariectomy-Induced Bone Loss.
Qi D, Liu H, Sun X, Luo D, Zhu M, Tao T, Gao C, Zhou C, Zhou W, Xiao J
Frontiers in pharmacology 2020;11:621110
Frontiers in pharmacology 2020;11:621110
Cytisine attenuates bone loss of ovariectomy mouse by preventing RANKL-induced osteoclastogenesis.
Qian Z, Zhong Z, Ni S, Li D, Zhang F, Zhou Y, Kang Z, Qian J, Yu B
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Journal of cellular and molecular medicine 2020 Sep;24(17):10112-10127
Schisandrin A restrains osteoclastogenesis by inhibiting reactive oxygen species and activating Nrf2 signalling.
Ni S, Qian Z, Yuan Y, Li D, Zhong Z, Ghorbani F, Zhang X, Zhang F, Zhang Z, Liu Z, Yu B
Cell proliferation 2020 Oct;53(10):e12882
Cell proliferation 2020 Oct;53(10):e12882
PERK controls bone homeostasis through the regulation of osteoclast differentiation and function.
Guo J, Ren R, Sun K, Yao X, Lin J, Wang G, Guo Z, Xu T, Guo F
Cell death & disease 2020 Oct 13;11(10):847
Cell death & disease 2020 Oct 13;11(10):847
Vinpocetine inhibits RANKL-induced osteoclastogenesis and attenuates ovariectomy-induced bone loss.
Zhu M, Liu H, Sun K, Liu J, Mou Y, Qi D, Zhou C, Abudunaibi M, Tasiken B, Li J, Cheng H, Huang H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109769
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109769
Circadian control of the secretory pathway maintains collagen homeostasis.
Chang J, Garva R, Pickard A, Yeung CC, Mallikarjun V, Swift J, Holmes DF, Calverley B, Lu Y, Adamson A, Raymond-Hayling H, Jensen O, Shearer T, Meng QJ, Kadler KE
Nature cell biology 2020 Jan;22(1):74-86
Nature cell biology 2020 Jan;22(1):74-86
Fluid Shear Stress Suppresses Osteoclast Differentiation in RAW264.7 Cells through Extracellular Signal-Regulated Kinase 5 (ERK5) Signaling Pathway.
Ma C, Geng B, Zhang X, Li R, Yang X, Xia Y
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 8;26:e918370
Medical science monitor : international medical journal of experimental and clinical research 2020 Jan 8;26:e918370
Cysteine cathepsins are altered by flow within an engineered in vitro microvascular niche.
Douglas SA, Haase K, Kamm RD, Platt MO
APL bioengineering 2020 Dec;4(4):046102
APL bioengineering 2020 Dec;4(4):046102
ClC-7 Regulates the Pattern and Early Development of Craniofacial Bone and Tooth.
Zhang Y, Ji D, Li L, Yang S, Zhang H, Duan X
Theranostics 2019;9(5):1387-1400
Theranostics 2019;9(5):1387-1400
Tetrandrine Prevents Bone Loss in Ovariectomized Mice by Inhibiting RANKL-Induced Osteoclastogenesis.
Zhong Z, Qian Z, Zhang X, Chen F, Ni S, Kang Z, Zhang F, Li D, Yu B
Frontiers in pharmacology 2019;10:1530
Frontiers in pharmacology 2019;10:1530
Mannan-Binding Lectin Attenuates Inflammatory Arthritis Through the Suppression of Osteoclastogenesis.
Dong L, Wu J, Chen K, Xie J, Wang Y, Li D, Liu Y, Yin A, Zhao Y, Han Y, Zhou J, Zhang L, Chen Z, Zuo D
Frontiers in immunology 2019;10:1239
Frontiers in immunology 2019;10:1239
miR-142-5p promotes the osteoclast differentiation of bone marrow-derived macrophages via PTEN/PI3K/AKT/FoxO1 pathway.
Lou Z, Peng Z, Wang B, Li X, Li X, Zhang X
Journal of bone and mineral metabolism 2019 Sep;37(5):815-824
Journal of bone and mineral metabolism 2019 Sep;37(5):815-824
Ankle loading ameliorates bone loss from breast cancer-associated bone metastasis.
Yang S, Liu H, Zhu L, Li X, Liu D, Song X, Yokota H, Zhang P
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Oct;33(10):10742-10752
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Oct;33(10):10742-10752
Treadmill Running in Established Phase Arthritis Inhibits Joint Destruction in Rat Rheumatoid Arthritis Models.
Fujii Y, Inoue H, Arai Y, Shimomura S, Nakagawa S, Kishida T, Tsuchida S, Kamada Y, Kaihara K, Shirai T, Terauchi R, Toyama S, Ikoma K, Mazda O, Mikami Y
International journal of molecular sciences 2019 Oct 15;20(20)
International journal of molecular sciences 2019 Oct 15;20(20)
Low‑frequency pulsed electromagnetic field inhibits RANKL‑induced osteoclastic differentiation in RAW264.7 cells by scavenging reactive oxygen species.
Pi Y, Liang H, Yu Q, Yin Y, Xu H, Lei Y, Han Z, Tian J
Molecular medicine reports 2019 May;19(5):4129-4136
Molecular medicine reports 2019 May;19(5):4129-4136
Silencing of Aberrant Secretory Protein Expression by Disease-Associated Mutations.
Tikhonova EB, Karamysheva ZN, von Heijne G, Karamyshev AL
Journal of molecular biology 2019 Jun 28;431(14):2567-2580
Journal of molecular biology 2019 Jun 28;431(14):2567-2580
Hesperetin suppresses RANKL-induced osteoclastogenesis and ameliorates lipopolysaccharide-induced bone loss.
Liu H, Dong Y, Gao Y, Zhao L, Cai C, Qi D, Zhu M, Zhao L, Liu C, Guo F, Xiao J, Huang H
Journal of cellular physiology 2019 Jul;234(7):11009-11022
Journal of cellular physiology 2019 Jul;234(7):11009-11022
Sequential, but not Concurrent, Incubation of Cathepsin K and L with Type I Collagen Results in Extended Proteolysis.
Parks AN, Nahata J, Edouard NE, Temenoff JS, Platt MO
Scientific reports 2019 Apr 1;9(1):5399
Scientific reports 2019 Apr 1;9(1):5399
Effects of Taxifolin on Osteoclastogenesis in vitro and in vivo.
Cai C, Liu C, Zhao L, Liu H, Li W, Guan H, Zhao L, Xiao J
Frontiers in pharmacology 2018;9:1286
Frontiers in pharmacology 2018;9:1286
Constitutive Activation of β-Catenin in Differentiated Osteoclasts Induces Bone Loss in Mice.
Sui X, Deng S, Liu M, Fan L, Wang Y, Xu H, Sun Y, Kishen A, Zhang Q
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(5):2091-2102
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;48(5):2091-2102
Simvastatin improves oral implant osseointegration via enhanced autophagy and osteogenesis of BMSCs and inhibited osteoclast activity.
Xu R, Shi G, Xu L, Gu Q, Fu Y, Zhang P, Cheng J, Jiang H
Journal of tissue engineering and regenerative medicine 2018 May;12(5):1209-1219
Journal of tissue engineering and regenerative medicine 2018 May;12(5):1209-1219
YAP1 is essential for osteoclastogenesis through a TEADs-dependent mechanism.
Zhao L, Guan H, Song C, Wang Y, Liu C, Cai C, Zhu H, Liu H, Zhao L, Xiao J
Bone 2018 May;110:177-186
Bone 2018 May;110:177-186
SNAI1, an endothelial-mesenchymal transition transcription factor, promotes the early phase of ocular neovascularization.
Sun JX, Chang TF, Li MH, Sun LJ, Yan XC, Yang ZY, Liu Y, Xu WQ, Lv Y, Su JB, Liang L, Han H, Dou GR, Wang YS
Angiogenesis 2018 Aug;21(3):635-652
Angiogenesis 2018 Aug;21(3):635-652
Pulsed electromagnetic field inhibits RANKL-dependent osteoclastic differentiation in RAW264.7 cells through the Ca(2+)-calcineurin-NFATc1 signaling pathway.
Zhang J, Xu H, Han Z, Chen P, Yu Q, Lei Y, Li Z, Zhao M, Tian J
Biochemical and biophysical research communications 2017 Jan 8;482(2):289-295
Biochemical and biophysical research communications 2017 Jan 8;482(2):289-295
Cathepsin K in Lymphangioleiomyomatosis: LAM Cell-Fibroblast Interactions Enhance Protease Activity by Extracellular Acidification.
Dongre A, Clements D, Fisher AJ, Johnson SR
The American journal of pathology 2017 Aug;187(8):1750-1762
The American journal of pathology 2017 Aug;187(8):1750-1762
Role of endoplasmic reticulum stress in disuse osteoporosis.
Li J, Yang S, Li X, Liu D, Wang Z, Guo J, Tan N, Gao Z, Zhao X, Zhang J, Gou F, Yokota H, Zhang P
Bone 2017 Apr;97:2-14
Bone 2017 Apr;97:2-14
Increased expression and activation of cathepsin K in human osteoarthritic cartilage and synovial tissues.
Kozawa E, Cheng XW, Urakawa H, Arai E, Yamada Y, Kitamura S, Sato K, Kuzuya M, Ishiguro N, Nishida Y
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2016 Jan;34(1):127-34
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2016 Jan;34(1):127-34
Expression profile of cathepsins indicates the potential of cathepsins B and D as prognostic factors in breast cancer patients.
Sun T, Jiang D, Zhang L, Su Q, Mao W, Jiang C
Oncology letters 2016 Jan;11(1):575-583
Oncology letters 2016 Jan;11(1):575-583
Stem cell-derived tissue-associated regulatory T cells ameliorate the development of autoimmunity.
Haque M, Song J, Fino K, Sandhu P, Song X, Lei F, Zheng S, Ni B, Fang D, Song J
Scientific reports 2016 Feb 5;6:20588
Scientific reports 2016 Feb 5;6:20588
Knee loading inhibits osteoclast lineage in a mouse model of osteoarthritis.
Li X, Yang J, Liu D, Li J, Niu K, Feng S, Yokota H, Zhang P
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- ROS1728 cells were subjected to SDS PAGE followed by western blot with 11239-1-AP( CTSK Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cathepsin K antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Cathepsin K. This antibody recognizes human, mouse, rat antigen. The Cathepsin K antibody has been validated for the following applications: ELISA, IHC, WB analysis.
