Antibody data
- Antibody Data
- Antigen structure
- References [20]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 60312-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- CDK2 antibody
- Antibody type
- Monoclonal
- Description
- CDK2 antibody (Cat. #60312-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgM
- Antibody clone number
- 4E2E10
- Vial size
- 20ul, 150ul
Submitted references Rab25 is involved in hypospadias via the β1 integrin/EGFR pathway.
A Circular RNA Generated from Nebulin (NEB) Gene Splicing Promotes Skeletal Muscle Myogenesis in Cattle as Detected by a Multi-Omics Approach.
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Ebastine exerts antitumor activity and induces autophagy by activating AMPK/ULK1 signaling in an IPMK-dependent manner in osteosarcoma.
Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma.
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening.
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
CYP2C8 Suppress Proliferation, Migration, Invasion and Sorafenib Resistance of Hepatocellular Carcinoma via PI3K/Akt/p27(kip1) Axis.
Discovery and Verification of Key Liver Cancer Genes and Alternative Splicing Events Based on Second-Generation Sequencing Data Analysis.
MICAL2 Contributes to Gastric Cancer Cell Proliferation by Promoting YAP Dephosphorylation and Nuclear Translocation.
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04.
Poly(rC) binding protein 2 (PCBP2) promotes the viability of human gastric cancer cells by regulating CDK2.
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma.
Zhang Z, Zhang Q, Liu Z, Wang C, Chen H, Luo X, Shen L, Long C, Wei G, Liu X
Experimental cell research 2024 Mar 15;436(2):113980
Experimental cell research 2024 Mar 15;436(2):113980
A Circular RNA Generated from Nebulin (NEB) Gene Splicing Promotes Skeletal Muscle Myogenesis in Cattle as Detected by a Multi-Omics Approach.
Huang K, Li Z, Zhong D, Yang Y, Yan X, Feng T, Wang X, Zhang L, Shen X, Chen M, Luo X, Cui K, Huang J, Rehman SU, Jiang Y, Shi D, Pauciullo A, Tang X, Liu Q, Li H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(3):e2300702
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jan;11(3):e2300702
Identification and Validation of a Prognostic Signature Derived from the Cancer Stem Cells for Oral Squamous Cell Carcinoma.
Shi M, Huang K, Wei J, Wang S, Yang W, Wang H, Li Y
International journal of molecular sciences 2024 Jan 14;25(2)
International journal of molecular sciences 2024 Jan 14;25(2)
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway.
Wang P, Zhang H, Guo K, Liu C, Chen S, Pu B, Chen S, Feng T, Jiao H, Gao C
Oncology letters 2024 Apr;27(4):140
Oncology letters 2024 Apr;27(4):140
Ebastine exerts antitumor activity and induces autophagy by activating AMPK/ULK1 signaling in an IPMK-dependent manner in osteosarcoma.
Pan Z, Li SJ, Guo H, Li ZH, Fei X, Chang SM, Yang QC, Cheng DD
International journal of biological sciences 2023;19(2):537-551
International journal of biological sciences 2023;19(2):537-551
Adipocyte-Derived Exosomal NOX4-Mediated Oxidative Damage Induces Premature Placental Senescence in Obese Pregnancy.
Tao Y, Chen W, Xu H, Xu J, Yang H, Luo X, Chen M, He J, Bai Y, Qi H
International journal of nanomedicine 2023;18:4705-4726
International journal of nanomedicine 2023;18:4705-4726
IGFBP3 induced by the TGF-β/EGFRvIII transactivation contributes to the malignant phenotype of glioblastoma.
Zhang X, Wang G, Gong Y, Zhao L, Song P, Zhang H, Zhang Y, Ju H, Wang X, Wang B, Ren H, Zhu X, Dong Y
iScience 2023 May 19;26(5):106639
iScience 2023 May 19;26(5):106639
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway.
Yin W, Fu X, Chang W, Han L, Meng J, Cao A, Ren X, Fan Z, Zhou S
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
The Journal of pharmacy and pharmacology 2023 Jan 31;75(1):87-97
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Peng T, Liu M, Hu L, Guo D, Wang D, Qi B, Ren G, Hu C, Zhang F, Chun HJ, Song L, Hu J, Li Y
Biology direct 2022 Nov 16;17(1):32
Biology direct 2022 Nov 16;17(1):32
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
Wu J, Yang C, Yang M, Liang Z, Wu Y, Kong X, Fan H, Wang S, Ning C, Xiao W, Jin Y, Yi J, Yuan Z
Ecotoxicology and environmental safety 2022 Jun 1;237:113531
Ecotoxicology and environmental safety 2022 Jun 1;237:113531
Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening.
Wang L, Li C, Chen P, Liu C, Cui Z, Deng S, Yang H
ACS pharmacology & translational science 2022 Jul 8;5(7):479-490
ACS pharmacology & translational science 2022 Jul 8;5(7):479-490
Hsa_circ_0005050 interacts with ILF3 and affects cell apoptosis and proliferation by disrupting the balance between p53 and p65.
Tan J, Sun M, Yin J, Zhou Q, Zhao R, Chen Q, Sun H, Jiang C, Li S, He Y
Chemico-biological interactions 2022 Dec 1;368:110208
Chemico-biological interactions 2022 Dec 1;368:110208
CYP2C8 Suppress Proliferation, Migration, Invasion and Sorafenib Resistance of Hepatocellular Carcinoma via PI3K/Akt/p27(kip1) Axis.
Zhou X, Li TM, Luo JZ, Lan CL, Wei ZL, Fu TH, Liao XW, Zhu GZ, Ye XP, Peng T
Journal of hepatocellular carcinoma 2021;8:1323-1338
Journal of hepatocellular carcinoma 2021;8:1323-1338
Discovery and Verification of Key Liver Cancer Genes and Alternative Splicing Events Based on Second-Generation Sequencing Data Analysis.
Cui M, Bai M, Zheng L, Bao Y, Sun L, Yu C, Sun Y, Song Z, Wang G, Yu Z, Li Y, Huang Y
Biological & pharmaceutical bulletin 2021;44(10):1433-1444
Biological & pharmaceutical bulletin 2021;44(10):1433-1444
MICAL2 Contributes to Gastric Cancer Cell Proliferation by Promoting YAP Dephosphorylation and Nuclear Translocation.
Qi C, Min P, Wang Q, Wang Y, Song Y, Zhang Y, Bibi M, Du J
Oxidative medicine and cellular longevity 2021;2021:9955717
Oxidative medicine and cellular longevity 2021;2021:9955717
Bovine Milk Exosomes Affect Proliferation and Protect Macrophages against Cisplatin-Induced Cytotoxicity.
Matic S, D'Souza DH, Wu T, Pangloli P, Dia VP
Immunological investigations 2020 Oct;49(7):711-725
Immunological investigations 2020 Oct;49(7):711-725
LncRNA FEZF1-AS1 Promotes TGF-β2-Mediated Proliferation and Migration in Human Lens Epithelial Cells SRA01/04.
Wang Y, Chen L, Gu Y, Wang Y, Yuan Y, Zhu Q, Bi M, Gu S
Journal of ophthalmology 2019;2019:4736203
Journal of ophthalmology 2019;2019:4736203
Poly(rC) binding protein 2 (PCBP2) promotes the viability of human gastric cancer cells by regulating CDK2.
Chen C, Lei J, Zheng Q, Tan S, Ding K, Yu C
FEBS open bio 2018 May;8(5):764-773
FEBS open bio 2018 May;8(5):764-773
The role of the ATM/Chk/P53 pathway in mediating DNA damage in hand-foot syndrome induced by PLD.
Yang J, Qiao L, Zeng Z, Wang J, Zhu T, Wei J, Wu M, Ye S, Huang X, Ma D, Liu R, Gao Q
Toxicology letters 2017 Jan 4;265:131-139
Toxicology letters 2017 Jan 4;265:131-139
High expression of N-myc (and STAT) interactor predicts poor prognosis and promotes tumor growth in human glioblastoma.
Meng D, Chen Y, Yun D, Zhao Y, Wang J, Xu T, Li X, Wang Y, Yuan L, Sun R, Song X, Huai C, Hu L, Yang S, Min T, Chen J, Chen H, Lu D
Oncotarget 2015 Mar 10;6(7):4901-19
Oncotarget 2015 Mar 10;6(7):4901-19
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 60312-1-Ig( CDK2 Antibody) at dilution of 1:1000
- Other comments
- WB
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human cervical cancer tissue slide using 60312-1-Ig( CDK2 Antibody) at dilution of 1:50 (under 40x lens)
- Other comments
- IHC