Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 20170-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20170-1-AP, RRID:AB_10665373
- Product name
- KGA-Specific antibody
- Antibody type
- Polyclonal
- Description
- KGA-Specific antibody (Cat. #20170-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor.
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival.
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor.
Inhibition of glutaminase 1-mediated glutaminolysis improves pathological cardiac remodeling.
Depletion of Intracellular Glutamine Pools Triggers Toxoplasma gondii Stage Conversion in Human Glutamatergic Neurons.
CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion.
Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase.
A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues.
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent.
Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer.
Evidence for Altered Glutamine Metabolism in Human Immunodeficiency Virus Type 1 Infected Primary Human CD4(+) T Cells.
T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.
CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.
Jablonowski CM, Quarni W, Singh S, Tan H, Bostanthirige DH, Jin H, Fang J, Chang TC, Finkelstein D, Cho JH, Hu D, Pagala V, Sakurada SM, Pruett-Miller SM, Wang R, Murphy A, Freeman K, Peng J, Davidoff AM, Wu G, Yang J
eLife 2024 Mar 15;12
eLife 2024 Mar 15;12
Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival.
Goswami MT, Weh E, Subramanya S, Weh KM, Durumutla HB, Hager H, Miller N, Chaudhury S, Andren A, Sajjakulnukit P, Zhang L, Besirli CG, Lyssiotis CA, Wubben TJ
bioRxiv : the preprint server for biology 2024 Jul 1;
bioRxiv : the preprint server for biology 2024 Jul 1;
Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing is associated with therapeutic response to splicing inhibitor.
Jablonowski C, Quarni W, Singh S, Tan H, Bostanthirige DH, Jin H, Fang J, Chang TC, Finkelstein D, Cho JH, Hu D, Pagala V, Sakurada SM, Pruett-Miller SM, Wang R, Murphy A, Freeman K, Peng J, Davidoff AM, Wu G, Yang J
bioRxiv : the preprint server for biology 2023 Nov 20;
bioRxiv : the preprint server for biology 2023 Nov 20;
Inhibition of glutaminase 1-mediated glutaminolysis improves pathological cardiac remodeling.
Yoshikawa S, Nagao M, Toh R, Shinohara M, Iino T, Irino Y, Nishimori M, Tanaka H, Satomi-Kobayashi S, Ishida T, Hirata KI
American journal of physiology. Heart and circulatory physiology 2022 May 1;322(5):H749-H761
American journal of physiology. Heart and circulatory physiology 2022 May 1;322(5):H749-H761
Depletion of Intracellular Glutamine Pools Triggers Toxoplasma gondii Stage Conversion in Human Glutamatergic Neurons.
Bando H, Fukuda Y, Watanabe N, Olawale JT, Kato K
Frontiers in cellular and infection microbiology 2021;11:788303
Frontiers in cellular and infection microbiology 2021;11:788303
CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion.
Russo GL, Sonsalla G, Natarajan P, Breunig CT, Bulli G, Merl-Pham J, Schmitt S, Giehrl-Schwab J, Giesert F, Jastroch M, Zischka H, Wurst W, Stricker SH, Hauck SM, Masserdotti G, Götz M
Cell stem cell 2021 Mar 4;28(3):524-534.e7
Cell stem cell 2021 Mar 4;28(3):524-534.e7
Mitochondrial Metabolism behind Region-Specific Resistance to Ischemia-Reperfusion Injury in Gerbil Hippocampus. Role of PKCβII and Phosphate-Activated Glutaminase.
Beręsewicz-Haller M, Krupska O, Bochomulski P, Dudzik D, Chęcińska A, Hilgier W, Barbas C, Zablocki K, Zablocka B
International journal of molecular sciences 2021 Aug 7;22(16)
International journal of molecular sciences 2021 Aug 7;22(16)
A facile and sensitive method of quantifying glutaminase binding to its inhibitor CB-839 in tissues.
Chen Y, Zhao Y, Bajor DL, Wang Z, Selfridge JE
Journal of genetics and genomics = Yi chuan xue bao 2020 Jul 20;47(7):389-395
Journal of genetics and genomics = Yi chuan xue bao 2020 Jul 20;47(7):389-395
Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway.
Li B, Cao Y, Meng G, Qian L, Xu T, Yan C, Luo O, Wang S, Wei J, Ding Y, Yu D
EBioMedicine 2019 Jan;39:239-254
EBioMedicine 2019 Jan;39:239-254
The Progestin Receptor Interactome in the Female Mouse Hypothalamus: Interactions with Synaptic Proteins Are Isoform Specific and Ligand Dependent.
Acharya KD, Nettles SA, Sellers KJ, Im DD, Harling M, Pattanayak C, Vardar-Ulu D, Lichti CF, Huang S, Edwards DP, Srivastava DP, Denner L, Tetel MJ
eNeuro 2017 Sep-Oct;4(5)
eNeuro 2017 Sep-Oct;4(5)
Metabolic Differences in Glutamine Utilization Lead to Metabolic Vulnerabilities in Prostate Cancer.
Zacharias NM, McCullough C, Shanmugavelandy S, Lee J, Lee Y, Dutta P, McHenry J, Nguyen L, Norton W, Jones LW, Bhattacharya PK
Scientific reports 2017 Nov 23;7(1):16159
Scientific reports 2017 Nov 23;7(1):16159
Evidence for Altered Glutamine Metabolism in Human Immunodeficiency Virus Type 1 Infected Primary Human CD4(+) T Cells.
Hegedus A, Kavanagh Williamson M, Khan MB, Dias Zeidler J, Da Poian AT, El-Bacha T, Struys EA, Huthoff H
AIDS research and human retroviruses 2017 Dec;33(12):1236-1247
AIDS research and human retroviruses 2017 Dec;33(12):1236-1247
T Helper Cell Activation and Expansion Is Sensitive to Glutaminase Inhibition under Both Hypoxic and Normoxic Conditions.
Sener Z, Cederkvist FH, Volchenkov R, Holen HL, Skålhegg BS
PloS one 2016;11(7):e0160291
PloS one 2016;11(7):e0160291
CFIm25 regulates glutaminase alternative terminal exon definition to modulate miR-23 function.
Masamha CP, Xia Z, Peart N, Collum S, Li W, Wagner EJ, Shyu AB
RNA (New York, N.Y.) 2016 Jun;22(6):830-8
RNA (New York, N.Y.) 2016 Jun;22(6):830-8
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
Jacque N, Ronchetti AM, Larrue C, Meunier G, Birsen R, Willems L, Saland E, Decroocq J, Maciel TT, Lambert M, Poulain L, Hospital MA, Sujobert P, Joseph L, Chapuis N, Lacombe C, Moura IC, Demo S, Sarry JE, Recher C, Mayeux P, Tamburini J, Bouscary D
Blood 2015 Sep 10;126(11):1346-56
Blood 2015 Sep 10;126(11):1346-56
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia.
Herranz D, Ambesi-Impiombato A, Sudderth J, Sánchez-Martín M, Belver L, Tosello V, Xu L, Wendorff AA, Castillo M, Haydu JE, Márquez J, Matés JM, Kung AL, Rayport S, Cordon-Cardo C, DeBerardinis RJ, Ferrando AA
Nature medicine 2015 Oct;21(10):1182-9
Nature medicine 2015 Oct;21(10):1182-9
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 20170-1-AP(GLS antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 20170-1-AP(GLS antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The KGA-Specific antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human KGA-Specific. This antibody recognizes human,mouse,rat antigen. The KGA-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.
