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- References [14]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12339-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12339-1-AP, RRID:AB_2183305
- Product name
- SDPR antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SDPR antibody (Cat. #12339-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Cavin-1/Caveolin-1 interaction attenuates BMP/Smad signaling in pulmonary hypertension by interfering with BMPR2/Caveolin-1 binding.
Cavin-2 promotes fibroblast-to-myofibroblast trans-differentiation and aggravates cardiac fibrosis.
Cavin-2 loss exacerbates hypoxia-induced pulmonary hypertension with excessive eNOS phosphorylation and protein nitration.
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1.
Requirement of Cavin-2 for the expression and stability of IRĪ² in adequate adipocyte differentiation.
Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq.
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Prognostic values, ceRNA network, and immune regulation function of SDPR in KRAS-mutant lung cancer.
Dynamin 2 is required for GPVI signaling and platelet hemostatic function in mice.
EphB1 interaction with caveolin-1 in endothelial cells modulates caveolae biogenesis.
Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis.
Cavin-2 is a specific marker for detection of well-differentiated liposarcoma.
P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain.
Down-regulation of the cavin family proteins in breast cancer.
Tomita S, Nakanishi N, Ogata T, Higuchi Y, Sakamoto A, Tsuji Y, Suga T, Matoba S
Communications biology 2024 Jan 5;7(1):40
Communications biology 2024 Jan 5;7(1):40
Cavin-2 promotes fibroblast-to-myofibroblast trans-differentiation and aggravates cardiac fibrosis.
Higuchi Y, Ogata T, Nakanishi N, Nishi M, Tsuji Y, Tomita S, Conway SJ, Matoba S
ESC heart failure 2024 Feb;11(1):167-178
ESC heart failure 2024 Feb;11(1):167-178
Cavin-2 loss exacerbates hypoxia-induced pulmonary hypertension with excessive eNOS phosphorylation and protein nitration.
Kasahara T, Ogata T, Nakanishi N, Tomita S, Higuchi Y, Maruyama N, Hamaoka T, Matoba S
Heliyon 2023 Jun;9(6):e17193
Heliyon 2023 Jun;9(6):e17193
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1.
Cen X, Chen Q, Wang B, Xu H, Wang X, Ling Y, Zhang X, Qin D
Cell communication and signaling : CCS 2022 Nov 28;20(1):191
Cell communication and signaling : CCS 2022 Nov 28;20(1):191
Requirement of Cavin-2 for the expression and stability of IRĪ² in adequate adipocyte differentiation.
Higuchi Y, Ogata T, Nakanishi N, Nishi M, Sakamoto A, Tsuji Y, Tomita S, Matoba S
Molecular metabolism 2022 Jan;55:101416
Molecular metabolism 2022 Jan;55:101416
Cellular heterogeneity of human fallopian tubes in normal and hydrosalpinx disease states identified using scRNA-seq.
Ulrich ND, Shen YC, Ma Q, Yang K, Hannum DF, Jones A, Machlin J, Randolph JF Jr, Smith YR, Schon SB, Shikanov A, Marsh EE, Lieberman R, Gurczynski SJ, Moore BB, Li JZ, Hammoud S
Developmental cell 2022 Apr 11;57(7):914-929.e7
Developmental cell 2022 Apr 11;57(7):914-929.e7
Engineering Extracellular Vesicles Restore the Impaired Cellular Uptake and Attenuate Intervertebral Disc Degeneration.
Liao Z, Liu H, Ma L, Lei J, Tong B, Li G, Ke W, Wang K, Feng X, Hua W, Li S, Yang C
ACS nano 2021 Sep 28;15(9):14709-14724
ACS nano 2021 Sep 28;15(9):14709-14724
Prognostic values, ceRNA network, and immune regulation function of SDPR in KRAS-mutant lung cancer.
Luo X, Peng S, Ding S, Zeng Q, Wang R, Ma Y, Chen S, Wang Y, Wang W
Cancer cell international 2021 Jan 12;21(1):49
Cancer cell international 2021 Jan 12;21(1):49
Dynamin 2 is required for GPVI signaling and platelet hemostatic function in mice.
Eaton N, Drew C, Wieser J, Munday AD, Falet H
Haematologica 2020 May;105(5):1414-1423
Haematologica 2020 May;105(5):1414-1423
EphB1 interaction with caveolin-1 in endothelial cells modulates caveolae biogenesis.
Tiruppathi C, Regmi SC, Wang DM, Mo GCH, Toth PT, Vogel SM, Stan RV, Henkemeyer M, Minshall RD, Rehman J, Malik AB
Molecular biology of the cell 2020 May 15;31(11):1167-1182
Molecular biology of the cell 2020 May 15;31(11):1167-1182
Cavin-2 regulates the activity and stability of endothelial nitric-oxide synthase (eNOS) in angiogenesis.
Boopathy GTK, Kulkarni M, Ho SY, Boey A, Chua EWM, Barathi VA, Carney TJ, Wang X, Hong W
The Journal of biological chemistry 2017 Oct 27;292(43):17760-17776
The Journal of biological chemistry 2017 Oct 27;292(43):17760-17776
Cavin-2 is a specific marker for detection of well-differentiated liposarcoma.
Codenotti S, Vezzoli M, Poliani PL, Cominelli M, Monti E, Fanzani A
Biochemical and biophysical research communications 2017 Nov 4;493(1):660-665
Biochemical and biophysical research communications 2017 Nov 4;493(1):660-665
P-glycoprotein traffics from the nucleus to the plasma membrane in rat brain endothelium during inflammatory pain.
Tome ME, Herndon JM, Schaefer CP, Jacobs LM, Zhang Y, Jarvis CK, Davis TP
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2016 Nov;36(11):1913-1928
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2016 Nov;36(11):1913-1928
Down-regulation of the cavin family proteins in breast cancer.
Bai L, Deng X, Li Q, Wang M, An W, Deli A, Gao Z, Xie Y, Dai Y, Cong YS
Journal of cellular biochemistry 2012 Jan;113(1):322-8
Journal of cellular biochemistry 2012 Jan;113(1):322-8
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A549 cells were subjected to SDS PAGE followed by western blot with 12339-1-AP(SDPR antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SDPR antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SDPR. This antibody recognizes human,mouse,rat antigen. The SDPR antibody has been validated for the following applications: ELISA, WB, IHC analysis.
