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- Antibody Data
- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 15713-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15713-1-AP, RRID:AB_2164696
- Product name
- PIP5K1A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PIP5K1A antibody (Cat. #15713-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicity.
Effects of Gestational Diabetes Mellitus and Selenium Deficiency on the Offspring Growth and Blood Glucose Mechanisms of C57BL/6J Mice.
PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer.
β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages.
Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.
Bacterial protein MakA causes suppression of tumour cell proliferation via inhibition of PIP5K1α/Akt signalling.
The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor.
Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome-lysosome fusion.
Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells.
Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.
Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation.
Horvath JD, Casas M, Kutchukian C, Sánchez SC, Pergande MR, Cologna SM, Simó S, Dixon RE, Dickson EJ
Cell reports 2023 Oct 31;42(10):113244
Cell reports 2023 Oct 31;42(10):113244
Effects of Gestational Diabetes Mellitus and Selenium Deficiency on the Offspring Growth and Blood Glucose Mechanisms of C57BL/6J Mice.
Xu W, Gong J, Chen Y, Chen Y, Chen S, Wu Y, He Y, Li C, Yu H, Xie L
Nutrients 2023 Oct 25;15(21)
Nutrients 2023 Oct 25;15(21)
PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer.
Wang T, Sarwar M, Whitchurch JB, Collins HM, Green T, Semenas J, Ali A, Roberts CJ, Morris RD, Hubert M, Chen S, El-Schich Z, Wingren AG, Grundström T, Lundmark R, Mongan NP, Gunhaga L, Heery DM, Persson JL
Frontiers in cell and developmental biology 2022;10:798590
Frontiers in cell and developmental biology 2022;10:798590
β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages.
Li D, Zhang Q, Li L, Chen K, Yang J, Dixit D, Gimple RC, Ci S, Lu C, Hu L, Gao J, Shan D, Li Y, Zhang J, Shi Z, Gu D, Yuan W, Wu Q, Yang K, Zhao L, Qiu Z, Lv D, Gao W, Yang H, Lin F, Wang Q, Man J, Li C, Tao W, Agnihotri S, Qian X, Shi Y, You Y, Zhang N, Rich JN, Wang X
Cancer research 2022 Sep 16;82(18):3321-3334
Cancer research 2022 Sep 16;82(18):3321-3334
Proteomic analysis reveals zinc-finger CCHC-type containing protein 3 as a factor inhibiting virus infection by promoting innate signaling.
Chen X, Li Z, Wang S, Tong G, Chen K, Zhao Y
Virus research 2022 Oct 2;319:198876
Virus research 2022 Oct 2;319:198876
Bacterial protein MakA causes suppression of tumour cell proliferation via inhibition of PIP5K1α/Akt signalling.
Toh E, Baryalai P, Nadeem A, Aung KM, Chen S, Persson K, Persson JL, Uhlin BE, Wai SN
Cell death & disease 2022 Dec 6;13(12):1024
Cell death & disease 2022 Dec 6;13(12):1024
The role of PIP5K1α/pAKT and targeted inhibition of growth of subtypes of breast cancer using PIP5K1α inhibitor.
Sarwar M, Syed Khaja AS, Aleskandarany M, Karlsson R, Althobiti M, Ødum N, Mongan NP, Dizeyi N, Johnson H, Green AR, Ellis IO, Rakha EA, Persson JL
Oncogene 2019 Jan;38(3):375-389
Oncogene 2019 Jan;38(3):375-389
Phosphatidylinositol 4,5-bisphosphate controls Rab7 and PLEKHM1 membrane cycling during autophagosome-lysosome fusion.
Baba T, Toth DJ, Sengupta N, Kim YJ, Balla T
The EMBO journal 2019 Apr 15;38(8):e100312
The EMBO journal 2019 Apr 15;38(8):e100312
Targeted suppression of AR-V7 using PIP5K1α inhibitor overcomes enzalutamide resistance in prostate cancer cells.
Sarwar M, Semenas J, Miftakhova R, Simoulis A, Robinson B, Gjörloff Wingren A, Mongan NP, Heery DM, Johnsson H, Abrahamsson PA, Dizeyi N, Luo J, Persson JL
Oncotarget 2016 Sep 27;7(39):63065-63081
Oncotarget 2016 Sep 27;7(39):63065-63081
Spastic paraplegia proteins spastizin and spatacsin mediate autophagic lysosome reformation.
Chang J, Lee S, Blackstone C
The Journal of clinical investigation 2014 Dec;124(12):5249-62
The Journal of clinical investigation 2014 Dec;124(12):5249-62
Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation.
Rong Y, Liu M, Ma L, Du W, Zhang H, Tian Y, Cao Z, Li Y, Ren H, Zhang C, Li L, Chen S, Xi J, Yu L
Nature cell biology 2012 Sep;14(9):924-34
Nature cell biology 2012 Sep;14(9):924-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 15713-1-AP(PIP5K1A antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using PIP5K1A antibody 15713-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-PIP5K1A(15713-1-AP for IP and Detection).
- Sample type
- cell line
