Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 60315-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- c-SRC antibody
- Antibody type
- Monoclonal
- Description
- c-SRC antibody (Cat. #60315-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, hamster, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Hamster
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 5E10C4
- Vial size
- 20ul, 150ul
Submitted references StemRegenin 1 attenuates the RANKL-induced osteoclastogenesis via inhibiting AhR-c-src-NF-κB/p-ERK MAPK-NFATc1 signaling pathway.
Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells.
Identification and validation of the surface proteins FIBG, PDGF-β, and TGF-β on serum extracellular vesicles for non-invasive detection of colorectal cancer: experimental study.
Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway.
Src family kinases engage differential pathways for encapsulation into extracellular vesicles.
Adherens Junction Integrity Is a Critical Determinant of Sodium Iodide Symporter Residency at the Plasma Membrane of Thyroid Cells.
Mesopore Controls the Responses of Blood Clot-Immune Complex via Modulating Fibrin Network.
Matrine Impairs Platelet Function and Thrombosis and Inhibits ROS Production.
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy.
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
KIF26B, a novel oncogene, promotes proliferation and metastasis by activating the VEGF pathway in gastric cancer.
Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.
Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR.
Zhou S, Li J, Ying T, Wang Y, Wang Q, Li X, Zhao F
iScience 2024 May 17;27(5):109682
iScience 2024 May 17;27(5):109682
Osimertinib Covalently Binds to CD34 and Eliminates Myeloid Leukemia Stem/Progenitor Cells.
Xia L, Liu JY, Yang MY, Zhang XH, Jiang Y, Yin QQ, Luo CH, Liu HC, Kang ZJ, Zhang CT, Gao BB, Zhou AW, Cai HY, Waller EK, Yan JS, Lu Y
Cancer research 2024 Feb 1;84(3):479-492
Cancer research 2024 Feb 1;84(3):479-492
Identification and validation of the surface proteins FIBG, PDGF-β, and TGF-β on serum extracellular vesicles for non-invasive detection of colorectal cancer: experimental study.
Huang Z, Deng C, Ma C, He G, Tao J, Zhang L, Hu X, Mo Y, Qiu L, Zhang N, Luo C, Xing S, Xie J, Yin H
International journal of surgery (London, England) 2024 Aug 1;110(8):4672-4687
International journal of surgery (London, England) 2024 Aug 1;110(8):4672-4687
Peptide encoded by lncRNA BVES-AS1 promotes cell viability, migration, and invasion in colorectal cancer cells via the SRC/mTOR signaling pathway.
Zheng W, Guo Y, Zhang G, Bai J, Song Y, Song X, Zhu Q, Bao X, Wu G, Zhang C
PloS one 2023;18(6):e0287133
PloS one 2023;18(6):e0287133
Src family kinases engage differential pathways for encapsulation into extracellular vesicles.
Ye C, Gosser C, Runyon ED, Zha J, Cai J, Beharry Z, Rickman CB, Klingeborn M, Liu Y, Xie J, Cai H
Journal of extracellular biology 2023 Jun;2(6)
Journal of extracellular biology 2023 Jun;2(6)
Adherens Junction Integrity Is a Critical Determinant of Sodium Iodide Symporter Residency at the Plasma Membrane of Thyroid Cells.
Faria M, Vareda J, Miranda M, Bugalho MJ, Silva AL, Matos P
Cancers 2022 Oct 31;14(21)
Cancers 2022 Oct 31;14(21)
Mesopore Controls the Responses of Blood Clot-Immune Complex via Modulating Fibrin Network.
Wu S, Shan Z, Xie L, Su M, Zeng P, Huang P, Zeng L, Sheng X, Li Z, Zeng G, Chen Z, Chen Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2103608
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Jan;9(3):e2103608
Matrine Impairs Platelet Function and Thrombosis and Inhibits ROS Production.
Zhang S, Gui X, Ding Y, Tong H, Ju W, Li Y, Li Z, Zeng L, Xu K, Qiao J
Frontiers in pharmacology 2021;12:717725
Frontiers in pharmacology 2021;12:717725
Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.
Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, Xiao X, Ren X, Zhang M, Jia Q
BMC cancer 2020 Jan 13;20(1):31
BMC cancer 2020 Jan 13;20(1):31
Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy.
Wu JH, Li YN, Chen AQ, Hong CD, Zhang CL, Wang HL, Zhou YF, Li PC, Wang Y, Mao L, Xia YP, He QW, Jin HJ, Yue ZY, Hu B
EMBO molecular medicine 2020 Feb 7;12(2):e10154
EMBO molecular medicine 2020 Feb 7;12(2):e10154
Basolateral CD147 induces hepatocyte polarity loss by E-cadherin ubiquitination and degradation in hepatocellular carcinoma progress.
Lu M, Wu J, Hao ZW, Shang YK, Xu J, Nan G, Li X, Chen ZN, Bian H
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
Hepatology (Baltimore, Md.) 2018 Jul;68(1):317-332
KIF26B, a novel oncogene, promotes proliferation and metastasis by activating the VEGF pathway in gastric cancer.
Zhang H, Ma RR, Wang XJ, Su ZX, Chen X, Shi DB, Guo XY, Liu HT, Gao P
Oncogene 2017 Oct 5;36(40):5609-5619
Oncogene 2017 Oct 5;36(40):5609-5619
Endothelial cell SHP-2 negatively regulates neutrophil adhesion and promotes transmigration by enhancing ICAM-1-VE-cadherin interaction.
Yan M, Zhang X, Chen A, Gu W, Liu J, Ren X, Zhang J, Wu X, Place AT, Minshall RD, Liu G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Nov;31(11):4759-4769
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Nov;31(11):4759-4769
Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR.
Yang F, Yu X, Liu C, Qu CX, Gong Z, Liu HD, Li FH, Wang HM, He DF, Yi F, Song C, Tian CL, Xiao KH, Wang JY, Sun JP
Nature communications 2015 Sep 8;6:8202
Nature communications 2015 Sep 8;6:8202
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- CHO cells were subjected to SDS PAGE followed by western blot with 60315-1-Ig( c-SRC Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The c-SRC antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human c-SRC. This antibody recognizes human, hamster antigen. The c-SRC antibody has been validated for the following applications: ELISA, WB, IHC analysis.