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- Antibody Data
- Antigen structure
- References [105]
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- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 11097-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11097-1-AP, RRID:AB_2286705
- Product name
- SRC antibody
- Antibody type
- Polyclonal
- Description
- SRC antibody (Cat. #11097-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, hamster and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat, Hamster
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exploration of the therapeutic potential of magnoflorine against osteoarthritis progression using network pharmacology and in vitro validation.
Network pharmacology prediction and experimental validation to explore the potential mechanism of Danggui Shaoyao San against Acute Kidney Injury.
Anti-NSCLC efficacy of a novel ROR1/PI3Kα/BRD4 multi-target inhibitor.
P2Y2 receptor as a favorable predictor of gastric cancer.
EMP2 promotes hepatocellular carcinoma proliferation and invasion by activating cellular autophagy.
Galangin reduces MPTP-induced dopamine neuron injury via the autophagy dependent-PI3K/AKT pathway.
KLK8/HGF/Met signaling pathway mediates diabetes-associated hippocampal neuroinflammation in male mice.
Ellagic Acid-Loaded sEVs Encapsulated in GelMA Hydrogel Accelerate Diabetic Wound Healing by Activating EGFR on Skin Repair Cells.
HOMER3 orchestrates SRC-YAP1 activity that promotes tumor cell growth and antagonizes anti-tumor immunotherapy in prostate cancer.
The E3 ubiquitin ligase TRIM56 promotes aggregation and activation of Src protein through Lys63-linked polyubiquitination in hepatocellular carcinoma.
Effective-compounds of Jinshui Huanxian Formula acts as an SRC inhibitor to inhibit HK2-mediated H3K18 lactation and improve pulmonary fibrosis.
Spike proteins of coronaviruses activate mast cells for degranulation via stimulating Src/PI3K/AKT/Ca(2+) intracellular signaling cascade.
Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
Integrin β3 N125 glycosylation is essential for human cytomegalovirus entry into fibroblasts.
Tripterygium wilfordii polyglycoside tablets attenuated the progression of hepatocellular carcinoma by targeting IL-6 and downstream signaling pathways in a multi-target manner.
Network pharmacology and in vitro analyses reveal EGCG inhibits breast cancer progression via suppression of the EGFR/Src pathway.
A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats.
Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy.
MTHFD2 promotes osteoclastogenesis and bone loss in rheumatoid arthritis by enhancing CKMT1-mediated oxidative phosphorylation.
RhoB regulates prostate cancer cell proliferation and docetaxel sensitivity via the PI3K-AKT signaling pathway.
Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat.
Tenvermectin B, a novel macrocyclic lactone antibiotic, suppresses glioblastoma progression by targeting RhoJ.
Cancer-associated fibroblast-derived fibulin-5 promotes radioresistance in non-small-cell lung cancer.
ICAM-1-mediated Src signaling pathway plays a pivotal role in encephalomyocarditis virus entry.
Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade the host cell via clathrin-mediated endocytosis.
Combining RNA-seq, molecular docking and experimental verification to explore the mechanism of BAM15 as a potential drug for atherosclerosis.
Dual-Multivalent Aptamer-Based Drug Delivery Platform for Targeted SRC Silencing to Enhance Doxorubicin Sensitivity in Endometrial Cancer.
Modified Gegen Qinlian Decoction modulated the gut microbiome and bile acid metabolism and restored the function of goblet cells in a mouse model of ulcerative colitis.
Pan-cancer analysis predict that FAT1 is a therapeutic target and immunotherapy biomarker for multiple cancer types including non-small cell lung cancer.
Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway.
NAMPT enhances LOX expression and promotes metastasis in human chondrosarcoma cells by inhibiting miR-26b-5p synthesis.
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.
Modulation of SRC by SNTB1 activates the Hippo-YAP pathway during colon adenocarcinoma metastasis.
Quercetin improves the protection of hydroxysafflor yellow a against cerebral ischemic injury by modulating of blood-brain barrier and src-p-gp-mmp-9 signalling.
RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia.
Erythroid-intrinsic activation of TLR8 impairs erythropoiesis in inherited anemia.
Curcumin suppresses metastasis, invasion, and proliferation in osteosarcoma cells by regulating the EGFR/Src signaling axis.
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Adaptor protein CEMIP reduces the chemosensitivity of small cell lung cancer via activation of an SRC-YAP oncogenic module.
Cyberpharmacology uncover the mechanism of the total Rhizoma Coptidis extracts ameliorate chronic atrophic gastritis.
Fraxin represses NF-κB pathway via inhibiting the activation of epidermal growth factor receptor to ameliorate diabetic renal tubulointerstitial fibrosis.
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer.
Dahuang Zhechong pill attenuates hepatic sinusoidal capillarization in liver cirrhosis and hepatocellular carcinoma rat model via the MK/integrin signaling pathway.
Integrin β1/FAK/SRC signal pathway is involved in autism spectrum disorder in Tspan7 knockout rats.
Dimethyl fumarate possesses antiplatelet and antithrombotic properties.
Loss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development.
Integrin β6 mediates epithelial-mesenchymal transition in diabetic kidney disease.
Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells.
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
Hypoglycemia-Exacerbated Mitochondrial Connexin 43 Accumulation Aggravates Cardiac Dysfunction in Diabetic Cardiomyopathy.
Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H(2)O(2)-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Estrogen receptor variant ER-α36 facilitates estrogen signaling via EGFR in glioblastoma.
Maizediterpene D from the roots of Zea mays L. alleviates hydrogen peroxide induced oxidative stress and improves cell survival by activation of TrkB/IGF-1R crosstalk pathways.
Strategies to Attenuate Myocardial Infarction and No-Reflow Through Preservation of Vascular Integrity by Pigment Epithelium-Derived Factor.
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis.
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
TNFSF9 promotes metastasis of pancreatic cancer by regulating M2 polarization of macrophages through Src/FAK/p-Akt/IL-1β signaling.
Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer.
Angiopoietin2-mediated caveolin1 phosphorylation regulating transcytosis of renal tubular epithelial cell contributes to the occurrence of albuminuria under high glucose exposure.
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
The Synaptic Vesicle Protein 2A Interacts With Key Pathogenic Factors in Alzheimer's Disease: Implications for Treatment.
Inhibition of Phosphodiesterase 5 Promotes the Aromatase-Mediated Estrogen Biosynthesis in Osteoblastic Cells by Activation of cGMP/PKG/SHP2 Pathway.
Identification of a Novel Ferroptosis-Related Gene Prognostic Signature in Bladder Cancer.
A network pharmacology strategy to investigate the anti-osteoarthritis mechanism of main lignans components of Schisandrae Fructus.
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling.
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Protein tyrosine phosphatase 1B(PTP1B) promotes melanoma cells progression through Src activation.
Qihuzha granule attenuated LPS-induced acute spleen injury in mice via Src/MAPK/Stat3 signal pathway.
Quantitative proteomics revealed modulation of macrophages by MetQ gene of Streptococcus suis serotype 2.
Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression.
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling.
A non-canonical rhodopsin-mediated insulin receptor signaling pathway in retinal photoreceptor neurons.
SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis.
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
TRIM50 acts as a novel Src suppressor and inhibits ovarian cancer progression.
Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.
DR region specific antibody ameliorated but ouabain worsened renal injury in nephrectomized rats through regulating Na,K-ATPase mediated signaling pathways.
NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis.
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na(+)-K(+)-ATPase, inhibiting Na(+)-K(+)-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.
Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability.
Dioscin Inhibits HSC-T6 Cell Migration via Adjusting SDC-4 Expression: Insights from iTRAQ-Based Quantitative Proteomics.
PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.
Regulation of Na(+)-K(+)-ATPase effected high glucose-induced myocardial cell injury through c-Src dependent NADPH oxidase/ROS pathway.
Activation of Na(+)-K(+)-ATPase with DRm217 attenuates oxidative stress-induced myocardial cell injury via closing Na(+)-K(+)-ATPase/Src/Ros amplifier.
Extracellular matrix protein ITGBL1 promotes ovarian cancer cell migration and adhesion through Wnt/PCP signaling and FAK/SRC pathway.
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Gefitinib enhances oxaliplatin-induced apoptosis mediated by Src and PKC-modulated gap junction function.
Paper-based microreactor array for rapid screening of cell signaling cascades.
Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergence.
Mechanisms of growth-promoting and tumor-protecting effects of epithelial nicotinic acetylcholine receptors.
Histochemical evidence of zoledronate inhibiting c-src expression and interfering with CD44/OPN-mediated osteoclast adhesion in the tibiae of mice.
EphB2 contributes to human naive B-cell activation and is regulated by miR-185.
Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
Phosphorylated Syk expression is enhanced in Nasu-Hakola disease brains.
Wang C, Cui L, Tantai M, Feng G, Cai Z, Feng Y
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 17;
Naunyn-Schmiedeberg's archives of pharmacology 2026 Mar 17;
Network pharmacology prediction and experimental validation to explore the potential mechanism of Danggui Shaoyao San against Acute Kidney Injury.
Xiao C, Wang P, Wang Y, Zhu J, Zhu H, Li X, Wang R
Journal of ethnopharmacology 2026 Jan 10;354:120540
Journal of ethnopharmacology 2026 Jan 10;354:120540
Anti-NSCLC efficacy of a novel ROR1/PI3Kα/BRD4 multi-target inhibitor.
Zhong T, Lee JY, Li Q, Luo F, Xiong L, Wang R, Liu J, Su M, Tang L, Lee SK, Fan Y
Bioorganic & medicinal chemistry 2026 Jan 1;132:118483
Bioorganic & medicinal chemistry 2026 Jan 1;132:118483
P2Y2 receptor as a favorable predictor of gastric cancer.
Wu YQ, Wang WL
Tissue & cell 2026 Apr;99:103278
Tissue & cell 2026 Apr;99:103278
EMP2 promotes hepatocellular carcinoma proliferation and invasion by activating cellular autophagy.
Pang H, Wu F, Zhang YU, Zhang N, Wang C, Li Q, He GU, Zhang P
Oncology research 2025;33(2):443-464
Oncology research 2025;33(2):443-464
Galangin reduces MPTP-induced dopamine neuron injury via the autophagy dependent-PI3K/AKT pathway.
Huang L, Li Q, Wu J, He Y, Huang J, Xie S, Yang C, Ruan Q, Zhou Z, Deng M
Frontiers in aging neuroscience 2025;17:1568002
Frontiers in aging neuroscience 2025;17:1568002
KLK8/HGF/Met signaling pathway mediates diabetes-associated hippocampal neuroinflammation in male mice.
Xu DH, Zhang XY, Liu SY, Wei J, Zhan JH, Du JK, Liu YJ, Zhu XY
Theranostics 2025;15(13):6290-6312
Theranostics 2025;15(13):6290-6312
Ellagic Acid-Loaded sEVs Encapsulated in GelMA Hydrogel Accelerate Diabetic Wound Healing by Activating EGFR on Skin Repair Cells.
Tian L, Wang Z, Chen S, Guo K, Hao Y, Ma L, Ma K, Chen J, Liu X, Li L, Fu X, Zhang C
Cell proliferation 2025 Oct;58(10):e70064
Cell proliferation 2025 Oct;58(10):e70064
HOMER3 orchestrates SRC-YAP1 activity that promotes tumor cell growth and antagonizes anti-tumor immunotherapy in prostate cancer.
Tong T, Lei H, Huang M, Yang Z, Dai X, Zou H, Guo Y, Luo J, Teng Q, Cao F, Pang J, Li P
Oncogene 2025 Oct;44(41):3895-3908
Oncogene 2025 Oct;44(41):3895-3908
The E3 ubiquitin ligase TRIM56 promotes aggregation and activation of Src protein through Lys63-linked polyubiquitination in hepatocellular carcinoma.
Zhu L, Cui X, Xu H, Yang M, Han L
Cell death & disease 2025 Oct 16;16(1):731
Cell death & disease 2025 Oct 16;16(1):731
Effective-compounds of Jinshui Huanxian Formula acts as an SRC inhibitor to inhibit HK2-mediated H3K18 lactation and improve pulmonary fibrosis.
Zheng J, Du Y, Shao W, Li J, Zhao P, Zhang Q
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156628
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 May;140:156628
Spike proteins of coronaviruses activate mast cells for degranulation via stimulating Src/PI3K/AKT/Ca(2+) intracellular signaling cascade.
Zhang S, Xu C-L, Wang J, Xiong X, Wang J-H
Journal of virology 2025 May 20;99(5):e0007825
Journal of virology 2025 May 20;99(5):e0007825
Penta-1,4-dien-3-one and quinoxaline conjugates as potential anticancer agents via inhibiting EphB3/SRC/AKT axis.
Li Q, Zhou M, Yang Y, Jiang Y, Chen C, Hu E, Chen J, Wang D
Life sciences 2025 May 1;368:123510
Life sciences 2025 May 1;368:123510
Integrin β3 N125 glycosylation is essential for human cytomegalovirus entry into fibroblasts.
Zheng L, Pan T, Wang H, He Z, Tian J
International journal of biological macromolecules 2025 Jun;313:144322
International journal of biological macromolecules 2025 Jun;313:144322
Tripterygium wilfordii polyglycoside tablets attenuated the progression of hepatocellular carcinoma by targeting IL-6 and downstream signaling pathways in a multi-target manner.
Ren PY, Zhang JY, Zhao L, Sun XJ
Journal of Asian natural products research 2025 Jun;27(6):929-949
Journal of Asian natural products research 2025 Jun;27(6):929-949
Network pharmacology and in vitro analyses reveal EGCG inhibits breast cancer progression via suppression of the EGFR/Src pathway.
Liu H, Li Z, Xu X, Xu B, Li Z
Biochemical and biophysical research communications 2025 Jul 8;769:151942
Biochemical and biophysical research communications 2025 Jul 8;769:151942
A new specific GluN2B partial antagonist ameliorates brain injury caused by ischemic stroke in rats.
Fan Y, Wu H, Yin D, Liu Q, Yuan C, Zhong T, Xia B, Xiong L, Li Y, Zeng L, Li Y, Li Y, Tang L
Bioorganic chemistry 2025 Jul 1;161:108547
Bioorganic chemistry 2025 Jul 1;161:108547
Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy.
Liu N, Zhao P, Cao P, Hui J, Pan Y, Cheng J
BMC gastroenterology 2025 Jan 29;25(1):44
BMC gastroenterology 2025 Jan 29;25(1):44
MTHFD2 promotes osteoclastogenesis and bone loss in rheumatoid arthritis by enhancing CKMT1-mediated oxidative phosphorylation.
Li Y, Cai M, Qin Y, Dai X, Liang L, Li Z, Wen X, Jin H, Yang C, Chen Z
BMC medicine 2025 Feb 27;23(1):124
BMC medicine 2025 Feb 27;23(1):124
RhoB regulates prostate cancer cell proliferation and docetaxel sensitivity via the PI3K-AKT signaling pathway.
Sheng T, Su H, Yao L, Qu Z, Liu H, Shao W, Zhang X
BMC cancer 2025 Feb 26;25(1):354
BMC cancer 2025 Feb 26;25(1):354
Magnolol preserves the integrity of the intestinal epithelial barrier and mitigates intestinal injury through activation of PPAR γ in COPD rat.
Tao L, Zhang Q, Liu L, Wang K, Liu X, Li J, Zhao P
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119068
Journal of ethnopharmacology 2025 Feb 10;338(Pt 2):119068
Tenvermectin B, a novel macrocyclic lactone antibiotic, suppresses glioblastoma progression by targeting RhoJ.
Nie C, Liang H, Zhou J, Liu H, Shang R, Yang H, Jiang W, Qi H, Wang J, Gao A
Cellular signalling 2025 Dec;136:112117
Cellular signalling 2025 Dec;136:112117
Cancer-associated fibroblast-derived fibulin-5 promotes radioresistance in non-small-cell lung cancer.
Zhang R, Yan W, Yuan J, Ma Y, Ren Z, Chen X, Lv J, Wu M, Yu J, Chen D
Cell reports 2025 Aug 26;44(8):116018
Cell reports 2025 Aug 26;44(8):116018
ICAM-1-mediated Src signaling pathway plays a pivotal role in encephalomyocarditis virus entry.
Lian R, Dou X, Wang N, Li S, Xie J, Li X, Yang Y, Wen Y, Li H, Feng R
Journal of virology 2025 Aug 19;99(8):e0071525
Journal of virology 2025 Aug 19;99(8):e0071525
Transferrin receptor 1 (TfR1) functions as an entry receptor for scale drop disease virus to invade the host cell via clathrin-mediated endocytosis.
Chen J, Fu Y, Li Y, Weng S, Wang H, He J, Dong C
Journal of virology 2025 Aug 19;99(8):e0067125
Journal of virology 2025 Aug 19;99(8):e0067125
Combining RNA-seq, molecular docking and experimental verification to explore the mechanism of BAM15 as a potential drug for atherosclerosis.
Ma M, Zhong J, Tai Y, Xu S, Pei Z, Wang X
Scientific reports 2025 Apr 17;15(1):13347
Scientific reports 2025 Apr 17;15(1):13347
Dual-Multivalent Aptamer-Based Drug Delivery Platform for Targeted SRC Silencing to Enhance Doxorubicin Sensitivity in Endometrial Cancer.
Li H, Cheng S, Zhang Q, Zhou T, Zhang T, Liu S, Peng Y, Yu J, Xu J, Wang Q, Zhang J, Yao Y, Wang H
International journal of biological sciences 2024;20(15):5812-5830
International journal of biological sciences 2024;20(15):5812-5830
Modified Gegen Qinlian Decoction modulated the gut microbiome and bile acid metabolism and restored the function of goblet cells in a mouse model of ulcerative colitis.
Huang J, Zhang J, Wang F, Tang X
Frontiers in immunology 2024;15:1445838
Frontiers in immunology 2024;15:1445838
Pan-cancer analysis predict that FAT1 is a therapeutic target and immunotherapy biomarker for multiple cancer types including non-small cell lung cancer.
Ding C, Huang H, Wu D, Chen C, Hua Y, Liu J, Li Y, Liu H, Chen J
Frontiers in immunology 2024;15:1369073
Frontiers in immunology 2024;15:1369073
Hinesol attenuates DSS-induced ulcerative colitis through the suppression of Src-mediated NF-κB and chemokine signaling pathway.
Li YX, Liu J, Li F
Cell biochemistry and biophysics 2024 Sep;82(3):2747-2757
Cell biochemistry and biophysics 2024 Sep;82(3):2747-2757
NAMPT enhances LOX expression and promotes metastasis in human chondrosarcoma cells by inhibiting miR-26b-5p synthesis.
Lin CY, Law YY, Yu CC, Wu YY, Hou SM, Chen WL, Yang SY, Tsai CH, Lo YS, Fong YC, Tang CH
Journal of cellular physiology 2024 Sep;239(9):e31345
Journal of cellular physiology 2024 Sep;239(9):e31345
CircSEC24B activates autophagy and induces chemoresistance of colorectal cancer via OTUB1-mediated deubiquitination of SRPX2.
Wang D, Li Y, Chang W, Feng M, Yang Y, Zhu X, Liu Z, Fu Y
Cell death & disease 2024 Sep 27;15(9):693
Cell death & disease 2024 Sep 27;15(9):693
Modulation of SRC by SNTB1 activates the Hippo-YAP pathway during colon adenocarcinoma metastasis.
Chang Z, Huang R, Song J, Li Z, Pi M, Xian S, Zhang J, Huang J, Xie R, Ji G, Han D, Huang Q
Journal of translational medicine 2024 Nov 15;22(1):1029
Journal of translational medicine 2024 Nov 15;22(1):1029
Quercetin improves the protection of hydroxysafflor yellow a against cerebral ischemic injury by modulating of blood-brain barrier and src-p-gp-mmp-9 signalling.
Li X, Yang Y, Feng P, Wang H, Zheng M, Zhu Y, Zhong K, Hu J, Ye Y, Lu L, Zhao Q
Heliyon 2024 May 30;10(10):e31002
Heliyon 2024 May 30;10(10):e31002
RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia.
Zhao M, Dai B, Li X, Zhang Y, Qiao C, Qin Y, Li Z, Li Q, Wang S, Yang Y, Chen Y
eLife 2024 Jun 12;12
eLife 2024 Jun 12;12
Erythroid-intrinsic activation of TLR8 impairs erythropoiesis in inherited anemia.
Liang J, Wan Y, Gao J, Zheng L, Wang J, Wu P, Li Y, Wang B, Wang D, Ma Y, Shen B, Lv X, Wang D, An N, Ma X, Geng G, Tong J, Liu J, Chen G, Gao M, Kurita R, Nakamura Y, Zhu P, Yin H, Zhu X, Shi L
Nature communications 2024 Jul 6;15(1):5678
Nature communications 2024 Jul 6;15(1):5678
Curcumin suppresses metastasis, invasion, and proliferation in osteosarcoma cells by regulating the EGFR/Src signaling axis.
Liu H, Li Z, Xu B, Li Z, Yang X, Luo J
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241308082
International journal of immunopathology and pharmacology 2024 Jan-Dec;38:3946320241308082
Hesperetin promotes bladder cancer cells death via the PI3K/AKT pathway by network pharmacology and molecular docking.
Lv Y, Liu Z, Deng L, Xia S, Mu Q, Xiao B, Xiu Y, Liu Z
Scientific reports 2024 Jan 10;14(1):1009
Scientific reports 2024 Jan 10;14(1):1009
Adaptor protein CEMIP reduces the chemosensitivity of small cell lung cancer via activation of an SRC-YAP oncogenic module.
Shen XJ, Wei HL, Mo XC, Mo XX, Li L, He JC, Wei XY, Qin XJ, Xing SP, Luo Z, Chen ZQ, Yang J
Acta pharmacologica Sinica 2024 Dec;45(12):2657-2671
Acta pharmacologica Sinica 2024 Dec;45(12):2657-2671
Cyberpharmacology uncover the mechanism of the total Rhizoma Coptidis extracts ameliorate chronic atrophic gastritis.
Ma Z, Chen X, Xiong M, Wang H, Sun C, Tang W, Li J, Li X, Ma H, Ye X
Journal of ethnopharmacology 2024 Dec 5;335:118644
Journal of ethnopharmacology 2024 Dec 5;335:118644
Fraxin represses NF-κB pathway via inhibiting the activation of epidermal growth factor receptor to ameliorate diabetic renal tubulointerstitial fibrosis.
Zeng J, Liang L, Chen R, Li C, Pan L, Wen M, Lv D, Liu M, Xu Z, Huang H
European journal of pharmacology 2023 Sep 15;955:175915
European journal of pharmacology 2023 Sep 15;955:175915
Network pharmacology integrated with experimental validation revealed potential molecular mechanisms of Camellia nitidissima C. W. Chi in the treatment of lung cancer.
Zhou A, Zhou C, Wang D, Qian M, Huang L
Journal of ethnopharmacology 2023 Oct 5;314:116576
Journal of ethnopharmacology 2023 Oct 5;314:116576
Dahuang Zhechong pill attenuates hepatic sinusoidal capillarization in liver cirrhosis and hepatocellular carcinoma rat model via the MK/integrin signaling pathway.
Fu C, Zhang Y, Xi WJ, Xu K, Meng F, Ma T, Li W, Wu L, Chen Z
Journal of ethnopharmacology 2023 May 23;308:116191
Journal of ethnopharmacology 2023 May 23;308:116191
Integrin β1/FAK/SRC signal pathway is involved in autism spectrum disorder in Tspan7 knockout rats.
Pang S, Luo Z, Dong W, Gao S, Chen W, Liu N, Zhang X, Gao X, Li J, Gao K, Shi X, Guan F, Zhang L, Zhang L
Life science alliance 2023 Mar;6(3)
Life science alliance 2023 Mar;6(3)
Dimethyl fumarate possesses antiplatelet and antithrombotic properties.
Chu X, Zhang J, Li Y, Yuan K, Wang X, Gui X, Sun Y, Geng C, Ju W, Xu M, Li Z, Zeng L, Xu K, Qiao J
International immunopharmacology 2023 Jul;120:110381
International immunopharmacology 2023 Jul;120:110381
Loss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development.
Dai H, Xu W, Wang L, Li X, Sheng X, Zhu L, Li Y, Dong X, Zhou W, Han C, Mao Y, Yao L
Breast cancer research : BCR 2023 Jul 28;25(1):90
Breast cancer research : BCR 2023 Jul 28;25(1):90
Integrin β6 mediates epithelial-mesenchymal transition in diabetic kidney disease.
Li X, Miao Y, Li T, Liu X, Xu L, Guo J, Yu X, Sun B, Zhu Y, Ai D, Chen L
Molecular and cellular endocrinology 2023 Jul 15;572:111955
Molecular and cellular endocrinology 2023 Jul 15;572:111955
Alkaloids from Piper longum Exhibit Anti-inflammatory Activity and Synergistic Effects with Chemotherapeutic Agents against Cervical Cancer Cells.
Wan Q, Xu J, Zhu C, Liu X, Tu Y, Lei J, Yu J
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10349-10360
Journal of agricultural and food chemistry 2023 Jul 12;71(27):10349-10360
Verniciflavanol A, a profisetinidin-type-4-arylflavan-3-ol from toxicodendron vernicifluum protects SH-SY5Y cells against H2O2-Induced oxidative stress.
Li M, Zhang Y, Han T, Guan L, Fan D, Wu Q, Liu J, Xu Y, Fan Y
Phytochemistry 2023 Jan;205:113487
Phytochemistry 2023 Jan;205:113487
Nodakenin alleviates ovariectomy-induced osteoporosis by modulating osteoblastogenesis and osteoclastogenesis.
Liu C, Zhao M, Chen J, Xu L, Wang K, Li G
European journal of pharmacology 2023 Dec 5;960:176121
European journal of pharmacology 2023 Dec 5;960:176121
Hypoglycemia-Exacerbated Mitochondrial Connexin 43 Accumulation Aggravates Cardiac Dysfunction in Diabetic Cardiomyopathy.
Wei X, Chang ACH, Chang H, Xu S, Xue Y, Zhang Y, Lei M, Chang ACY, Zhang Q
Frontiers in cardiovascular medicine 2022;9:800185
Frontiers in cardiovascular medicine 2022;9:800185
Spheroid Formation Enhances the Regenerative Capacity of Nucleus Pulposus Cells via Regulating N-CDH and ITGβ1 Interaction.
Wang Y, Wang H, Zhuo Y, Hu Y, Li X, Xu Y, Sun B, Liu M, Zou L, Liu L, Luo L, Zhao C, Li P, Zhou Q
International journal of biological sciences 2022;18(9):3676-3696
International journal of biological sciences 2022;18(9):3676-3696
Design, Synthesis and Evaluation of Novel 1,4-Disubstituted Piperazine-2,5-dione Derivatives as Antioxidants against H(2)O(2)-Induced Oxidative Injury via the IL-6/Nrf2 Loop Pathway.
Xiong L, Wu H, Zhong T, Luo F, Li Q, Li M, Fan Y
Antioxidants (Basel, Switzerland) 2022 Oct 12;11(10)
Antioxidants (Basel, Switzerland) 2022 Oct 12;11(10)
Estrogen receptor variant ER-α36 facilitates estrogen signaling via EGFR in glioblastoma.
Qu C, Wang C, Li H, Li Y, Han C, Tao X, Guan X, Zhang Y, Chen M, Liu J, Zou W
Cell biology international 2022 Nov;46(11):1759-1774
Cell biology international 2022 Nov;46(11):1759-1774
Maizediterpene D from the roots of Zea mays L. alleviates hydrogen peroxide induced oxidative stress and improves cell survival by activation of TrkB/IGF-1R crosstalk pathways.
Fan Y, Wu H, Xiong L, Luo F, Li Q, Wang D, Zhong T
Fitoterapia 2022 Nov;163:105314
Fitoterapia 2022 Nov;163:105314
Strategies to Attenuate Myocardial Infarction and No-Reflow Through Preservation of Vascular Integrity by Pigment Epithelium-Derived Factor.
Zhang H, Li Z, Quan X, Liu X, Sun T, Wei T, Pan J, Liu Z, Wang M, Dong H, Zhang Z
Human gene therapy 2022 Mar;33(5-6):330-345
Human gene therapy 2022 Mar;33(5-6):330-345
Novel Flavan-3,4-diol vernicidin B from Toxicodendron Vernicifluum (Anacardiaceae) as potent antioxidant via IL-6/Nrf2 cross-talks pathways.
Zhong T, Li M, Wu H, Wang D, Liu J, Xu Y, Fan Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154041
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154041
Amino acid catabolism regulates hematopoietic stem cell proteostasis via a GCN2-eIF2α axis.
Li C, Wu B, Li Y, Chen J, Ye Z, Tian X, Wang J, Xu X, Pan S, Zheng Y, Cai X, Jiang L, Zhao M
Cell stem cell 2022 Jul 7;29(7):1119-1134.e7
Cell stem cell 2022 Jul 7;29(7):1119-1134.e7
N-glycosylation of GDF15 abolishes its inhibitory effect on EGFR in AR inhibitor-resistant prostate cancer cells.
Wang R, Wen P, Yang G, Feng Y, Mi Y, Wang X, Zhu S, Chen YQ
Cell death & disease 2022 Jul 19;13(7):626
Cell death & disease 2022 Jul 19;13(7):626
TNFSF9 promotes metastasis of pancreatic cancer by regulating M2 polarization of macrophages through Src/FAK/p-Akt/IL-1β signaling.
Wu J, Wang Y, Yang Y, Liu F, Jiang Z, Jiang Z
International immunopharmacology 2022 Jan;102:108429
International immunopharmacology 2022 Jan;102:108429
Intracellular CYTL1, a novel tumor suppressor, stabilizes NDUFV1 to inhibit metabolic reprogramming in breast cancer.
Xue W, Li X, Li W, Wang Y, Jiang C, Zhou L, Gao J, Yu Y, Shen Y, Xu Q
Signal transduction and targeted therapy 2022 Feb 4;7(1):35
Signal transduction and targeted therapy 2022 Feb 4;7(1):35
Angiopoietin2-mediated caveolin1 phosphorylation regulating transcytosis of renal tubular epithelial cell contributes to the occurrence of albuminuria under high glucose exposure.
Liu J, Yao J, Zhao Y, Su J, Ye J, Wang Y
Journal of translational medicine 2022 Apr 25;20(1):185
Journal of translational medicine 2022 Apr 25;20(1):185
lncRNA Gm16410 Mediates PM(2).(5)-Induced Macrophage Activation via PI3K/AKT Pathway.
Xu J, Xu H, Ma K, Wang Y, Niu B, Zhang L, Li F
Frontiers in cell and developmental biology 2021;9:618045
Frontiers in cell and developmental biology 2021;9:618045
The Synaptic Vesicle Protein 2A Interacts With Key Pathogenic Factors in Alzheimer's Disease: Implications for Treatment.
Kong Y, Huang L, Li W, Liu X, Zhou Y, Liu C, Zhang S, Xie F, Zhang Z, Jiang D, Zhou W, Ni R, Zhang C, Sun B, Wang J, Guan Y
Frontiers in cell and developmental biology 2021;9:609908
Frontiers in cell and developmental biology 2021;9:609908
Inhibition of Phosphodiesterase 5 Promotes the Aromatase-Mediated Estrogen Biosynthesis in Osteoblastic Cells by Activation of cGMP/PKG/SHP2 Pathway.
Wisanwattana W, Wongkrajang K, Cao DY, Shi XK, Zhang ZH, Zhou ZY, Li F, Mei QG, Wang C, Suksamrarn A, Zhang GL, Wang F
Frontiers in endocrinology 2021;12:636784
Frontiers in endocrinology 2021;12:636784
Identification of a Novel Ferroptosis-Related Gene Prognostic Signature in Bladder Cancer.
Sun J, Yue W, You J, Wei X, Huang Y, Ling Z, Hou J
Frontiers in oncology 2021;11:730716
Frontiers in oncology 2021;11:730716
A network pharmacology strategy to investigate the anti-osteoarthritis mechanism of main lignans components of Schisandrae Fructus.
Min L, Wu Y, Cao G, Mi D, Chen C
International immunopharmacology 2021 Sep;98:107873
International immunopharmacology 2021 Sep;98:107873
Silencing ZIC2 abrogates tumorigenesis and anoikis resistance of non-small cell lung cancer cells by inhibiting Src/FAK signaling.
Liu A, Xie H, Li R, Ren L, Yang B, Dai L, Lu W, Liu B, Ren D, Zhang X, Chen Q, Huang Y, Shi K
Molecular therapy oncolytics 2021 Sep 24;22:195-208
Molecular therapy oncolytics 2021 Sep 24;22:195-208
TNFSF9 promotes metastasis of pancreatic cancer through Wnt/Snail signaling and M2 polarization of macrophages.
Wu J, Wang Y, Yang Y, Liu F, Chen J, Jiang Z, Jiang Z
Aging 2021 Sep 13;13(17):21571-21586
Aging 2021 Sep 13;13(17):21571-21586
Salvianolic acid A prevented cerebrovascular endothelial injury caused by acute ischemic stroke through inhibiting the Src signaling pathway.
Liu CD, Liu NN, Zhang S, Ma GD, Yang HG, Kong LL, Du GH
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
Acta pharmacologica Sinica 2021 Mar;42(3):370-381
A network-based analysis and experimental validation of traditional Chinese medicine Yuanhu Zhitong Formula in treating neuropathic pain.
Liu T, Li T, Chen X, Zhang K, Li M, Yao W, Zhang C, Wan L
Journal of ethnopharmacology 2021 Jun 28;274:114037
Journal of ethnopharmacology 2021 Jun 28;274:114037
VEGF/Src signaling mediated pleural barrier damage and increased permeability contributes to subpleural pulmonary fibrosis.
Lu YZ, Liang LM, Cheng PP, Xiong L, Wang M, Song LJ, Yu F, He XL, Xiong L, Wang XR, Xin JB, Ye H, Ma WL
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
American journal of physiology. Lung cellular and molecular physiology 2021 Jun 1;320(6):L990-L1004
Protein tyrosine phosphatase 1B(PTP1B) promotes melanoma cells progression through Src activation.
Wang Q, Pan Y, Zhao L, Qi F, Liu J
Bioengineered 2021 Dec;12(1):8396-8406
Bioengineered 2021 Dec;12(1):8396-8406
Qihuzha granule attenuated LPS-induced acute spleen injury in mice via Src/MAPK/Stat3 signal pathway.
Zhong T, Feng M, Su M, Wang D, Li Q, Jia S, Luo F, Wang H, Hu E, Yang X, Fan Y
Journal of ethnopharmacology 2021 Dec 5;281:114458
Journal of ethnopharmacology 2021 Dec 5;281:114458
Quantitative proteomics revealed modulation of macrophages by MetQ gene of Streptococcus suis serotype 2.
Pei X, Liu J, Liu M, Zhou H, Wang X, Fan H
AMB Express 2020 Oct 30;10(1):195
AMB Express 2020 Oct 30;10(1):195
Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression.
Du L, Li CR, He QF, Li XH, Yang LF, Zou Y, Yang ZX, Zhang D, Xing XW
Molecular medicine (Cambridge, Mass.) 2020 Oct 27;26(1):96
Molecular medicine (Cambridge, Mass.) 2020 Oct 27;26(1):96
Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes.
Han P, Hanlon D, Arshad N, Lee JS, Tatsuno K, Robinson E, Filler R, Sobolev O, Cote C, Rivera-Molina F, Toomre D, Fahmy T, Edelson R
Science advances 2020 Mar;6(11):eaaz1580
Science advances 2020 Mar;6(11):eaaz1580
The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
Zhu L, Qin C, Li T, Ma X, Qiu Y, Lin Y, Ma D, Qin Z, Sun C, Shen X, Zhao Y, Han L
Cell death and differentiation 2020 Jun;27(6):1819-1831
Cell death and differentiation 2020 Jun;27(6):1819-1831
Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling.
Dong M, Xiao Q, Hu J, Cheng F, Zhang P, Zong W, Tang Q, Li X, Mao F, He Y, Yu X, Wan F, Lei T, Guo D, Wang B
Cancer gene therapy 2020 Dec;27(12):878-897
Cancer gene therapy 2020 Dec;27(12):878-897
A non-canonical rhodopsin-mediated insulin receptor signaling pathway in retinal photoreceptor neurons.
Rajala A, Rajala RVS
Cell biology international 2020 Apr;44(4):1020-1027
Cell biology international 2020 Apr;44(4):1020-1027
SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis.
Liu R, Shuai Y, Luo J, Zhang Z
Frontiers in oncology 2019;9:1035
Frontiers in oncology 2019;9:1035
Antimetastatic Effect of Fucoidan-Sargassum against Liver Cancer Cell Invadopodia Formation via Targeting Integrin αVβ3 and Mediating αVβ3/Src/E2F1 Signaling.
Pan TJ, Li LX, Zhang JW, Yang ZS, Shi DM, Yang YK, Wu WZ
Journal of Cancer 2019;10(20):4777-4792
Journal of Cancer 2019;10(20):4777-4792
TRIM50 acts as a novel Src suppressor and inhibits ovarian cancer progression.
Qiu Y, Liu P, Ma X, Ma X, Zhu L, Lin Y, You Y, Yu W, Ma D, Sun C, Qin Z, Zhao Y, Shi J, Han L
Biochimica et biophysica acta. Molecular cell research 2019 Sep;1866(9):1412-1420
Biochimica et biophysica acta. Molecular cell research 2019 Sep;1866(9):1412-1420
Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.
Wang W, Wang M, Ruan Y, Tan J, Wang H, Yang T, Li J, Zhou Q
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10097-10106
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10097-10106
DR region specific antibody ameliorated but ouabain worsened renal injury in nephrectomized rats through regulating Na,K-ATPase mediated signaling pathways.
Wang J, Ullah SH, Li M, Zhang M, Zhang F, Zheng J, Yan X
Aging 2019 Feb 26;11(4):1151-1162
Aging 2019 Feb 26;11(4):1151-1162
NLRP3 regulates platelet integrin αIIbβ3 outside-in signaling, hemostasis and arterial thrombosis.
Qiao J, Wu X, Luo Q, Wei G, Xu M, Wu Y, Liu Y, Li X, Zi J, Ju W, Fu L, Chen C, Wu Q, Zhu S, Qi K, Li D, Li Z, Andrews RK, Zeng L, Gardiner EE, Xu K
Haematologica 2018 Sep;103(9):1568-1576
Haematologica 2018 Sep;103(9):1568-1576
Hypoxia-Inducible Factor-1α (HIF-1α) Expression on Endothelial Cells in Juvenile Nasopharyngeal Angiofibroma: A Review of 70 cases and Tissue Microarray Analysis.
Song X, Yang C, Zhang H, Wang J, Sun X, Hu L, Liu Z, Wang D
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
The Annals of otology, rhinology, and laryngology 2018 Jun;127(6):357-366
DRm217 attenuates myocardial ischemia-reperfusion injury via stabilizing plasma membrane Na(+)-K(+)-ATPase, inhibiting Na(+)-K(+)-ATPase/ROS pathway and activating PI3K/Akt and ERK1/2.
Yan X, Xun M, Wu L, Du X, Zhang F, Zheng J
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Toxicology and applied pharmacology 2018 Jun 15;349:62-71
Hypoxia Activates Src and Promotes Endocytosis Which Decreases MMP-2 Activity and Aggravates Renal Interstitial Fibrosis.
Cheng Z, Liu L, Wang Z, Cai Y, Xu Q, Chen P
International journal of molecular sciences 2018 Feb 15;19(2)
International journal of molecular sciences 2018 Feb 15;19(2)
ANXA2 promotes esophageal cancer progression by activating MYC-HIF1A-VEGF axis.
Ma S, Lu CC, Yang LY, Wang JJ, Wang BS, Cai HQ, Hao JJ, Xu X, Cai Y, Zhang Y, Wang MR
Journal of experimental & clinical cancer research : CR 2018 Aug 6;37(1):183
Journal of experimental & clinical cancer research : CR 2018 Aug 6;37(1):183
Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability.
Liu H, Li D, Liu S, Liu Z, Li M
Histochemistry and cell biology 2018 Apr;149(4):343-351
Histochemistry and cell biology 2018 Apr;149(4):343-351
Dioscin Inhibits HSC-T6 Cell Migration via Adjusting SDC-4 Expression: Insights from iTRAQ-Based Quantitative Proteomics.
Yin L, Qi Y, Xu Y, Xu L, Han X, Tao X, Song S, Peng J
Frontiers in pharmacology 2017;8:665
Frontiers in pharmacology 2017;8:665
PALLD Regulates Phagocytosis by Enabling Timely Actin Polymerization and Depolymerization.
Sun HM, Chen XL, Chen XJ, Liu J, Ma L, Wu HY, Huang QH, Xi XD, Yin T, Zhu J, Chen Z, Chen SJ
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1817-1826
Journal of immunology (Baltimore, Md. : 1950) 2017 Sep 1;199(5):1817-1826
Regulation of Na(+)-K(+)-ATPase effected high glucose-induced myocardial cell injury through c-Src dependent NADPH oxidase/ROS pathway.
Yan X, Xun M, Dou X, Wu L, Han Y, Zheng J
Experimental cell research 2017 Aug 15;357(2):243-251
Experimental cell research 2017 Aug 15;357(2):243-251
Activation of Na(+)-K(+)-ATPase with DRm217 attenuates oxidative stress-induced myocardial cell injury via closing Na(+)-K(+)-ATPase/Src/Ros amplifier.
Yan X, Xun M, Dou X, Wu L, Zhang F, Zheng J
Apoptosis : an international journal on programmed cell death 2017 Apr;22(4):531-543
Apoptosis : an international journal on programmed cell death 2017 Apr;22(4):531-543
Extracellular matrix protein ITGBL1 promotes ovarian cancer cell migration and adhesion through Wnt/PCP signaling and FAK/SRC pathway.
Sun L, Wang D, Li X, Zhang L, Zhang H, Zhang Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Jul;81:145-151
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016 Jul;81:145-151
Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation.
Zheng J, Huang X, Tan W, Yu D, Du Z, Chang J, Wei L, Han Y, Wang C, Che X, Zhou Y, Miao X, Jiang G, Yu X, Yang X, Cao G, Zuo C, Li Z, Wang C, Cheung ST, Jia Y, Zheng X, Shen H, Wu C, Lin D
Nature genetics 2016 Jul;48(7):747-57
Nature genetics 2016 Jul;48(7):747-57
Gefitinib enhances oxaliplatin-induced apoptosis mediated by Src and PKC-modulated gap junction function.
Wu JF, Ji J, Dong SY, Li BB, Yu ML, Wu DD, Tao L, Tong XH
Oncology reports 2016 Dec;36(6):3251-3258
Oncology reports 2016 Dec;36(6):3251-3258
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
Metalloproteinase MT1-MMP islets act as memory devices for podosome reemergence.
El Azzouzi K, Wiesner C, Linder S
The Journal of cell biology 2016 Apr 11;213(1):109-25
The Journal of cell biology 2016 Apr 11;213(1):109-25
Mechanisms of growth-promoting and tumor-protecting effects of epithelial nicotinic acetylcholine receptors.
Chernyavsky AI, Shchepotin IB, Grando SA
International immunopharmacology 2015 Nov;29(1):36-44
International immunopharmacology 2015 Nov;29(1):36-44
Histochemical evidence of zoledronate inhibiting c-src expression and interfering with CD44/OPN-mediated osteoclast adhesion in the tibiae of mice.
Liu H, Cui J, Sun J, Du J, Feng W, Sun B, Li J, Han X, Liu B, Yimin, Oda K, Amizuka N, Li M
Journal of molecular histology 2015 Jun;46(3):313-23
Journal of molecular histology 2015 Jun;46(3):313-23
EphB2 contributes to human naive B-cell activation and is regulated by miR-185.
Yu M, Liang W, Wen S, Zhao T, Zhu MX, Li HH, Long Q, Wang M, Cheng X, Liao YH, Yuan J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Aug;28(8):3609-17
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014 Aug;28(8):3609-17
Microarray analyses reveal liver metastasis-related genes in metastatic colorectal cancer cell model.
Chen Q, Chen L, Zhao R, Yang XD, Imran K, Xing CG
Journal of cancer research and clinical oncology 2013 Jul;139(7):1169-78
Journal of cancer research and clinical oncology 2013 Jul;139(7):1169-78
Phosphorylated Syk expression is enhanced in Nasu-Hakola disease brains.
Satoh J, Tabunoki H, Ishida T, Yagishita S, Jinnai K, Futamura N, Kobayashi M, Toyoshima I, Yoshioka T, Enomoto K, Arai N, Saito Y, Arima K
Neuropathology : official journal of the Japanese Society of Neuropathology 2012 Apr;32(2):149-57
Neuropathology : official journal of the Japanese Society of Neuropathology 2012 Apr;32(2):149-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A431 cells were subjected to SDS PAGE followed by western blot with 11097-1-AP(SRC antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-SRC (IP:11097-1-AP, 5ug; Detection:11097-1-AP 1:1000) with SH-SY5Y cells lysate 2900ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 11097-1-AP(SRC antibody) at dilution of 1:10 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SRC antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SRC. This antibody recognizes human, mouse, rat, hamster antigen. The SRC antibody has been validated for the following applications: ELISA, WB, IHC, IP, FC analysis.
