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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB3435 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3435, RRID:AB_1579911
- Product name
- SRC polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of SRC.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Coexpression of IGF-1R and c-Src proteins in human pancreatic ductal adenocarcinoma.
v-SRC specifically regulates the nucleo-cytoplasmic delocalization of the major isoform of TEL (ETV6).
An increase in the expression and total activity of endogenous p60(c-Src) in several factor-independent mutants of a human GM-CSF-dependent leukemia cell line (TF-1).
Hakam A, Fang Q, Karl R, Coppola D
Digestive diseases and sciences 2003 Oct;48(10):1972-8
Digestive diseases and sciences 2003 Oct;48(10):1972-8
v-SRC specifically regulates the nucleo-cytoplasmic delocalization of the major isoform of TEL (ETV6).
Lopez RG, Carron C, Ghysdael J
The Journal of biological chemistry 2003 Oct 17;278(42):41316-25
The Journal of biological chemistry 2003 Oct 17;278(42):41316-25
An increase in the expression and total activity of endogenous p60(c-Src) in several factor-independent mutants of a human GM-CSF-dependent leukemia cell line (TF-1).
Horn S, Meyer J, Stocking C, Ostertag W, Jücker M
Oncogene 2003 Oct 16;22(46):7170-80
Oncogene 2003 Oct 16;22(46):7170-80
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of SRC polyclonal antibody (Cat # PAB3435) in mouse kidney tissue lysate. SRC (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with SRC polyclonal antibody (Cat # PAB3435) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
