Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- ABIN560922 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Filamin A, alpha (FLNA) (AA 1-838), (full length) antibody
- Antibody type
- Monoclonal
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-838, full length
- Isotype
- IgG
- Antibody clone number
- 4E10-1B2
- Vial size
- 100 μg
- Storage
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Handling
- Aliquot to avoid repeated freezing and thawing.
Submitted references Filamin A is reduced and contributes to the CASR sensitivity in human parathyroid tumors.
Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells.
Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects.
Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells.
Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.
Novel no-stop FLNA mutation causes multi-organ involvement in males.
Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs.
Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes.
Mingione A, Verdelli C, Ferrero S, Vaira V, Guarnieri V, Scillitani A, Vicentini L, Balza G, Beretta E, Terranegra A, Vezzoli G, Soldati L, Corbetta S
Journal of molecular endocrinology 2017 Feb;58(2):91-103
Journal of molecular endocrinology 2017 Feb;58(2):91-103
Fibrinogen-like protein 2/fibroleukin induces long-term allograft survival in a rat model through regulatory B cells.
Bézie S, Picarda E, Tesson L, Renaudin K, Durand J, Ménoret S, Mérieau E, Chiffoleau E, Guillonneau C, Caron L, Anegon I
PloS one 2015;10(3):e0119686
PloS one 2015;10(3):e0119686
Familial periventricular nodular heterotopia, epilepsy and Melnick-Needles Syndrome caused by a single FLNA mutation with combined gain-of-function and loss-of-function effects.
Parrini E, Mei D, Pisanti MA, Catarzi S, Pucatti D, Bianchini C, Mascalchi M, Bertini E, Morrone A, Cavaliere ML, Guerrini R
Journal of medical genetics 2015 Jun;52(6):405-12
Journal of medical genetics 2015 Jun;52(6):405-12
Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells.
Peverelli E, Giardino E, Treppiedi D, Vitali E, Cambiaghi V, Locatelli M, Lasio GB, Spada A, Lania AG, Mantovani G
Endocrinology 2014 Aug;155(8):2932-41
Endocrinology 2014 Aug;155(8):2932-41
Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins.
Sakane A, Alamir Mahmoud Abdallah A, Nakano K, Honda K, Kitamura T, Imoto I, Matsushita N, Sasaki T
Genes to cells : devoted to molecular & cellular mechanisms 2013 Sep;18(9):810-22
Genes to cells : devoted to molecular & cellular mechanisms 2013 Sep;18(9):810-22
Novel no-stop FLNA mutation causes multi-organ involvement in males.
Oegema R, Hulst JM, Theuns-Valks SD, van Unen LM, Schot R, Mancini GM, Schipper ME, de Wit MC, Sibbles BJ, de Coo IF, Nanninga V, Hofstra RM, Halley DJ, Brooks AS
American journal of medical genetics. Part A 2013 Sep;161A(9):2376-84
American journal of medical genetics. Part A 2013 Sep;161A(9):2376-84
Filamin-A is essential for dopamine d2 receptor expression and signaling in tumorous lactotrophs.
Peverelli E, Mantovani G, Vitali E, Elli FM, Olgiati L, Ferrero S, Laws ER, Della Mina P, Villa A, Beck-Peccoz P, Spada A, Lania AG
The Journal of clinical endocrinology and metabolism 2012 Mar;97(3):967-77
The Journal of clinical endocrinology and metabolism 2012 Mar;97(3):967-77
Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes.
Valente EM, Logan CV, Mougou-Zerelli S, Lee JH, Silhavy JL, Brancati F, Iannicelli M, Travaglini L, Romani S, Illi B, Adams M, Szymanska K, Mazzotta A, Lee JE, Tolentino JC, Swistun D, Salpietro CD, Fede C, Gabriel S, Russ C, Cibulskis K, Sougnez C, Hildebrandt F, Otto EA, Held S, Diplas BH, Davis EE, Mikula M, Strom CM, Ben-Zeev B, Lev D, Sagie TL, Michelson M, Yaron Y, Krause A, Boltshauser E, Elkhartoufi N, Roume J, Shalev S, Munnich A, Saunier S, Inglehearn C, Saad A, Alkindy A, Thomas S, Vekemans M, Dallapiccola B, Katsanis N, Johnson CA, Attié-Bitach T, Gleeson JG
Nature genetics 2010 Jul;42(7):619-25
Nature genetics 2010 Jul;42(7):619-25
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA