66886-1-Ig

antibody from Proteintech Group

Targeting: RPS6 S6

Provider product page for 66886-1-Ig

Western blot

ELISA

Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [32]
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Product number: 66886-1-Ig - Provider product page
Provider: Proteintech Group
Product name: RPS6 antibody
Antibody type: Monoclonal
Description: RPS6 antibody (Cat. #66886-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Mouse
Conjugate: Unconjugated
Isotype: IgG
Antibody clone number: 1C3E10
Vial size: 20ul, 150ul

RPS6 protein structure - 66886-1-Ig shown in red.

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Nan X, Zhang S, Chu X, Chen S, Zhang X, Wu Z
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Lin Z, Gao Y, Zhang Q, Yang S, Chen Y, Ding H, Peng W, Zhang X, Nurzat Y, Hu J, Liao W, Xiong B, Xiao M, Zhang X
Cancer letters 2026 May 1;645:218392

PSAT1 inhibits mTORC1 activation by preventing Rag heterodimer formation in lung adenocarcinoma.

Liu Y, Cheng Z, Zhang J, Zhang Y, Zhao T, Sun L, Wen G, Han T, Wang J
Autophagy 2026 Mar;22(3):468-483

Non-canonical role of "S6K1-SGK1" pathway in neuronal necroptosis following traumatic brain injury.

Wang S, Tan Y, Hu M, Wang M, Liang L, Luo X, Chen D, Jiang B, Chen C, Huang J, Xiong K
Genes & diseases 2026 Jul;13(4):101876

Integrated microbiota and metabolomic analysis demonstrates the growth-promoting effects of Lactobacillus plantarum in Nile tilapia (Oreochromis nilotica).

Li L, Wang Y, Li Y, Wang T, Wang Z, Zhou N, Qiao F, Du ZY, Zhang ML
Animal microbiome 2026 Jan 14;8(1):14

Fibrillarin-dependent 2'-O-methylation modulates RPS28 ribosome incorporation and oncogenic translation.

Groza P, Kumari K, Esteva-Socias M, Schott J, Bhattarai DP, Sajkowska JJ, Dasgupta R, Peula C, Destefanis E, Williams C, Marchand V, Wikström P, Wiberg R, Campos AB, Gilthorpe JD, Pop B, Mateus A, Motorin Y, Dassi E, Petzold K, Tuorto F, Aguilo F
Cancer letters 2026 Feb 28;639:218124

ANGPTL8 accelerates bone loss in diabetic mice by promoting osteoclastic differentiation and inhibiting osteoblastic differentiation through AMPK pathway-mediated metabolic reprogramming.

Tuo P, Mu W, Bai X, Wang S, Hu L, Xu Y, Mao R, Liu Y, Yuan Y, Zhang Q, Guo X, Ma S, Wang X
Cellular and molecular life sciences : CMLS 2026 Feb 23;83(1)

Ascites circRNA ASCOR Drives Platinum Resistance of High-Grade Serous Ovarian Cancer by Facilitating RPA1 Nuclear Translocation.

Liu H, Zhu C, Yao X, Liu Y, Zhu J, Li Y, Xu H, Peng C, Shan G, Chen L, Zhou Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr;13(23):e18922

Vitamin K(2) emerges as the key mediator: Cetobacterium somerae ZNN-1 increases muscle protein deposition and improves liver health in Nile tilapia (Oreochromis niloticus).

Zhou N, Liu J, Zhang X, Xiao G, Zhang M
Journal of animal science and biotechnology 2026 Apr 11;17(1)

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition.

Tian X, Liu D, Liu B, Lan Y, Zhou J
FEBS open bio 2025 Oct;15(10):1658-1666

miR-199a functions downstream of MeCP2 in neurons of MECP2 duplication syndrome models.

Akaba Y, Takahashi S, Adachi S, Nishimura M, Suzuki K, Nakashima H, Nakashima K, Kira R, Chong PF, Sakai Y, Hayashi Y, Kushima I, Mori D, Arioka Y, Okumura H, Nakayama A, Mizuno S, Yamamoto T, Osakada F, Ozaki N, Tsujimura K
iScience 2025 Nov 21;28(11):113789

UFMylation safeguards human hepatocyte differentiation and liver homeostasis by regulating ribosome dissociation.

Yang S, Wang L, Gao R, Li Y, Zhang D, Wang C, Liu G, Na J, Xu P, Wang X, Jia Y, Huang Y
Cell reports 2025 May 27;44(5):115686

LINC02154 Promotes Esophageal Squamous Cell Carcinoma Progression via the PI3K-AKT-mTOR Signaling Pathway by Interacting With IGF2BP2.

Zhang M, Zhang C, Zhou F, Yang R, Feng Y, Ji Y, Ren H, Ming L
Molecular carcinogenesis 2025 Jun;64(6):985-996

Porcine reproductive and respiratory syndrome virus nsp2-related proteins induce host translational arrest by specifically impairing the mTOR signaling cascade.

Jiao X, Chen X, Li Q, Li C, Li Y
Veterinary microbiology 2025 Jul;306:110562

Anti-sarcopenic effects of active vitamin D through modulation of anabolic and catabolic signaling pathways in human skeletal muscle: A randomized controlled trial.

Kawahara T, Inazu T, Mizuno S, Tominaga N, Toda M, Toyama N, Kawahara C, Suzuki G, DPVD Research Group
Metabolism: clinical and experimental 2025 Jul;168:156240

DDX3 Regulates the Cap-Independent Translation of the Japanese Encephalitis Virus via Its Interactions with PABP1 and the Untranslated Regions of the Viral Genome.

Li C, Zhang L, Tang C, Chen X, Shi J, Li Q, Jiao X, Guo J, Wang B, Bu K, Wahaab A, Yuan Y, Sun MA, Li Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jul;12(27):e2502493

RIOK3 mediates the degradation of 40S ribosomes.

Huang Z, Diehl FF, Wang M, Li Y, Song A, Chen FX, Rosa-Mercado NA, Beckmann R, Green R, Cheng J
Molecular cell 2025 Feb 20;85(4):802-814.e12

ASS1 facilitates T-ALL progression via the arginine-mediated mTORC1/c-Myc signaling pathway.

Zhang Z, Liu X, Wu Q, Liang J, Zhao Y, Deng J, Wang Y, Yu Q, Ye Z, Zhu H, Lin J
Scientific reports 2025 Dec 15;15(1):43783

The tRNA Gm18 methyltransferase TARBP1 promotes hepatocellular carcinoma progression via metabolic reprogramming of glutamine.

Shi X, Zhang Y, Wang Y, Wang J, Gao Y, Wang R, Wang L, Xiong M, Cao Y, Ou N, Liu Q, Ma H, Cai J, Chen H
Cell death and differentiation 2024 Sep;31(9):1219-1234

mTOR/miR-142-3p/PRAS40 signaling cascade is critical for tuberous sclerosis complex-associated renal cystogenesis.

Zhao S, Hao S, Zhou J, Chen X, Zhang T, Qi Z, Zhang T, Jalal S, Zhai C, Yin L, Bo Y, Teng H, Wang Y, Gao D, Zhang H, Huang L
Cellular & molecular biology letters 2024 Sep 27;29(1):125

The Role of Heat-Induced Stress Granules in the Blood-Testis Barrier of Mice.

Zhao Z, Cai Y, Lin X, Liu N, Qin Y, Wu Y
International journal of molecular sciences 2024 Mar 25;25(7)

Phosphocholine inhibits proliferation and reduces stemness of endometrial cancer cells by downregulating mTOR-c-Myc signaling.

Gong K, Zheng Y, Liu Y, Zhang T, Song Y, Chen W, Guo L, Zhou J, Liu W, Fang T, Chen Y, Wang J, Pan F, Shi K
Cellular and molecular life sciences : CMLS 2024 Dec 16;82(1):3

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Hong Y, Zhou X, Li Q, Chen J, Wei Y, Shen L, Long C, Wu S, Wei G
Toxicology in vitro : an international journal published in association with BIBRA 2023 Sep;91:105626

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Wolczyk M, Serwa R, Kominek A, Klejman A, Milek J, Chwałek M, Turos-Korgul L, Charzyńska A, Dabrowski M, Dziembowska M, Skorski T, Piwocka K, Podszywalow-Bartnicka P
iScience 2023 Apr 21;26(4):106543

Branched-chain amino acid catabolism breaks glutamine addiction to sustain hepatocellular carcinoma progression.

Yang D, Liu H, Cai Y, Lu K, Zhong X, Xing S, Song W, Zhang Y, Ye L, Zhu X, Wang T, Zhang P, Li ST, Feng J, Jia W, Zhang H, Gao P
Cell reports 2022 Nov 22;41(8):111691

Overexpressed p-S6 associates with lymph node metastasis and predicts poor prognosis in non-small cell lung cancer.

Tang Y, Luo J, Zhou Y, Zang H, Yang Y, Liu S, Zheng H, Ma J, Fan S, Wen Q
BMC cancer 2022 May 20;22(1):564

YB1 associates with oncogenetic roles and poor prognosis in nasopharyngeal carcinoma.

Zhan Y, Chen X, Zheng H, Luo J, Yang Y, Ning Y, Wang H, Zhang Y, Zhou M, Wang W, Fan S
Scientific reports 2022 Mar 8;12(1):3699

Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1.

Zhao K, Ke Z, Hu H, Liu Y, Li A, Hua R, Guo F, Xiao J, Zhang Y, Duan L, Yan XF, Gao YG, Liu B, Xia Y, Li Y
Microbiology spectrum 2021 Sep 3;9(1):e0016921

Ribosomal proteins as distinct "passengers" of microvesicles: new semantics in myeloma and mesenchymal stem cells' communication.

Dabbah M, Lishner M, Jarchowsky-Dolberg O, Tartakover-Matalon S, Brin YS, Pasmanik-Chor M, Neumann A, Drucker L
Translational research : the journal of laboratory and clinical medicine 2021 Oct;236:117-132

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Fu Y, Wei Y, Zhou Y, Wu H, Hong Y, Long C, Wang J, Wu Y, Wu S, Shen L, Wei G
Endocrinology 2021 Oct 1;162(10)

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Hong Y, Zhou Y, Shen L, Wei Y, Long C, Fu Y, Wu H, Wang J, Wu Y, Wu S, Wei G
Ecotoxicology and environmental safety 2021 Dec 20;227:112889

A post-transcriptional program of chemoresistance by AU-rich elements and TTP in quiescent leukemic cells.

Lee S, Micalizzi D, Truesdell SS, Bukhari SIA, Boukhali M, Lombardi-Story J, Kato Y, Choo MK, Dey-Guha I, Ji F, Nicholson BT, Myers DT, Lee D, Mazzola MA, Raheja R, Langenbucher A, Haradhvala NJ, Lawrence MS, Gandhi R, Tiedje C, Diaz-Muñoz MD, Sweetser DA, Sadreyev R, Sykes D, Haas W, Haber DA, Maheswaran S, Vasudevan S
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