338915

antibody from BioLegend
Targeting: KDR CD309, FLK1, VEGFR, VEGFR2
Provider product page for 338915

Antibody data

Product number
338915 - Provider product page
Provider
BioLegend
Product name
PerCP/Cy5.5 anti-human CD309 (VEGFR2, Flk-1)
Antibody type
Monoclonal
Antigen
CD309 (VEGFR2)
Description
VEGF-R2, known as KDR, CD309, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and autophosphorylation, stimulating endothelial cell proliferation and migration.
Reactivity
Human
Host
Mouse
Conjugate
Far-Red dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
KDR protein structure - 338915 shown in red.