Ab132016

antibody from Aladdin Scientific Corporation

Targeting: CRTC2 TORC2

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

Ab132016

Provider

Aladdin Scientific Corporation

Product name

Recombinant TORC2 Antibody

Antibody type

Recombinant

Description

Rabbit anti Human TORC2 Antibody, Recombinant (R08-5F2), could be used for WB, IHC and so on.Application:WB: 1/500-1/2000IHC: 1/50-1/100Protein FunctionTranscriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

AA 680-693


Antibody clone number

R08-5F2

Vial size

100μl,10μl,1ml,50μl

Concentration

0,7 mg/ml

Storage

Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.