Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- Ab132016 - Provider product page
- Provider
- Aladdin Scientific
- Product name
- Recombinant TORC2 Antibody
- Antibody type
- Recombinant
- Description
- Rabbit anti Human TORC2 Antibody, Recombinant (R08-5F2), could be used for WB, IHC and so on.Application:WB: 1/500-1/2000IHC: 1/50-1/100Protein FunctionTranscriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Antigen sequence
AA 680-693
- Antibody clone number
- R08-5F2
- Vial size
- 100μl,10μl,1ml,50μl
- Concentration
- 0,7 mg/ml
- Storage
- Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
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Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Recombinant TORC2 Antibody (Ab132016) - Western Blot All lanes: Recombinant TORC2 Antibody (Ab132016) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution Predicted band size: 73 kDa Observed band size: 81 kDa Exposure time: 13.3 s
Supportive validation
- Submitted by
- Aladdin Scientific (provider)
- Main image
- Experimental details
- Recombinant TORC2 Antibody (Ab132016) - IHC Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant TORC2 Antibody (Ab132016). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.