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Learn14220-1-AP
antibody from Proteintech Group
Targeting: NFKB1
KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [173]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 14220-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14220-1-AP, RRID:AB_2153393
- Product name
- NFKB1 antibody
- Antibody type
- Polyclonal
- Description
- NFKB1 antibody (Cat. #14220-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Poly-(ADP-ribose) polymerases inhibition by olaparib attenuates activities of the NLRP3 inflammasome and of NF-κB in THP-1 monocytes.
IL-32/NFκB/miR-205 loop sustains the high expression of IL-32 and enhances the motility of cervical cancer cells.
Pirfenidone alleviates fibrosis by acting on tumour-stroma interplay in pancreatic cancer.
Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer.
Acupuncture alleviates CUMS-induced depression-like behaviors of rats by regulating oxidative stress, neuroinflammation and ferroptosis.
IRAK1 deficiency potentiates the efficacy of radiotherapy in repressing cervical cancer development.
Microglial Ffar4 deficiency promotes cognitive impairment in the context of metabolic syndrome.
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Feline umbilical cord-derived mesenchymal stem cells: isolation, identification, and antioxidative stress role through NF-κB signaling pathway.
Role of NLRP3 inflammasome activation in HCC cell progression.
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Paeoniflorin alleviates inflammation in bovine mammary epithelial cells induced by Staphylococcus haemolyticus through TLR2/NF-κB signaling pathways.
Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage.
Ergosterol Isolated from Antrodia camphorata Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice.
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Transcriptome Profiling of Vero E6 Cells during Original Parental or Cell-Attenuated Porcine Epidemic Diarrhea Virus Infection.
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.
Halofuginone ameliorates systemic lupus erythematosus by targeting Blk in myeloid-derived suppressor cells.
SPON2 promotes the bone metastasis of lung adenocarcinoma via activation of the NF-κB signaling pathway.
Endogenous hydrogen sulfide inhibition suppresses tumor growth by promoting apoptosis and pyroptosis in esophageal cancer cells.
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein.
LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis.
Galectin-3 Inhibition Ameliorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice.
Hyperthermia promotes exosome secretion by regulating Rab7b while increasing drug sensitivity in adriamycin-resistant breast cancer.
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Antihepatofibrotic effect of Guizhifuling pill on carbon tetrachloride-induced liver fibrosis in mice.
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
MicroRNA-124 modulates neuroinflammation in acute methanol poisoning rats via targeting Krüppel-like factor-6.
Pseudorabies Virus ICP0 Abolishes Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Degrading P65.
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Smilax china L. flavonoid alleviates HFHS-induced inflammation by regulating the gut-liver axis in mice.
Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation.
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.
Hepatic interferon regulatory factor 8 expression suppresses hepatocellular carcinoma progression and enhances the response to anti-programmed cell death protein-1 therapy.
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Circular RNA circNFKB1 promotes osteoarthritis progression through interacting with ENO1 and sustaining NF-κB signaling.
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Midkine promotes breast cancer cell proliferation and migration by upregulating NR3C1 expression and activating the NF-κB pathway.
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
RBM23 Drives Hepatocellular Carcinoma by Activating NF-κB Signaling Pathway.
Remote Limb Ischemic Postconditioning Protects against Ischemic Stroke via Modulating Microglia/Macrophage Polarization in Mice.
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia.
HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.
SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Prussian blue nanozyme-mediated nanoscavenger ameliorates acute pancreatitis via inhibiting TLRs/NF-κB signaling pathway.
Dimethyl itaconate inhibits LPS‑induced microglia inflammation and inflammasome‑mediated pyroptosis via inducing autophagy and regulating the Nrf‑2/HO‑1 signaling pathway.
Dipeptidyl peptidase-4 (DPP4) inhibitor sitagliptin alleviates liver inflammation of diabetic mice by acting as a ROS scavenger and inhibiting the NFκB pathway.
Tetrahydropalmatine Regulates BDNF through TrkB/CAM Interaction to Alleviate the Neurotoxicity Induced by Methamphetamine.
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Resveratrol sustains intestinal barrier integrity, improves antioxidant capacity, and alleviates inflammation in the jejunum of ducks exposed to acute heat stress.
Paeoniflorin inhibited nod-like receptor protein-3 inflammasome and NF-κB-mediated inflammatory reactions in diabetic foot ulcer by inhibiting the chemokine receptor CXCR2.
Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
Hsa_circ_0056558 regulates cyclin-dependent kinase 6 by sponging microRNA-1290 to suppress the proliferation and differentiation in ankylosing spondylitis.
Fish Hydrolysate Supplementation Containing n-3 Long Chain Polyunsaturated Fatty Acids and Peptides Prevents LPS-Induced Neuroinflammation.
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Combination of Geniposide and Eleutheroside B Exerts Antidepressant-like Effect on Lipopolysaccharide-Induced Depression Mice Model.
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
The promotion of tetrabromobisphenol A exposure on Ishikawa cells proliferation and pivotal role of ubiquitin-mediated IκB' degradation.
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Extracellular vesicles secreted from mesenchymal stem cells exert anti-apoptotic and anti-inflammatory effects via transmitting microRNA-18b in rats with diabetic retinopathy.
Resveratrol ameliorates sevoflurane-induced cognitive impairment by activating the SIRT1/NF-κB pathway in neonatal mice.
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Bta-miR-223 Targeting CBLB Contributes to Resistance to Staphylococcus aureus Mastitis Through the PI3K/AKT/NF-κB Pathway.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Antiprolactinoma Effect of Hordenine by Inhibiting MAPK Signaling Pathway Activation in Rats.
Antidepressant-Like Effect of Geniposide in Mice Exposed to a Chronic Mild Stress Involves the microRNA-298-5p-Mediated Nox1.
Herpes Simplex Virus 1 UL2 Inhibits the TNF-α-Mediated NF-κB Activity by Interacting With p65/p50.
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Carvacrol may alleviate vascular inflammation in diabetic db/db mice.
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
A multifunctional anti-inflammatory drug that can specifically target activated macrophages, massively deplete intracellular H(2)O(2), and produce large amounts CO for a highly efficient treatment of osteoarthritis.
Chlorogenic acid inhibits the proliferation of human lung cancer A549 cell lines by targeting annexin A2 in vitro and in vivo.
CiRS-7 functions as a ceRNA of RAF-1/PIK3CD to promote metastatic progression of oral squamous cell carcinoma via MAPK/AKT signaling pathways.
Pterostilbene Ameliorates Glycemic Control, Dyslipidemia and Liver Injury in Type 2 Diabetes Rats.
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein.
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Blockade of periostin-dependent migration and adhesion by curcumol via inhibition of nuclear factor kappa B signaling in hepatic stellate cells.
LncRNA RP11-86H7.1 promotes airway inflammation induced by TRAPM2.5 by acting as a ceRNA of miRNA-9-5p to regulate NFKB1 in HBECS.
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway.
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.
Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.
Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation.
NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress.
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Down-regulation of taurine-up-regulated gene 1 attenuates inflammation by sponging miR-9-5p via targeting NF-κB1/p50 in multiple sclerosis.
Adipose-derived mesenchymal stem cells ameliorate acute liver injury in rat model of CLP induced-sepsis via sTNFR1.
Polydatin alleviates traumatic spinal cord injury by reducing microglial inflammation via regulation of iNOS and NLRP3 inflammasome pathway.
Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model.
Neuroprotective Effects of Ginsenosides against Cerebral Ischemia.
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.
Effect of dexmedetomidine on kidney injury in sepsis rats through TLR4/MyD88/NF-κB/iNOS signaling pathway.
Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis.
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Genistein inhibits Ang II-induced CRP and MMP-9 generations via the ER-p38/ERK1/2-PPARγ-NF-κB signaling pathway in rat vascular smooth muscle cells.
Paeonol-mediated apoptosis of hepatocellular carcinoma cells by NF-κB pathway.
Protective effect of metformin on a rat model of lipopolysaccharide-induced preeclampsia.
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Investigation of the variants at the binding site of inflammatory transcription factor NF-κB in patients with end-stage renal disease.
SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.
Pretreatment with Lactobacillus reuteri F-9-35 attenuates ethanol-induced gastric injury in rats.
Alpha-Lipoic Acid Preconditioning and Ischaemic Postconditioning Synergistically Protect Rats from Cerebral Injury Induced by Ischemia and Reperfusion Partly via Inhibition TLR4/MyD88/ NF-κB Signaling Pathway.
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-κB Signaling Pathway.
Serum and Ectopic Endometrium from Women with Endometriosis Modulate Macrophage M1/M2 Polarization via the Smad2/Smad3 Pathway.
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury.
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death.
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis.
Neurotoxicity, behavioral changes and gene-expression profile of mice exposed to SnS(2) nanoflowers.
TLR4 signaling pathway mediates the LPS/ischemia-induced expression of monocytechemotactic protein-induced protein 1 in microglia.
Arsenic and/or copper caused inflammatory response via activation of inducible nitric oxide synthase pathway and triggered heat shock protein responses in testis tissues of chicken.
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Knockdown of SNHG15 suppresses renal cell carcinoma proliferation and EMT by regulating the NF-κB signaling pathway.
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-κB signaling pathway in vivo and in vitro.
Propofol protects against endotoxin-induced myocardial injury by inhibiting NF-κB-mediated inflammation.
Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress.
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway.
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide.
Effect of TLR4/MyD88 signaling pathway on sepsis-associated acute respiratory distress syndrome in rats, via regulation of macrophage activation and inflammatory response.
Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Acinar Cell Injury via MicroRNA-30a-5p-Mediated Inhibition of High-Temperature Requirement A/Transforming Growth Factor Beta 1 Inflammatory Signaling.
RNA-sequencing dissects the transcriptome of polyploid cancer cells that are resistant to combined treatments of cisplatin with paclitaxel and docetaxel.
Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex.
miR-15b-5p resensitizes colon cancer cells to 5-fluorouracil by promoting apoptosis via the NF-κB/XIAP axis.
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells.
Deoxyelephantopin induces apoptosis in HepG2 cells via oxidative stress, NF-κB inhibition and mitochondrial dysfunction.
High-mobility group box 1 is overexpressed in cervical carcinoma and promotes cell invasion and migration in vitro.
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
Herpes Simplex Virus 1 UL24 Abrogates the DNA Sensing Signal Pathway by Inhibiting NF-κB Activation.
Hepatoprotective Effect of Quercetin on Endoplasmic Reticulum Stress and Inflammation after Intense Exercise in Mice through Phosphoinositide 3-Kinase and Nuclear Factor-Kappa B.
Carnosic acid alleviates chronic alcoholic liver injury by regulating the SIRT1/ChREBP and SIRT1/p66shc pathways in rats.
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease.
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Herpes simplex virus 1 E3 ubiquitin ligase ICP0 protein inhibits tumor necrosis factor alpha-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Mustafa K, Han Y, He D, Wang Y, Niu N, Jose PA, Jiang Y, Kopp JB, Lee H, Qu P
PloS one 2024;19(2):e0295837
PloS one 2024;19(2):e0295837
IL-32/NFκB/miR-205 loop sustains the high expression of IL-32 and enhances the motility of cervical cancer cells.
Liu J, Yang K, Lin X, Xu J, Cui X, Hao J, Wang W, Wang W, Li L, Hao M
Human cell 2024 Sep;37(5):1434-1445
Human cell 2024 Sep;37(5):1434-1445
Pirfenidone alleviates fibrosis by acting on tumour-stroma interplay in pancreatic cancer.
Lei Y, Xu J, Xiao M, Wu D, Xu H, Yang J, Mao X, Pan H, Yu X, Shi S
British journal of cancer 2024 May;130(9):1505-1516
British journal of cancer 2024 May;130(9):1505-1516
Deubiquitinase USP4 suppresses antitumor immunity by inhibiting IRF3 activation and tumor cell-intrinsic interferon response in colorectal cancer.
Zhou Y, Li H, Zhang Y, Zhao E, Huang C, Pan X, Shu F, Liu Z, Tang N, Li F, Liao W
Cancer letters 2024 May 1;589:216836
Cancer letters 2024 May 1;589:216836
Acupuncture alleviates CUMS-induced depression-like behaviors of rats by regulating oxidative stress, neuroinflammation and ferroptosis.
Shen J, Hao C, Yuan S, Chen W, Tong T, Chen Y, Shahzad Aslam M, Yan S, Li J, Zeng J, Liu S, Chen Y, Jiang Y, Li P, Meng X
Brain research 2024 Mar 1;1826:148715
Brain research 2024 Mar 1;1826:148715
IRAK1 deficiency potentiates the efficacy of radiotherapy in repressing cervical cancer development.
Chen W, Xie X, Liu C, Liao J, Wei Y, Wu R, Hong J
Cellular signalling 2024 Jul;119:111192
Cellular signalling 2024 Jul;119:111192
Microglial Ffar4 deficiency promotes cognitive impairment in the context of metabolic syndrome.
Wang W, Li J, Cui S, Li J, Ye X, Wang Z, Zhang T, Jiang X, Kong Y, Chen X, Chen YQ, Zhu S
Science advances 2024 Feb 2;10(5):eadj7813
Science advances 2024 Feb 2;10(5):eadj7813
Bta-miR-149-3p suppresses inflammatory response in bovine Sertoli cells exposed to microcystin-leucine arginine (MC-LR) through TLR4/NF-kB signaling pathway.
Xue W, Tianrun W, Jiaqi Y, Xin L, Ruxue D, Peng Z
Ecotoxicology and environmental safety 2024 Aug;281:116636
Ecotoxicology and environmental safety 2024 Aug;281:116636
A novel 2-iminobenzimidazole compound, XYA1353, displays in vitro and in vivo anti-myeloma activity via targeting NF-κB signaling.
Gao J, Zhou J, Zhang M, Zhang Y, Zeng Y, Li S, Xu K, Yao R
Molecular and cellular biochemistry 2024 Apr;479(4):843-857
Molecular and cellular biochemistry 2024 Apr;479(4):843-857
Feline umbilical cord-derived mesenchymal stem cells: isolation, identification, and antioxidative stress role through NF-κB signaling pathway.
Zhai ZH, Li J, You Z, Cai Y, Yang J, An J, Zhao DP, Wang HJ, Dou MM, Du R, Qin J
Frontiers in veterinary science 2023;10:1203012
Frontiers in veterinary science 2023;10:1203012
Role of NLRP3 inflammasome activation in HCC cell progression.
Dai B, Cao H, Hu Y, Gong Z, Huang X, Chen Y, Liu F, Peng X, Zhang Y, Lei X
Heliyon 2023 Sep;9(9):e19542
Heliyon 2023 Sep;9(9):e19542
NKRF in Cardiac Fibroblasts Protects against Cardiac Remodeling Post-Myocardial Infarction via Human Antigen R.
Guo C, Ji W, Yang W, Deng Q, Zheng T, Wang Z, Sui W, Zhai C, Yu F, Xi B, Yu X, Xu F, Zhang Q, Zhang W, Kong J, Zhang M, Zhang C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Oct;10(30):e2303283
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Novel c-Myc G4 stabilizer EP12 promotes myeloma cytotoxicity by disturbing NF-κB signaling.
Yao R, Zhang Y, Zeng Y, Zhang Y, Liu L, Gao J
Experimental cell research 2023 Oct 1;431(1):113759
Experimental cell research 2023 Oct 1;431(1):113759
Transcription factor Dmrt1 triggers the SPRY1-NF-κB pathway to maintain testicular immune homeostasis and male fertility.
Zhang MF, Wan SC, Chen WB, Yang DH, Liu WQ, Li BL, Aierken A, Du XM, Li YX, Wu WP, Yang XC, Wei YD, Li N, Peng S, Li XL, Li GP, Hua JL
Zoological research 2023 May 18;44(3):505-521
Zoological research 2023 May 18;44(3):505-521
Paeoniflorin alleviates inflammation in bovine mammary epithelial cells induced by Staphylococcus haemolyticus through TLR2/NF-κB signaling pathways.
Shen J, Yang F, Wang G, Mou X, Li J, Ding X, Wang X, Li H
Research in veterinary science 2023 Mar;156:95-103
Research in veterinary science 2023 Mar;156:95-103
Activation of estrogen receptor α inhibits TLR4 signaling in macrophages and alleviates the instability of atherosclerotic plaques in the postmenopausal stage.
Meng Q, Bi Y, Feng H, Ding X, Zhang S, Chen Q, Wang L, Zhang Q, Li Y, Tong H, Wu L, Bian H
International immunopharmacology 2023 Mar;116:109825
International immunopharmacology 2023 Mar;116:109825
Ergosterol Isolated from Antrodia camphorata Suppresses LPS-Induced Neuroinflammatory Responses in Microglia Cells and ICR Mice.
Sun P, Li W, Guo J, Peng Q, Ye X, Hu S, Liu Y, Liu W, Chen H, Qiao J, Sun B
Molecules (Basel, Switzerland) 2023 Mar 6;28(5)
Molecules (Basel, Switzerland) 2023 Mar 6;28(5)
p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.
Zhu X, Huang B, Zhao F, Lian J, He L, Zhang Y, Ji L, Zhang J, Yan X, Zeng T, Ma C, Liang Y, Zhang C, Lin J
Nucleic acids research 2023 Mar 21;51(5):2195-2214
Nucleic acids research 2023 Mar 21;51(5):2195-2214
Transcriptome Profiling of Vero E6 Cells during Original Parental or Cell-Attenuated Porcine Epidemic Diarrhea Virus Infection.
Peng O, Wu Y, Hu F, Xia Y, Geng R, Huang Y, Zeng S, Hu G, Xue C, Zhang H, Cao Y
Viruses 2023 Jun 23;15(7)
Viruses 2023 Jun 23;15(7)
circACTA2 inhibits NLRP3 inflammasome-mediated inflammation via interacting with NF-κB in vascular smooth muscle cells.
Bai Y, Zhang L, Zheng B, Zhang X, Zhang H, Zhao A, Yu J, Yang Z, Wen J
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
Cellular and molecular life sciences : CMLS 2023 Jul 27;80(8):229
RNA-binding motif 4 promotes angiogenesis in HCC by selectively activating VEGF-A expression.
Han H, Lin T, Wang Z, Song J, Fang Z, Zhang J, You X, Du Y, Ye J, Zhou G
Pharmacological research 2023 Jan;187:106593
Pharmacological research 2023 Jan;187:106593
Halofuginone ameliorates systemic lupus erythematosus by targeting Blk in myeloid-derived suppressor cells.
Ni J, Li X, Tu X, Zhu H, Wang S, Hou Y, Dou H
International immunopharmacology 2023 Jan;114:109487
International immunopharmacology 2023 Jan;114:109487
SPON2 promotes the bone metastasis of lung adenocarcinoma via activation of the NF-κB signaling pathway.
Wu M, Kong D, Zhang Y
Bone 2023 Feb;167:116630
Bone 2023 Feb;167:116630
Endogenous hydrogen sulfide inhibition suppresses tumor growth by promoting apoptosis and pyroptosis in esophageal cancer cells.
Wang HG, Wang D, Sarfraz M, Afzal A, Jing MR, Zhang YX, Cai CB, Qi HW, Chen HJ, Li T, Hu SJ, Liu HX, Ji XY, Wu DD
Translational oncology 2023 Dec;38:101770
Translational oncology 2023 Dec;38:101770
Dietary pectin attenuates Salmonella typhimurium-induced colitis by modulating the TLR2-NF-κB pathway and intestinal microbiota in mice.
Li J, Bai J, Song Z, Ji Y, Chen Z, Yang Y, Wu Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Dec;182:114100
Dissecting T-cell heterogeneity in esophageal squamous cell carcinoma reveals the potential role of LAIR2 in antitumor immunity.
Wang P, Zhuang W, Zheng Z, Zhang L, Zhang X, Chen Q
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
Clinical and experimental immunology 2023 Dec 11;214(1):36-49
Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein.
Wang L, Yu X, Li H, He D, Zeng S, Xiang Z
Chinese medicine 2023 Dec 1;18(1):158
Chinese medicine 2023 Dec 1;18(1):158
LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis.
Sha L, Li J, Shen H, Wang Q, Meng P, Zhang X, Deng Y, Zhu W, Xu Q
Cell reports 2023 Aug 29;42(8):112975
Cell reports 2023 Aug 29;42(8):112975
Galectin-3 Inhibition Ameliorates Streptozotocin-Induced Diabetic Cardiomyopathy in Mice.
Zhu N, Zhu L, Huang B, Xiang W, Zhao X
Frontiers in cardiovascular medicine 2022;9:868372
Frontiers in cardiovascular medicine 2022;9:868372
Hyperthermia promotes exosome secretion by regulating Rab7b while increasing drug sensitivity in adriamycin-resistant breast cancer.
Xu D, Tang WJ, Zhu YZ, Liu Z, Yang K, Liang MX, Chen X, Wu Y, Tang JH, Zhang W
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):246-257
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2022;39(1):246-257
Expression Regulation of Water Reabsorption Genes and Transcription Factors in the Kidneys of Lepus yarkandensis.
Luo S, Li Y, Li S, Jiang R, Deng F, Liu G, Zhang J
Frontiers in physiology 2022;13:856427
Frontiers in physiology 2022;13:856427
Antihepatofibrotic effect of Guizhifuling pill on carbon tetrachloride-induced liver fibrosis in mice.
Baogui XU, Jiawen Z, Xiaoxiao T, Falei Y, Zhongliang L, Zuisu Y, Xianjun D
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):715-722
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2022 Oct;42(5):715-722
pH/ROS Dual-Sensitive Natural Polysaccharide Nanoparticles Enhance "One Stone Four Birds" Effect of Rhein on Ulcerative Colitis.
Qi S, Luo R, Han X, Nie W, Ye N, Fu C, Gao F
ACS applied materials & interfaces 2022 Nov 16;14(45):50692-50709
ACS applied materials & interfaces 2022 Nov 16;14(45):50692-50709
MicroRNA-124 modulates neuroinflammation in acute methanol poisoning rats via targeting Krüppel-like factor-6.
Zhou S, Li J, Zhang X, Xiong W
Bioengineered 2022 May;13(5):13507-13519
Bioengineered 2022 May;13(5):13507-13519
Pseudorabies Virus ICP0 Abolishes Tumor Necrosis Factor Alpha-Induced NF-κB Activation by Degrading P65.
Zhang X, Xie J, Gao M, Yan Z, Chen L, Wei S, Feng R
Viruses 2022 May 2;14(5)
Viruses 2022 May 2;14(5)
Scutellarein protects against cardiac hypertrophy via suppressing TRAF2/NF-κB signaling pathway.
Shi X, Hu Y, Jiang Y, Wu J, Zhang C, Zhang J, Wu S, Wu Y, Dong W, Li J
Molecular biology reports 2022 Mar;49(3):2085-2095
Molecular biology reports 2022 Mar;49(3):2085-2095
Methionine strengthens anti-inflammation of rice protein via depressing NF-κB activation and stimulating Msr expression in rats fed cholesterol-enriched diets.
Wang Z, Liang M, Liu B, Yang L
Food science and biotechnology 2022 Jun;31(6):745-758
Food science and biotechnology 2022 Jun;31(6):745-758
Smilax china L. flavonoid alleviates HFHS-induced inflammation by regulating the gut-liver axis in mice.
Li X, Chu L, Liu S, Zhang W, Lin L, Zheng G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153728
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jan;95:153728
Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation.
Ma Z, Liu Y, Li C, Zhang Y, Lin N
Chinese medicine 2022 Jan 4;17(1):2
Chinese medicine 2022 Jan 4;17(1):2
Hyaluronic Acid-Modified Nanoparticles Self-Assembled from Linoleic Acid-Conjugated Chitosan for the Codelivery of miR34a and Doxorubicin in Resistant Breast Cancer.
Yang X, Shang P, Ji J, Malichewe C, Yao Z, Liao J, Du D, Sun C, Wang L, Tang YJ, Guo X
Molecular pharmaceutics 2022 Jan 3;19(1):2-17
Molecular pharmaceutics 2022 Jan 3;19(1):2-17
Elevated expression of the rhythm gene NFIL3 promotes the progression of TNBC by activating NF-κB signaling through suppression of NFKBIA transcription.
Yang W, Li J, Zhang M, Yu H, Zhuang Y, Zhao L, Ren L, Gong J, Bi H, Zeng L, Xue Y, Yang J, Zhao Y, Wang S, Gao S, Fu Z, Li D, Zhang J, Wang T, Shan M, Tang B, Li X
Journal of experimental & clinical cancer research : CR 2022 Feb 18;41(1):67
Journal of experimental & clinical cancer research : CR 2022 Feb 18;41(1):67
Hepatic interferon regulatory factor 8 expression suppresses hepatocellular carcinoma progression and enhances the response to anti-programmed cell death protein-1 therapy.
Wu H, Li Y, Shi G, Du S, Wang X, Ye W, Zhang Z, Chu Y, Ma S, Wang D, Li Y, Chen Z, Birnbaumer L, Wang Z, Yang Y
Hepatology (Baltimore, Md.) 2022 Dec;76(6):1602-1616
Hepatology (Baltimore, Md.) 2022 Dec;76(6):1602-1616
L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats.
Wang Z, Liang M, Li H, Liu B, Yang L
Nutrition research and practice 2022 Dec;16(6):729-744
Nutrition research and practice 2022 Dec;16(6):729-744
The Integrated Analysis of Transcriptomics and Metabolomics Unveils the Therapeutical Effect of Asiatic Acid on Alcoholic Hepatitis in Rats.
Chen S, Huang Y, Su H, Zhu W, Wei Y, Long Y, Shi Y, Wei J
Inflammation 2022 Aug;45(4):1780-1799
Inflammation 2022 Aug;45(4):1780-1799
Circular RNA circNFKB1 promotes osteoarthritis progression through interacting with ENO1 and sustaining NF-κB signaling.
Tang S, Nie X, Ruan J, Cao Y, Kang J, Ding C
Cell death & disease 2022 Aug 9;13(8):695
Cell death & disease 2022 Aug 9;13(8):695
Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.
Wang Z, Liang M, Li H, Liu B, Yang L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2022 Aug 1;47(8):826-838
Midkine promotes breast cancer cell proliferation and migration by upregulating NR3C1 expression and activating the NF-κB pathway.
Zhang L, Song L, Xu Y, Xu Y, Zheng M, Zhang P, Wang Q
Molecular biology reports 2022 Apr;49(4):2953-2961
Molecular biology reports 2022 Apr;49(4):2953-2961
Tumor-promoting mechanisms of macrophage-derived extracellular vesicles-enclosed microRNA-660 in breast cancer progression.
Li C, Li R, Hu X, Zhou G, Jiang G
Breast cancer research and treatment 2022 Apr;192(2):353-368
Breast cancer research and treatment 2022 Apr;192(2):353-368
Celastrol Inhibits Canine Mammary Tumor Cells by Inducing Apoptosis via the Caspase Pathway.
Ou G, Jiang X, Gao A, Li X, Lin Z, Pei S
Frontiers in veterinary science 2021;8:801407
Frontiers in veterinary science 2021;8:801407
RBM23 Drives Hepatocellular Carcinoma by Activating NF-κB Signaling Pathway.
Han H, Lin T, Fang Z, Zhou G
BioMed research international 2021;2021:6697476
BioMed research international 2021;2021:6697476
Remote Limb Ischemic Postconditioning Protects against Ischemic Stroke via Modulating Microglia/Macrophage Polarization in Mice.
Han D, Wang J, Wen L, Sun M, Liu H, Gao Y
Journal of immunology research 2021;2021:6688053
Journal of immunology research 2021;2021:6688053
Metformin Corrects Glucose Metabolism Reprogramming and NLRP3 Inflammasome-Induced Pyroptosis via Inhibiting the TLR4/NF-κB/PFKFB3 Signaling in Trophoblasts: Implication for a Potential Therapy of Preeclampsia.
Zhang Y, Liu W, Zhong Y, Li Q, Wu M, Yang L, Liu X, Zou L
Oxidative medicine and cellular longevity 2021;2021:1806344
Oxidative medicine and cellular longevity 2021;2021:1806344
HIV-1 Vpr protein upregulates microRNA-210-5p expression to induce G2 arrest by targeting TGIF2.
Qiao J, Peng Q, Qian F, You Q, Feng L, Hu S, Liu W, Huang L, Shu X, Sun B
PloS one 2021;16(12):e0261971
PloS one 2021;16(12):e0261971
SARS-CoV-2 Nsp5 Activates NF-κB Pathway by Upregulating SUMOylation of MAVS.
Li W, Qiao J, You Q, Zong S, Peng Q, Liu Y, Hu S, Liu W, Li S, Shu X, Sun B
Frontiers in immunology 2021;12:750969
Frontiers in immunology 2021;12:750969
Morchella importuna Flavones Improve Intestinal Integrity in Dextran Sulfate Sodium-Challenged Mice.
Xu Y, Xie L, Tang J, He X, Zhang Z, Chen Y, Zhou J, Gan B, Peng W
Frontiers in microbiology 2021;12:742033
Frontiers in microbiology 2021;12:742033
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
Prussian blue nanozyme-mediated nanoscavenger ameliorates acute pancreatitis via inhibiting TLRs/NF-κB signaling pathway.
Xie X, Zhao J, Gao W, Chen J, Hu B, Cai X, Zheng Y
Theranostics 2021;11(7):3213-3228
Theranostics 2021;11(7):3213-3228
Dimethyl itaconate inhibits LPS‑induced microglia inflammation and inflammasome‑mediated pyroptosis via inducing autophagy and regulating the Nrf‑2/HO‑1 signaling pathway.
Yang S, Zhang X, Zhang H, Lin X, Chen X, Zhang Y, Lin X, Huang L, Zhuge Q
Molecular medicine reports 2021 Sep;24(3)
Molecular medicine reports 2021 Sep;24(3)
Dipeptidyl peptidase-4 (DPP4) inhibitor sitagliptin alleviates liver inflammation of diabetic mice by acting as a ROS scavenger and inhibiting the NFκB pathway.
Wang X, Ke J, Zhu YJ, Cao B, Yin RL, Wang Y, Wei LL, Zhang LJ, Yang LY, Zhao D
Cell death discovery 2021 Sep 7;7(1):236
Cell death discovery 2021 Sep 7;7(1):236
Tetrahydropalmatine Regulates BDNF through TrkB/CAM Interaction to Alleviate the Neurotoxicity Induced by Methamphetamine.
Liu L, Liu M, Zhao W, Zhao YL, Wang Y
ACS chemical neuroscience 2021 Sep 15;12(18):3373-3386
ACS chemical neuroscience 2021 Sep 15;12(18):3373-3386
Imbalanced inflammatory response in subchronic arsenic-induced liver injury and the protective effects of Ginkgo biloba extract in rats: Potential role of cytokines mediated cell-cell interactions.
Dong L, Liu Y, Wang D, Zhu K, Zou Z, Zhang A
Environmental toxicology 2021 Oct;36(10):2073-2092
Environmental toxicology 2021 Oct;36(10):2073-2092
Resveratrol sustains intestinal barrier integrity, improves antioxidant capacity, and alleviates inflammation in the jejunum of ducks exposed to acute heat stress.
Yang C, Luo P, Chen SJ, Deng ZC, Fu XL, Xu DN, Tian YB, Huang YM, Liu WJ
Poultry science 2021 Nov;100(11):101459
Poultry science 2021 Nov;100(11):101459
Paeoniflorin inhibited nod-like receptor protein-3 inflammasome and NF-κB-mediated inflammatory reactions in diabetic foot ulcer by inhibiting the chemokine receptor CXCR2.
Sun X, Wang X, Zhao Z, Chen J, Li C, Zhao G
Drug development research 2021 May;82(3):404-411
Drug development research 2021 May;82(3):404-411
Proof-of-concept study investigating the role of S100P-RAGE in nasopharyngeal carcinoma.
Wang C, Wang X, Han A, Wang Y, Jiang H
Experimental and therapeutic medicine 2021 May;21(5):470
Experimental and therapeutic medicine 2021 May;21(5):470
Hsa_circ_0056558 regulates cyclin-dependent kinase 6 by sponging microRNA-1290 to suppress the proliferation and differentiation in ankylosing spondylitis.
Li X, Zhou W, Li Z, Guan F
Autoimmunity 2021 Mar;54(2):114-128
Autoimmunity 2021 Mar;54(2):114-128
Fish Hydrolysate Supplementation Containing n-3 Long Chain Polyunsaturated Fatty Acids and Peptides Prevents LPS-Induced Neuroinflammation.
Chataigner M, Martin M, Lucas C, Pallet V, Layé S, Mehaignerie A, Bouvret E, Dinel AL, Joffre C
Nutrients 2021 Mar 2;13(3)
Nutrients 2021 Mar 2;13(3)
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
Xu G, Deng F, Zuo Q, Liu L, Dou K, Cheng Z, Cao W, Luo C, Yu C, Liu S, Zhu Y
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
Exosomal SNHG16 secreted by CSCs promotes glioma development via TLR7.
Zhang R, Li P, Lv H, Li N, Ren S, Xu W
Stem cell research & therapy 2021 Jun 16;12(1):349
Stem cell research & therapy 2021 Jun 16;12(1):349
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Cao W, Guo Y, Cheng Z, Xu G, Zuo Q, Nie L, Huang Y, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Combination of Geniposide and Eleutheroside B Exerts Antidepressant-like Effect on Lipopolysaccharide-Induced Depression Mice Model.
Zhang B, Chang HS, Hu KL, Yu X, Li LN, Xu XQ
Chinese journal of integrative medicine 2021 Jul;27(7):534-541
Chinese journal of integrative medicine 2021 Jul;27(7):534-541
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Zuo Q, Cheng Z, Zhang G, Xia Y, Xu G, Cao W, Yang X, Fu Y, He R, Fang P, Guo Y, Nie L, Huang Y, Liu L, Zhan J, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
The promotion of tetrabromobisphenol A exposure on Ishikawa cells proliferation and pivotal role of ubiquitin-mediated IκB' degradation.
Guan G, Su H, Wei X, Zheng Y, Jin X
Ecotoxicology and environmental safety 2021 Jan 1;207:111254
Ecotoxicology and environmental safety 2021 Jan 1;207:111254
Downregulating lncRNA PRNCR1 ameliorates LPS-induced pulmonary vascular endothelial cell injury by modulating miR-330-5p/TLR4 axis.
Yu Y, Sun H, Zhu L, Ji L, Liu H
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Journal of biochemical and molecular toxicology 2021 Feb;35(2):e22644
Extracellular vesicles secreted from mesenchymal stem cells exert anti-apoptotic and anti-inflammatory effects via transmitting microRNA-18b in rats with diabetic retinopathy.
Xu Z, Tian N, Li S, Li K, Guo H, Zhang H, Jin H, An M, Yu X
International immunopharmacology 2021 Dec;101(Pt B):108234
International immunopharmacology 2021 Dec;101(Pt B):108234
Resveratrol ameliorates sevoflurane-induced cognitive impairment by activating the SIRT1/NF-κB pathway in neonatal mice.
Tang XL, Wang X, Fang G, Zhao YL, Yan J, Zhou Z, Sun R, Luo AL, Li SY
The Journal of nutritional biochemistry 2021 Apr;90:108579
The Journal of nutritional biochemistry 2021 Apr;90:108579
African Swine Fever Virus MGF360-12L Inhibits Type I Interferon Production by Blocking the Interaction of Importin α and NF-κB Signaling Pathway.
Zhuo Y, Guo Z, Ba T, Zhang C, He L, Zeng C, Dai H
Virologica Sinica 2021 Apr;36(2):176-186
Virologica Sinica 2021 Apr;36(2):176-186
Bta-miR-223 Targeting CBLB Contributes to Resistance to Staphylococcus aureus Mastitis Through the PI3K/AKT/NF-κB Pathway.
Han S, Li X, Liu J, Zou Z, Luo L, Wu R, Zhao Z, Wang C, Shen B
Frontiers in veterinary science 2020;7:529
Frontiers in veterinary science 2020;7:529
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
Protective Effects of Cinnamaldehyde against Mesenteric Ischemia-Reperfusion-Induced Lung and Liver Injuries in Rats.
Almoiliqy M, Wen J, Qaed E, Sun Y, Lian M, Mousa H, Al-Azab M, Zaky MY, Chen D, Wang L, Al-Sharabi A, Liu Z, Sun P, Lin Y
Oxidative medicine and cellular longevity 2020;2020:4196548
Oxidative medicine and cellular longevity 2020;2020:4196548
Antiprolactinoma Effect of Hordenine by Inhibiting MAPK Signaling Pathway Activation in Rats.
Wang X, Guo RZ, Ma L, Ding QY, Meng JH, Chen YG, Wu JH
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3107290
Evidence-based complementary and alternative medicine : eCAM 2020;2020:3107290
Antidepressant-Like Effect of Geniposide in Mice Exposed to a Chronic Mild Stress Involves the microRNA-298-5p-Mediated Nox1.
Zou T, Zhang J, Liu Y, Zhang Y, Sugimoto K, Mei C
Frontiers in molecular neuroscience 2020;13:131
Frontiers in molecular neuroscience 2020;13:131
Herpes Simplex Virus 1 UL2 Inhibits the TNF-α-Mediated NF-κB Activity by Interacting With p65/p50.
Cai M, Liao Z, Zou X, Xu Z, Wang Y, Li T, Li Y, Ou X, Deng Y, Guo Y, Peng T, Li M
Frontiers in immunology 2020;11:549
Frontiers in immunology 2020;11:549
Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus.
Lv W, Graves DT, He L, Shi Y, Deng X, Zhao Y, Dong X, Ren Y, Liu X, Xiao E, Zhang Y
Theranostics 2020;10(14):6500-6516
Theranostics 2020;10(14):6500-6516
Carvacrol may alleviate vascular inflammation in diabetic db/db mice.
Zhao W, Deng C, Han Q, Xu H, Chen Y
International journal of molecular medicine 2020 Sep;46(3):977-988
International journal of molecular medicine 2020 Sep;46(3):977-988
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Almoiliqy M, Wen J, Xu B, Sun YC, Lian MQ, Li YL, Qaed E, Al-Azab M, Chen DP, Shopit A, Wang L, Sun PY, Lin Y
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
A multifunctional anti-inflammatory drug that can specifically target activated macrophages, massively deplete intracellular H(2)O(2), and produce large amounts CO for a highly efficient treatment of osteoarthritis.
Yang G, Fan M, Zhu J, Ling C, Wu L, Zhang X, Zhang M, Li J, Yao Q, Gu Z, Cai X
Biomaterials 2020 Oct;255:120155
Biomaterials 2020 Oct;255:120155
Chlorogenic acid inhibits the proliferation of human lung cancer A549 cell lines by targeting annexin A2 in vitro and in vivo.
Wang L, Du H, Chen P
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110673
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Nov;131:110673
CiRS-7 functions as a ceRNA of RAF-1/PIK3CD to promote metastatic progression of oral squamous cell carcinoma via MAPK/AKT signaling pathways.
Dou Z, Gao L, Ren W, Zhang H, Wang X, Li S, Zheng J, Kong X, Chi P, Zhi K
Experimental cell research 2020 Nov 15;396(2):112290
Experimental cell research 2020 Nov 15;396(2):112290
Pterostilbene Ameliorates Glycemic Control, Dyslipidemia and Liver Injury in Type 2 Diabetes Rats.
Zhang YJ, Sun HL, Wang T, Liu XX, Liu C, Shen F, Wang BY, Ding RR, Liu YM, Huang GY, Li WJ, Li X
Biomedical and environmental sciences : BES 2020 May 20;33(5):365-368
Biomedical and environmental sciences : BES 2020 May 20;33(5):365-368
Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice.
Huang H, Cai H, Zhang L, Hua Z, Shi J, Wei Y
International immunopharmacology 2020 Mar;80:106123
International immunopharmacology 2020 Mar;80:106123
Evaluation of the post-treatment anti-inflammatory capacity of osteoarthritic chondrocytes: An in vitro study using baicalein.
Wu CC, Chen YR, Lu DH, Hsu LH, Yang KC, Sumi S
Regenerative therapy 2020 Jun;14:177-183
Regenerative therapy 2020 Jun;14:177-183
Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice.
Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, Li X, Gao M, Tang L, Li Y
Aging 2020 Jun 24;12(12):12142-12159
Aging 2020 Jun 24;12(12):12142-12159
Blockade of periostin-dependent migration and adhesion by curcumol via inhibition of nuclear factor kappa B signaling in hepatic stellate cells.
Jia Y, Gao L, Yang X, Zhang F, Chen A, Wang S, Shao J, Tan S, Zheng S
Toxicology 2020 Jul;440:152475
Toxicology 2020 Jul;440:152475
LncRNA RP11-86H7.1 promotes airway inflammation induced by TRAPM2.5 by acting as a ceRNA of miRNA-9-5p to regulate NFKB1 in HBECS.
Zhao J, Pu J, Hao B, Huang L, Chen J, Hong W, Zhou Y, Li B, Ran P
Scientific reports 2020 Jul 14;10(1):11587
Scientific reports 2020 Jul 14;10(1):11587
LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling.
Zhang L, Yan X, Yu S, Zhong X, Tian R, Xu L, Bian X, Su J
Oncology letters 2020 Jan;19(1):753-762
Oncology letters 2020 Jan;19(1):753-762
Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway.
Yu T, Dong D, Guan J, Sun J, Guo M, Wang Q
Herz 2020 Dec;45(Suppl 1):130-138
Herz 2020 Dec;45(Suppl 1):130-138
Latcripin-7A, derivative of Lentinula edodes C(91-3), reduces migration and induces apoptosis, autophagy, and cell cycle arrest at G(1) phase in breast cancer cells.
Din SRU, Zhong M, Nisar MA, Saleem MZ, Hussain A, Khinsar KH, Alam S, Ayub G, Kanwal S, Li X, Zhang W, Wang X, Ning A, Cao J, Huang M
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Applied microbiology and biotechnology 2020 Dec;104(23):10165-10179
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in streptozotocin (STZ)-induced Alzheimer's disease rats.
Song L, Piao Z, Yao L, Zhang L, Lu Y
Experimental animals 2020 Aug 5;69(3):363-373
Experimental animals 2020 Aug 5;69(3):363-373
Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease.
Zhao J, Gao W, Cai X, Xu J, Zou D, Li Z, Hu B, Zheng Y
Theranostics 2019;9(10):2843-2855
Theranostics 2019;9(10):2843-2855
Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma.
Tian N, Shangguan W, Zhou Z, Yao Y, Fan C, Cai L
Journal of Cancer 2019;10(24):6074-6087
Journal of Cancer 2019;10(24):6074-6087
Epstein-Barr virus tegument protein BGLF2 inhibits NF-κB activity by preventing p65 Ser536 phosphorylation.
Chen T, Wang Y, Xu Z, Zou X, Wang P, Ou X, Li Y, Peng T, Chen D, Li M, Cai M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10563-10576
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2019 Sep;33(9):10563-10576
NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress.
Yang B, Figueroa DM, Hou Y, Babbar M, Baringer SL, Croteau DL, Bohr VA
Free radical biology & medicine 2019 Sep;141:47-58
Free radical biology & medicine 2019 Sep;141:47-58
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
Liang J, Zhou F, Xiong X, Zhang X, Li S, Li X, Gao M, Li Y
Aging 2019 Sep 6;11(17):7036-7050
Aging 2019 Sep 6;11(17):7036-7050
Down-regulation of taurine-up-regulated gene 1 attenuates inflammation by sponging miR-9-5p via targeting NF-κB1/p50 in multiple sclerosis.
Yue P, Jing L, Zhao X, Zhu H, Teng J
Life sciences 2019 Sep 15;233:116731
Life sciences 2019 Sep 15;233:116731
Adipose-derived mesenchymal stem cells ameliorate acute liver injury in rat model of CLP induced-sepsis via sTNFR1.
Liang H, Ding X, Yu Y, Zhang H, Wang L, Kan Q, Ma S, Guan F, Sun T
Experimental cell research 2019 Oct 1;383(1):111465
Experimental cell research 2019 Oct 1;383(1):111465
Polydatin alleviates traumatic spinal cord injury by reducing microglial inflammation via regulation of iNOS and NLRP3 inflammasome pathway.
Lv R, Du L, Liu X, Zhou F, Zhang Z, Zhang L
International immunopharmacology 2019 May;70:28-36
International immunopharmacology 2019 May;70:28-36
Antidepressant-Like Effect and Mechanism of Action of Honokiol on the Mouse Lipopolysaccharide (LPS) Depression Model.
Zhang B, Wang PP, Hu KL, Li LN, Yu X, Lu Y, Chang HS
Molecules (Basel, Switzerland) 2019 May 28;24(11)
Molecules (Basel, Switzerland) 2019 May 28;24(11)
Neuroprotective Effects of Ginsenosides against Cerebral Ischemia.
Cheng Z, Zhang M, Ling C, Zhu Y, Ren H, Hong C, Qin J, Liu T, Wang J
Molecules (Basel, Switzerland) 2019 Mar 20;24(6)
Molecules (Basel, Switzerland) 2019 Mar 20;24(6)
Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells.
Adegoke EO, Adeniran SO, Zeng Y, Wang X, Wang H, Wang C, Zhang H, Zheng P, Zhang G
Journal of applied toxicology : JAT 2019 Jun;39(6):832-843
Journal of applied toxicology : JAT 2019 Jun;39(6):832-843
Effect of dexmedetomidine on kidney injury in sepsis rats through TLR4/MyD88/NF-κB/iNOS signaling pathway.
Jin YH, Li ZT, Chen H, Jiang XQ, Zhang YY, Wu F
European review for medical and pharmacological sciences 2019 Jun;23(11):5020-5025
European review for medical and pharmacological sciences 2019 Jun;23(11):5020-5025
Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis.
Wang Y, Ai L, Hai B, Cao Y, Li R, Li H, Li Y
Physiological research 2019 Jun 30;68(3):445-455
Physiological research 2019 Jun 30;68(3):445-455
Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells.
Wu D, Zhong P, Wang J, Wang H
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Molecular and cellular biochemistry 2019 Jul;457(1-2):145-156
Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells.
Shi H, Wang XL, Quan HF, Yan L, Pei XY, Wang R, Peng XD
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Molecules (Basel, Switzerland) 2019 Jan 21;24(2)
Genistein inhibits Ang II-induced CRP and MMP-9 generations via the ER-p38/ERK1/2-PPARγ-NF-κB signaling pathway in rat vascular smooth muscle cells.
Xu L, Liu JT, Li K, Wang SY, Xu S
Life sciences 2019 Jan 1;216:140-146
Life sciences 2019 Jan 1;216:140-146
Paeonol-mediated apoptosis of hepatocellular carcinoma cells by NF-κB pathway.
Li Q, Zhang Y, Sun J, Bo Q
Oncology letters 2019 Feb;17(2):1761-1767
Oncology letters 2019 Feb;17(2):1761-1767
Protective effect of metformin on a rat model of lipopolysaccharide-induced preeclampsia.
Hu J, Zhang J, Zhu B
Fundamental & clinical pharmacology 2019 Dec;33(6):649-658
Fundamental & clinical pharmacology 2019 Dec;33(6):649-658
Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway.
Zhao R, Ying M, Gu S, Yin W, Li Y, Yuan H, Fang S, Li M
Neuroscience 2019 Dec 1;422:99-118
Neuroscience 2019 Dec 1;422:99-118
RING finger protein 10 is a potential drug target for diabetic vascular complications.
Li S, Yu G, Huang W, Wang R, Pu P, Chen M
Molecular medicine reports 2019 Aug;20(2):931-938
Molecular medicine reports 2019 Aug;20(2):931-938
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, Wang F, Zhu C, Liu W, Cheng Z, Zhu Y, Zhou L, Zhang Y, Lu M, Liu S
PLoS pathogens 2019 Aug;15(8):e1008002
PLoS pathogens 2019 Aug;15(8):e1008002
Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome.
Lin Y, Wang S, Yang Z, Gao L, Zhou Z, Yu P, Wu B
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Aug;116:108973
Investigation of the variants at the binding site of inflammatory transcription factor NF-κB in patients with end-stage renal disease.
Yang JH, Chen WT, Lee MC, Fang WH, Hsu YJ, Chin-Lin, Chen HC, Chang HL, Chen CF, Tu MY, Kuo CW, Lin YH, Hsiao PJ, Su SL
BMC nephrology 2019 Aug 5;20(1):300
BMC nephrology 2019 Aug 5;20(1):300
SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65.
Li P, Jin Y, Qi F, Wu F, Luo S, Cheng Y, Montgomery RR, Qian F
Frontiers in cellular and infection microbiology 2018;8:113
Frontiers in cellular and infection microbiology 2018;8:113
Pretreatment with Lactobacillus reuteri F-9-35 attenuates ethanol-induced gastric injury in rats.
Sun MC, Hou PP, Wang XY, Zhao CH, Cheng BJ, Wang YL, Hao HW, Zhang TH, Ye HQ
Food & nutrition research 2018;62
Food & nutrition research 2018;62
Alpha-Lipoic Acid Preconditioning and Ischaemic Postconditioning Synergistically Protect Rats from Cerebral Injury Induced by Ischemia and Reperfusion Partly via Inhibition TLR4/MyD88/ NF-κB Signaling Pathway.
Zhang J, Xiao F, Zhang L, Wang X, Lai X, Shen Y, Zhang M, Zhou B, Lang H, Yu P, Hua F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(3):1448-1460
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;51(3):1448-1460
Panax notoginseng Saponins Regulate Macrophage Polarization under Hyperglycemic Condition via NF-κB Signaling Pathway.
Zhao Y, Zheng J, Yu Y, Wang L
BioMed research international 2018;2018:9239354
BioMed research international 2018;2018:9239354
Serum and Ectopic Endometrium from Women with Endometriosis Modulate Macrophage M1/M2 Polarization via the Smad2/Smad3 Pathway.
Nie MF, Xie Q, Wu YH, He H, Zou LJ, She XL, Wu XQ
Journal of immunology research 2018;2018:6285813
Journal of immunology research 2018;2018:6285813
Losartan Ameliorates Calcium Oxalate-Induced Elevation of Stone-Related Proteins in Renal Tubular Cells by Inhibiting NADPH Oxidase and Oxidative Stress.
Qin B, Wang Q, Lu Y, Li C, Hu H, Zhang J, Wang Y, Zhu J, Zhu Y, Xun Y, Wang S
Oxidative medicine and cellular longevity 2018;2018:1271864
Oxidative medicine and cellular longevity 2018;2018:1271864
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Feng J, Chen K, Xia Y, Wu L, Li J, Li S, Wang W, Lu X, Liu T, Guo C
Drug design, development and therapy 2018;12:1837-1853
Drug design, development and therapy 2018;12:1837-1853
Effects of SB202190 on expression levels of IL-6 and NF-κB in flap ischemia-reperfusion injury.
Guo K, Ma J, Liang W
Experimental and therapeutic medicine 2018 Sep;16(3):2522-2526
Experimental and therapeutic medicine 2018 Sep;16(3):2522-2526
NKILA lncRNA promotes tumor immune evasion by sensitizing T cells to activation-induced cell death.
Huang D, Chen J, Yang L, Ouyang Q, Li J, Lao L, Zhao J, Liu J, Lu Y, Xing Y, Chen F, Su F, Yao H, Liu Q, Su S, Song E
Nature immunology 2018 Oct;19(10):1112-1125
Nature immunology 2018 Oct;19(10):1112-1125
Resveratrol inhibits monocrotaline-induced pulmonary arterial remodeling by suppression of SphK1-mediated NF-κB activation.
Shi W, Zhai C, Feng W, Wang J, Zhu Y, Li S, Wang Q, Zhang Q, Yan X, Chai L, Liu P, Chen Y, Li M
Life sciences 2018 Oct 1;210:140-149
Life sciences 2018 Oct 1;210:140-149
Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis.
Dai C, Xiao X, Li D, Tun S, Wang Y, Velkov T, Tang S
Cell death & disease 2018 Nov 26;9(12):1164
Cell death & disease 2018 Nov 26;9(12):1164
Neurotoxicity, behavioral changes and gene-expression profile of mice exposed to SnS(2) nanoflowers.
Bai D, Li Q, Wang J, Zhao J, Deng X, Yuan L, Wu P
Toxicology research 2018 Nov 1;7(6):1267-1279
Toxicology research 2018 Nov 1;7(6):1267-1279
TLR4 signaling pathway mediates the LPS/ischemia-induced expression of monocytechemotactic protein-induced protein 1 in microglia.
Chen S, Lyu C, Zhou J, Huang S, Zhang Y, Liu G, Liu K, Chen D, Hu Y, Zhou L, Gu Y
Neuroscience letters 2018 Nov 1;686:33-40
Neuroscience letters 2018 Nov 1;686:33-40
Arsenic and/or copper caused inflammatory response via activation of inducible nitric oxide synthase pathway and triggered heat shock protein responses in testis tissues of chicken.
Shao Y, Zhao H, Wang Y, Liu J, Li J, Chai H, Xing M
Environmental science and pollution research international 2018 Mar;25(8):7719-7729
Environmental science and pollution research international 2018 Mar;25(8):7719-7729
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation.
Qiao Y, Xu L, Tao X, Yin L, Qi Y, Xu Y, Han X, Tang Z, Ma X, Liu K, Peng J
Toxicology letters 2018 Mar 1;284:37-45
Toxicology letters 2018 Mar 1;284:37-45
Knockdown of SNHG15 suppresses renal cell carcinoma proliferation and EMT by regulating the NF-κB signaling pathway.
Du Y, Kong C, Zhu Y, Yu M, Li Z, Bi J, Li Z, Liu X, Zhang Z, Yu X
International journal of oncology 2018 Jul;53(1):384-394
International journal of oncology 2018 Jul;53(1):384-394
Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma.
Cheng Y, Zhao P, Wu S, Yang T, Chen Y, Zhang X, He C, Zheng C, Li K, Ma X, Xiang G
International journal of pharmaceutics 2018 Jul 10;545(1-2):261-273
International journal of pharmaceutics 2018 Jul 10;545(1-2):261-273
Human umbilical cord mesenchymal stem cell conditioned medium attenuates renal fibrosis by reducing inflammation and epithelial-to-mesenchymal transition via the TLR4/NF-κB signaling pathway in vivo and in vitro.
Liu B, Ding F, Hu D, Zhou Y, Long C, Shen L, Zhang Y, Zhang D, Wei G
Stem cell research & therapy 2018 Jan 12;9(1):7
Stem cell research & therapy 2018 Jan 12;9(1):7
Propofol protects against endotoxin-induced myocardial injury by inhibiting NF-κB-mediated inflammation.
Yang Z, Cheng F, Yan G, Xiong L, Liu H
Experimental and therapeutic medicine 2018 Feb;15(2):2032-2036
Experimental and therapeutic medicine 2018 Feb;15(2):2032-2036
Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress.
Wang Y, Hai B, Ai L, Cao Y, Li R, Li H, Li Y
Iranian journal of basic medical sciences 2018 Dec;21(12):1238-1244
Iranian journal of basic medical sciences 2018 Dec;21(12):1238-1244
Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway.
Ning C, Gao X, Wang C, Huo X, Liu Z, Sun H, Yang X, Sun P, Ma X, Meng Q, Liu K
International immunopharmacology 2018 Aug;61:266-276
International immunopharmacology 2018 Aug;61:266-276
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Bai D, Li Q, Xiong Y, Wang C, Shen P, Bai L, Yuan L, Wu P
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide.
Dang R, Zhou X, Tang M, Xu P, Gong X, Liu Y, Jiao H, Jiang P
European journal of nutrition 2018 Apr;57(3):893-906
European journal of nutrition 2018 Apr;57(3):893-906
Effect of TLR4/MyD88 signaling pathway on sepsis-associated acute respiratory distress syndrome in rats, via regulation of macrophage activation and inflammatory response.
Zhou S, Wang G, Zhang W
Experimental and therapeutic medicine 2018 Apr;15(4):3376-3384
Experimental and therapeutic medicine 2018 Apr;15(4):3376-3384
Santamarine Inhibits NF-кB and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress.
Mehmood T, Maryam A, Tian X, Khan M, Ma T
Journal of Cancer 2017;8(18):3707-3717
Journal of Cancer 2017;8(18):3707-3717
Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Acinar Cell Injury via MicroRNA-30a-5p-Mediated Inhibition of High-Temperature Requirement A/Transforming Growth Factor Beta 1 Inflammatory Signaling.
Xiang H, Tao X, Xia S, Qu J, Song H, Liu J, Shang D
Frontiers in immunology 2017;8:1488
Frontiers in immunology 2017;8:1488
RNA-sequencing dissects the transcriptome of polyploid cancer cells that are resistant to combined treatments of cisplatin with paclitaxel and docetaxel.
Wang Q, Lu F, Lan R
Molecular bioSystems 2017 Sep 26;13(10):2125-2134
Molecular bioSystems 2017 Sep 26;13(10):2125-2134
Inducible TAP1 Negatively Regulates the Antiviral Innate Immune Response by Targeting the TAK1 Complex.
Xia Z, Xu G, Yang X, Peng N, Zuo Q, Zhu S, Hao H, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2017 May 1;198(9):3690-3704
Journal of immunology (Baltimore, Md. : 1950) 2017 May 1;198(9):3690-3704
miR-15b-5p resensitizes colon cancer cells to 5-fluorouracil by promoting apoptosis via the NF-κB/XIAP axis.
Zhao C, Zhao Q, Zhang C, Wang G, Yao Y, Huang X, Zhan F, Zhu Y, Shi J, Chen J, Yan F, Zhang Y
Scientific reports 2017 Jun 23;7(1):4194
Scientific reports 2017 Jun 23;7(1):4194
Glucose variability aggravates cardiac fibrosis by altering AKT signalling path.
Ying C, Liu T, Ling H, Cheng M, Zhou X, Wang S, Mao Y, Chen L, Zhang R, Li W
Diabetes & vascular disease research 2017 Jul;14(4):327-335
Diabetes & vascular disease research 2017 Jul;14(4):327-335
p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells.
Yan XY, Zhang Y, Zhang JJ, Zhang LC, Liu YN, Wu Y, Xue YN, Lu SY, Su J, Sun LK
Cancer science 2017 Jul;108(7):1405-1413
Cancer science 2017 Jul;108(7):1405-1413
Deoxyelephantopin induces apoptosis in HepG2 cells via oxidative stress, NF-κB inhibition and mitochondrial dysfunction.
Mehmood T, Maryam A, Zhang H, Li Y, Khan M, Ma T
BioFactors (Oxford, England) 2017 Jan 2;43(1):63-72
BioFactors (Oxford, England) 2017 Jan 2;43(1):63-72
High-mobility group box 1 is overexpressed in cervical carcinoma and promotes cell invasion and migration in vitro.
Pang X, Zhang Y, Zhang S
Oncology reports 2017 Feb;37(2):831-840
Oncology reports 2017 Feb;37(2):831-840
Synergistic inhibition of tumor growth by combination treatment with drugs against different subpopulations of glioblastoma cells.
Chang CH, Liu WT, Hung HC, Gean CY, Tsai HM, Su CL, Gean PW
BMC cancer 2017 Dec 29;17(1):905
BMC cancer 2017 Dec 29;17(1):905
The p53-inducible long noncoding RNA TRINGS protects cancer cells from necrosis under glucose starvation.
Khan MR, Xiang S, Song Z, Wu M
The EMBO journal 2017 Dec 1;36(23):3483-3500
The EMBO journal 2017 Dec 1;36(23):3483-3500
Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders.
Wang H, Xu YS, Wang ML, Cheng C, Bian R, Yuan H, Wang Y, Guo T, Zhu LL, Zhou H
International journal of molecular medicine 2017 Apr;39(4):819-830
International journal of molecular medicine 2017 Apr;39(4):819-830
Herpes Simplex Virus 1 UL24 Abrogates the DNA Sensing Signal Pathway by Inhibiting NF-κB Activation.
Xu H, Su C, Pearson A, Mody CH, Zheng C
Journal of virology 2017 Apr 1;91(7)
Journal of virology 2017 Apr 1;91(7)
Hepatoprotective Effect of Quercetin on Endoplasmic Reticulum Stress and Inflammation after Intense Exercise in Mice through Phosphoinositide 3-Kinase and Nuclear Factor-Kappa B.
Tang Y, Li J, Gao C, Xu Y, Li Y, Yu X, Wang J, Liu L, Yao P
Oxidative medicine and cellular longevity 2016;2016:8696587
Oxidative medicine and cellular longevity 2016;2016:8696587
Carnosic acid alleviates chronic alcoholic liver injury by regulating the SIRT1/ChREBP and SIRT1/p66shc pathways in rats.
Gao L, Shan W, Zeng W, Hu Y, Wang G, Tian X, Zhang N, Shi X, Zhao Y, Ding C, Zhang F, Liu K, Yao J
Molecular nutrition & food research 2016 Sep;60(9):1902-11
Molecular nutrition & food research 2016 Sep;60(9):1902-11
Novel recombinant protein FlaA N/C increases tumor radiosensitivity via NF-κB signaling in murine breast cancer cells.
Xu Y, Wu D, Fan Y, Li P, Du H, Shi J, Wang D, Zhou X
Oncology letters 2016 Oct;12(4):2632-2640
Oncology letters 2016 Oct;12(4):2632-2640
Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation.
Zhang W, Yin L, Tao X, Xu L, Zheng L, Han X, Xu Y, Wang C, Peng J
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Environmental toxicology and pharmacology 2016 Jul;45:193-201
Total Flavonoids from Rosa laevigata Michx Fruit Ameliorates Hepatic Ischemia/Reperfusion Injury through Inhibition of Oxidative Stress and Inflammation in Rats.
Tao X, Sun X, Xu L, Yin L, Han X, Qi Y, Xu Y, Zhao Y, Wang C, Peng J
Nutrients 2016 Jul 8;8(7)
Nutrients 2016 Jul 8;8(7)
CD147 promotes IKK/IκB/NF-κB pathway to resist TNF-induced apoptosis in rheumatoid arthritis synovial fibroblasts.
Zhai Y, Wu B, Li J, Yao XY, Zhu P, Chen ZN
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
Journal of molecular medicine (Berlin, Germany) 2016 Jan;94(1):71-82
SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells.
Wu J, Yang C, Guo C, Li X, Yang N, Zhao L, Hang H, Liu S, Chu P, Sun Z, Sun B, Lin Y, Peng J, Han G, Wang S, Tang Z
Chemico-biological interactions 2016 Jan 25;244:94-104
Chemico-biological interactions 2016 Jan 25;244:94-104
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease.
Zeng W, Shan W, Gao L, Gao D, Hu Y, Wang G, Zhang N, Li Z, Tian X, Xu W, Peng J, Ma X, Yao J
Scientific reports 2015 Nov 3;5:16013
Scientific reports 2015 Nov 3;5:16013
Clonorchis sinensis ferritin heavy chain triggers free radicals and mediates inflammation signaling in human hepatic stellate cells.
Mao Q, Xie Z, Wang X, Chen W, Ren M, Shang M, Lei H, Tian Y, Li S, Liang P, Chen T, Liang C, Xu J, Li X, Huang Y, Yu X
Parasitology research 2015 Feb;114(2):659-70
Parasitology research 2015 Feb;114(2):659-70
Diallyl trisulfide inhibits naphthalene-induced oxidative injury and the production of inflammatory responses in A549 cells and mice.
Zhang F, Zhang Y, Wang K, Zhu X, Lin G, Zhao Z, Li S, Cai J, Cao J
International immunopharmacology 2015 Dec;29(2):326-333
International immunopharmacology 2015 Dec;29(2):326-333
Potent effects of flavonoid-rich extract from Rosa laevigata Michx fruit against hydrogen peroxide-induced damage in PC12 cells via attenuation of oxidative stress, inflammation and apoptosis.
Liu M, Xu Y, Han X, Liang C, Yin L, Xu L, Qi Y, Zhao Y, Peng J, Sun C
Molecules (Basel, Switzerland) 2014 Aug 7;19(8):11816-32
Molecules (Basel, Switzerland) 2014 Aug 7;19(8):11816-32
The hepatitis B virus X protein downregulates NF-κB signaling pathways through decreasing the Notch signaling pathway in HBx-transformed L02 cells.
Luo J, Zhou H, Wang F, Xia X, Sun Q, Wang R, Cheng B
International journal of oncology 2013 May;42(5):1636-43
International journal of oncology 2013 May;42(5):1636-43
Herpes simplex virus 1 E3 ubiquitin ligase ICP0 protein inhibits tumor necrosis factor alpha-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Zhang J, Wang K, Wang S, Zheng C
Journal of virology 2013 Dec;87(23):12935-48
Journal of virology 2013 Dec;87(23):12935-48
Herpes simplex virus 1 DNA polymerase processivity factor UL42 inhibits TNF-α-induced NF-κB activation by interacting with p65/RelA and p50/NF-κB1.
Zhang J, Wang S, Wang K, Zheng C
Medical microbiology and immunology 2013 Aug;202(4):313-25
Medical microbiology and immunology 2013 Aug;202(4):313-25
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 14220-1-AP(NFKB1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NFKB1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NFKB1. This antibody recognizes human,mouse,rat antigen. The NFKB1 antibody has been validated for the following applications: ELISA, WB, IF analysis.
