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antibody from Boster Biological Technology
Targeting: NFKB1
KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- PB9149 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-NFkB p105/p50/NFKB1 Antibody Picoband™
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for P50/NFKB1 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. P50/NFKB1 information: Molecular Weight: 105356 MW; Subcellular Localization: Nucleus. Cytoplasm. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).
- Reactivity
- Human, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references Curcumin Derivative Cur20 Attenuated Cerebral Ischemic Injury by Antioxidant Effect and HIF-1α/VEGF/TFEB-Activated Angiogenesis.
HMGB1 is a key factor for tamoxifen resistance and has the potential to predict the efficacy of CDK4/6 inhibitors in breast cancer.
Breast cancer pathogenesis is linked to the intra-tumoral estrogen sulfotransferase (hSULT1E1) expressions regulated by cellular redox dependent Nrf-2/NFκβ interplay.
The PI3K/Akt and NF-κB signaling pathways are involved in the protective effects of Lithocarpus polystachyus (sweet tea) on APAP-induced oxidative stress injury in mice.
HBOA ameliorates CCl(4)-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes.
HMGB3 modulates ROS production via activating TLR cascade in Apostichopus japonicus.
Hydrogen Sulfide Mitigates Kidney Injury in High Fat Diet-Induced Obese Mice.
Upregulation of Toll-like receptor 2 expression in colorectal cancer infected by human cytomegalovirus.
Double-stranded RNA transcribed from vector-based oligodeoxynucleotide acts as transcription factor decoy.
Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury.
Kallistatin, a novel anti-angiogenesis agent, inhibits angiogenesis via inhibition of the NF-κB signaling pathway.
MiR199b suppresses expression of hypoxia-inducible factor 1α (HIF-1α) in prostate cancer cells.
The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.
The oncogenic role of NS5A of hepatitis C virus is mediated by up-regulation of survivin gene expression in the hepatocellular cell through p53 and NF-κB pathways.
Epidermal growth factor-induced proliferation of chicken primordial germ cells: involvement of calcium/protein kinase C and NFKB1.
Cortical expression of nuclear factor kappaB after human brain contusion.
Zhang R, Zhao T, Zheng B, Zhang Y, Li X, Zhang F, Cen J, Duan S
Frontiers in pharmacology 2021;12:648107
Frontiers in pharmacology 2021;12:648107
HMGB1 is a key factor for tamoxifen resistance and has the potential to predict the efficacy of CDK4/6 inhibitors in breast cancer.
Zhang H, Wang J, Li J, Zhou X, Yin L, Wang Y, Gu Y, Niu X, Yang Y, Ji H, Zhang Q
Cancer science 2021 Apr;112(4):1603-1613
Cancer science 2021 Apr;112(4):1603-1613
Breast cancer pathogenesis is linked to the intra-tumoral estrogen sulfotransferase (hSULT1E1) expressions regulated by cellular redox dependent Nrf-2/NFκβ interplay.
Nazmeen A, Chen G, Ghosh TK, Maiti S
Cancer cell international 2020;20:70
Cancer cell international 2020;20:70
The PI3K/Akt and NF-κB signaling pathways are involved in the protective effects of Lithocarpus polystachyus (sweet tea) on APAP-induced oxidative stress injury in mice.
Yang JY, Zhong YT, Hao WN, Liu XX, Shen Q, Li YF, Ren S, Wang Z, Li W, Zhao LC
RSC advances 2020 May 10;10(31):18044-18053
RSC advances 2020 May 10;10(31):18044-18053
HBOA ameliorates CCl(4)-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Sun X, Huang X, Zhu X, Liu L, Mo S, Wang H, Wei X, Lu S, Bai F, Wang D, Lin X, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
Induction of immunosuppressive functions and NF-κB by FLIP in monocytes.
Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, Sartoris S, Solito S, Mandruzzato S, Vascotto F, Hippen KL, Mondanelli G, Grohmann U, Piro G, Carbone C, Melisi D, Lawlor RT, Scarpa A, Lamolinara A, Iezzi M, Fassan M, Bicciato S, Blazar BR, Sahin U, Murray PJ, Bronte V
Nature communications 2018 Dec 5;9(1):5193
Nature communications 2018 Dec 5;9(1):5193
HMGB3 modulates ROS production via activating TLR cascade in Apostichopus japonicus.
Lv Z, Zhang Z, Wei Z, Li C, Shao Y, Zhang W, Zhao X, Xiong J
Developmental and comparative immunology 2017 Dec;77:128-137
Developmental and comparative immunology 2017 Dec;77:128-137
Hydrogen Sulfide Mitigates Kidney Injury in High Fat Diet-Induced Obese Mice.
Wu D, Gao B, Li M, Yao L, Wang S, Chen M, Li H, Ma C, Ji A, Li Y
Oxidative medicine and cellular longevity 2016;2016:2715718
Oxidative medicine and cellular longevity 2016;2016:2715718
Upregulation of Toll-like receptor 2 expression in colorectal cancer infected by human cytomegalovirus.
Li X, Qian D, Ju F, Wang B
Oncology letters 2015 Jan;9(1):365-370
Oncology letters 2015 Jan;9(1):365-370
Double-stranded RNA transcribed from vector-based oligodeoxynucleotide acts as transcription factor decoy.
Xiao X, Gang Y, Wang H, Wang J, Zhao L, Xu L, Liu Z
Biochemical and biophysical research communications 2015 Feb 6;457(2):221-6
Biochemical and biophysical research communications 2015 Feb 6;457(2):221-6
Effect of ammonium pyrrolidine dithiocarbamate (PDTC) on NF-κB activation and CYP2E1 content of rats with immunological liver injury.
Qin JD, Cao ZH, Li XF, Kang XL, Xue Y, Li YL, Zhang D, Liu XY, Xue YZ
Pharmaceutical biology 2014 Nov;52(11):1460-6
Pharmaceutical biology 2014 Nov;52(11):1460-6
Kallistatin, a novel anti-angiogenesis agent, inhibits angiogenesis via inhibition of the NF-κB signaling pathway.
Huang KF, Huang XP, Xiao GQ, Yang HY, Lin JS, Diao Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 May;68(4):455-61
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 May;68(4):455-61
MiR199b suppresses expression of hypoxia-inducible factor 1α (HIF-1α) in prostate cancer cells.
Shang W, Chen X, Nie L, Xu M, Chen N, Zeng H, Zhou Q
International journal of molecular sciences 2013 Apr 17;14(4):8422-36
International journal of molecular sciences 2013 Apr 17;14(4):8422-36
The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells.
Leng AM, Liu T, Yang J, Cui JF, Li XH, Zhu YN, Xiong T, Zhang G, Chen Y
Cell biology international 2012 Oct 1;36(10):893-9
Cell biology international 2012 Oct 1;36(10):893-9
The oncogenic role of NS5A of hepatitis C virus is mediated by up-regulation of survivin gene expression in the hepatocellular cell through p53 and NF-κB pathways.
Jiang YF, He B, Li NP, Ma J, Gong GZ, Zhang M
Cell biology international 2011 Dec;35(12):1225-32
Cell biology international 2011 Dec;35(12):1225-32
Epidermal growth factor-induced proliferation of chicken primordial germ cells: involvement of calcium/protein kinase C and NFKB1.
Ge C, Yu M, Petitte JN, Zhang C
Biology of reproduction 2009 Mar;80(3):528-36
Biology of reproduction 2009 Mar;80(3):528-36
Cortical expression of nuclear factor kappaB after human brain contusion.
Hang CH, Chen G, Shi JX, Zhang X, Li JS
Brain research 2006 Sep 13;1109(1):14-21
Brain research 2006 Sep 13;1109(1):14-21
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-NFkB p105/P50 Picoband antibody, PB9149-1.jpgAll lanes: Anti NFKBP105 (PB9149) at 0.5ug/mlWB: Recombinant Human NFKBP105 Protein 0.5ngPredicted bind size: 40KDObserved bind size: 40KD
- Additional image
