10-6021
antibody from ABEOMICS Inc.
Targeting: NFKB1
KBF1, NF-kappaB, NF-kB1, NFkappaB, NFKB-p50, p105, p50
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10-6021 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-p105/p50 Antibody
- Antibody type
- Monoclonal
- Description
- p50 (KBF1, p105, EBP-1, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B) family of transcription factors plays important roles in various biological processes including apoptosis, stress response, immunity, and inflammation. Activation of p50 regulates the expression of inflammatory genes crucially involved in the pathogenesis of inflammatory diseases. It governs the expression of adhesion molecules that play a pivotal role in leukocyte-endothelium interactions. p50 activation plays an essential role in the activation of mesangial cells and macrophages through the transcriptional induction of inflammatory mediators of glomerular inflammation and injury.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant p50 pr
otein (amino acids 1-200) was used
as the immunogen for this antibody.- Isotype
- IgG
- Antibody clone number
- ABM20H5
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of p50. Anti-p50 antibody (Clone: ABM20H5) was tested at 1 µg/ml on THP1, Ramos, Jurkat and Raji lysates.
- Protocol
- Protocol