Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB6510 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB6510, RRID:AB_10696251
- Product name
- HAX1 monoclonal antibody, clone AT3C5
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised aganist full length recombinant HAX1.
- Isotype
- IgG
- Antibody clone number
- AT3C5
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease).
Evidence that HAX-1 is an interleukin-1 alpha N-terminal binding protein.
Klein C, Grudzien M, Appaswamy G, Germeshausen M, Sandrock I, Schäffer AA, Rathinam C, Boztug K, Schwinzer B, Rezaei N, Bohn G, Melin M, Carlsson G, Fadeel B, Dahl N, Palmblad J, Henter JI, Zeidler C, Grimbacher B, Welte K
Nature genetics 2007 Jan;39(1):86-92
Nature genetics 2007 Jan;39(1):86-92
Evidence that HAX-1 is an interleukin-1 alpha N-terminal binding protein.
Yin H, Morioka H, Towle CA, Vidal M, Watanabe T, Weissbach L
Cytokine 2001 Aug 7;15(3):122-37
Cytokine 2001 Aug 7;15(3):122-37
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
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- Experimental details
- Cell lysates of HeLa (30 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with HAX1 monoclonal antibody, clone AT3C5 (Cat # MAB6510) (1 : 1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.