Ab101943

antibody from Aladdin Scientific

Targeting: EFNA1 ECKLG, EPLG1, GMAN, LERK1, TNFAIP4

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Validation data

Product number: Ab101943 - Provider product page
Provider: Aladdin Scientific
Product name: Recombinant Ephrin A1 Antibody
Antibody type: Recombinant
Description: Rabbit anti Human Ephrin A1 Antibody, Recombinant, could be used for WB and so on.Application:WB: 1/500-1/1000Protein FunctionPlays an important role in angiogenesis and tumor neovascularization. The recruitement of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly (By similarity). Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cones.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: AA 25-45
Vial size: 100_l,10_l,1ml,50_l
Concentration: 0,45 mg/ml
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

EFNA1 protein structure - Ab101943 shown in red.