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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB4726 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4726, RRID:AB_1575651
- Product name
- ICOS polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ICOS.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references PI3-kinase and MAP-kinase signaling cascades in AILIM/ICOS- and CD28-costimulated T-cells have distinct functions between cell proliferation and IL-10 production.
Expression and function of the co-stimulator H4/ICOS on activated T cells of patients with rheumatoid arthritis.
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors.
Okamoto N, Tezuka K, Kato M, Abe R, Tsuji T
Biochemical and biophysical research communications 2003 Oct 24;310(3):691-702
Biochemical and biophysical research communications 2003 Oct 24;310(3):691-702
Expression and function of the co-stimulator H4/ICOS on activated T cells of patients with rheumatoid arthritis.
Okamoto T, Saito S, Yamanaka H, Tomatsu T, Kamatani N, Ogiuchi H, Uchiyama T, Yagi J
The Journal of rheumatology 2003 Jun;30(6):1157-63
The Journal of rheumatology 2003 Jun;30(6):1157-63
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors.
Riley JL, Mao M, Kobayashi S, Biery M, Burchard J, Cavet G, Gregson BP, June CH, Linsley PS
Proceedings of the National Academy of Sciences of the United States of America 2002 Sep 3;99(18):11790-5
Proceedings of the National Academy of Sciences of the United States of America 2002 Sep 3;99(18):11790-5
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- The ICOS polyclonal antibody (Cat # PAB4726) is used in Western blot to detect ICOS in HL-60 cell lysate.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with ICOS polyclonal antibody (Cat # PAB4726) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
