26056-1-AP

antibody from Proteintech Group

Targeting: EZR VIL2

Provider product page for 26056-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [20]
Comments [0]
Validations
Western blot [1]

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Product number: 26056-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#26056-1-AP, RRID:AB_2722561
Product name: Ezrin antibody
Antibody type: Polyclonal
Description: KD/KO validated Ezrin antibody (Cat. #26056-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

EZR protein structure - 26056-1-AP shown in red.

Submitted references PODXL2 Promotes Cholangiocarcinoma Progression via Interactions with Ezrin and Activation of the MAPK/ERK1/2 and PI3K/AKT Signaling Pathways.

Meng Y, Zhang Y, Wei F, Zhang R, Li Z, Shen Y, Yan H, Wu J
Digestive diseases and sciences 2026 Mar 19;

RCN3 functions as a tumor promoter in colorectal cancer by modulating the GRP78-PI3K-AKT signaling pathway.

Huang M, Qin B, Xie Z, Zhou R, Lin Z, Zhou L, Han Z, Liu S, Zhuang K
Oncogene 2025 Oct;44(40):3850-3863

The Tumor-Suppressive Role of miR-204-5p Through Targeting Ezrin in Breast Cancer: Experimental Evidence From Cell Lines and Clinical Samples.

Dong T, Zhou H, Tang J
Clinical breast cancer 2025 Jul;25(5):e588-e596

Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies.

Smith CEL, Streets AJ, Lake AVR, Natarajan S, Best SK, Szymanska K, Karwatka M, Stevenson T, Trowbridge R, Grant G, Grellscheid SN, Foster R, Morrison CG, Mavria G, Bond J, Ong ACM, Johnson CA
Communications medicine 2025 Apr 19;5(1):129

Nebulization of Hypoxic hUCMSC-EVs Attenuates Airway Epithelial Barrier Defects in Chronic Asthma Mice by Transferring CAV-1.

Luo X, Wang Y, Mao Y, Xu X, Gu W, Li W, Mao C, Zheng T, Dong L
International journal of nanomedicine 2024;19:10941-10959

Intercellular adhesion molecule-1 suppresses TMZ chemosensitivity in acquired TMZ-resistant gliomas by increasing assembly of ABCB1 on the membrane.

Zhang X, Tan Y, Li T, Tan D, Fu B, Yang M, Chen Y, Cao M, Xuan C, Du Q, Hu R, Wang Q
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Sep;76:101112

DOCK1 regulates the malignant biological behavior of endometrial cancer through c-Raf/ERK pathway.

Xie S, Jin Y, Wang J, Li J, Peng M, Zhu X
BMC cancer 2024 Mar 4;24(1):296

Pemetrexed alleviates piglet diarrhea by blocking the interaction between porcine epidemic diarrhea virus nucleocapsid protein and Ezrin.

Zhang S, Wang J, Liu X, Kan Z, Zhang Y, Niu Z, Hu X, Zhang L, Zhang X, Song Z
Journal of virology 2024 Jan 23;98(1):e0162523

Analysis of the GFP-labelled β-dystroglycan interactome in HEK-293 transfected cells reveals novel intracellular networks.

Sciandra F, Desiderio C, Vincenzoni F, Viscuso S, Bozzi M, Hübner W, Jimenez-Gutierrez GE, Cisneros B, Brancaccio A
Biochemical and biophysical research communications 2024 Apr 9;703:149656

Cotranslational interaction of human EBP50 and ezrin overcomes masked binding site during complex assembly.

Khan K, Long B, Baleanu-Gogonea C, Gogonea V, Deshpande GM, Vasu K, Fox PL
Proceedings of the National Academy of Sciences of the United States of America 2022 Feb 15;119(7)

Selective vulnerability of tripartite synapses in amyotrophic lateral sclerosis.

Broadhead MJ, Bonthron C, Waddington J, Smith WV, Lopez MF, Burley S, Valli J, Zhu F, Komiyama NH, Smith C, Grant SGN, Miles GB
Acta neuropathologica 2022 Apr;143(4):471-486

circCDYL2, Overexpressed in Highly Migratory Colorectal Cancer Cells, Promotes Migration by Binding to Ezrin.

Li X, Wang J, Long H, Lin W, Wang H, Chen Y, Yuan Q, Li X
Frontiers in oncology 2021;11:716073

Bidirectional Tumor-Promoting Activities of Macrophage Ezrin.

Khan K, Long B, Deshpande GM, Fox PL
International journal of molecular sciences 2020 Oct 19;21(20)

Role of mTOR signaling in the regulation of high glucose-induced podocyte injury.

Li Q, Zeng Y, Jiang Q, Wu C, Zhou J
Experimental and therapeutic medicine 2019 Apr;17(4):2495-2502

Ciliary neurotrophic factor (CNTF) protects retinal cone and rod photoreceptors by suppressing excessive formation of the visual pigments.

Li S, Sato K, Gordon WC, Sendtner M, Bazan NG, Jin M
The Journal of biological chemistry 2018 Sep 28;293(39):15256-15268

Gq activity- and β-arrestin-1 scaffolding-mediated ADGRG2/CFTR coupling are required for male fertility.

Zhang DL, Sun YJ, Ma ML, Wang YJ, Lin H, Li RR, Liang ZL, Gao Y, Yang Z, He DF, Lin A, Mo H, Lu YJ, Li MJ, Kong W, Chung KY, Yi F, Li JY, Qin YY, Li J, Thomsen ARB, Kahsai AW, Chen ZJ, Xu ZG, Liu M, Li D, Yu X, Sun JP
eLife 2018 Feb 2;7

Ezrin/NF-κB Pathway Regulates EGF-induced Epithelial-Mesenchymal Transition (EMT), Metastasis, and Progression of Osteosarcoma.

Liu P, Yang P, Zhang Z, Liu M, Hu S
Medical science monitor : international medical journal of experimental and clinical research 2018 Apr 9;24:2098-2108

Podoplanin increases the migration of human fibroblasts and affects the endothelial cell network formation: A possible role for cancer-associated fibroblasts in breast cancer progression.

Suchanski J, Tejchman A, Zacharski M, Piotrowska A, Grzegrzolka J, Chodaczek G, Nowinska K, Rys J, Dziegiel P, Kieda C, Ugorski M
PloS one 2017;12(9):e0184970

Quantitative Proteomic analysis on Activated Hepatic Stellate Cells reversion Reveal STAT1 as a key regulator between Liver Fibrosis and recovery.

Zhang H, Chen F, Fan X, Lin C, Hao Y, Wei H, Lin W, Jiang Y, He F
Scientific reports 2017 Mar 21;7:44910

Regulation of CD44 expression and focal adhesion by Golgi phosphatidylinositol 4-phosphate in breast cancer.

Ijuin T, Takeuchi Y, Shimono Y, Fukumoto M, Tokuda E, Takenawa T
Cancer science 2016 Jul;107(7):981-90

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 26056-1-AP( Ezrin Antibody) at dilution of 1:5000
Validation comment: WB
Appendix: 26056-1-AP.pdf

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