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- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 21026-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21026-1-AP, RRID:AB_10732843
- Product name
- TRIM46 antibody
- Antibody type
- Polyclonal
- Description
- TRIM46 antibody (Cat. #21026-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Trim46 knockout impaired neuronal architecture and caused hypoactive behavior in rats.
TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination.
Multilayered regulations of alternative splicing, NMD, and protein stability control temporal induction and tissue-specific expression of TRIM46 during axon formation.
TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination.
Tripartite Motif-Containing 46 Promotes Viability and Inhibits Apoptosis of Osteosarcoma Cells by Activating NF-B Signaling Through Ubiquitination of PPAR.
The Spatiotemporal Construction of the Axon Initial Segment via KIF3/KAP3/TRIM46 Transport under MARK2 Signaling.
Mmu-miR-1894-3p Inhibits Cell Proliferation and Migration of Breast Cancer Cells by Targeting Trim46.
Guan F, Gao S, Sheng H, Ma Y, Chen W, Qi X, Zhang X, Gao X, Pang S, Zhang L, Zhang L
Developmental dynamics : an official publication of the American Association of Anatomists 2024 Jul;253(7):659-676
Developmental dynamics : an official publication of the American Association of Anatomists 2024 Jul;253(7):659-676
TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination.
Shen H, Gong Q, Zhang J, Wang H, Qiu Q, Zhang J, Luo D
Eye and vision (London, England) 2022 Sep 5;9(1):35
Eye and vision (London, England) 2022 Sep 5;9(1):35
Multilayered regulations of alternative splicing, NMD, and protein stability control temporal induction and tissue-specific expression of TRIM46 during axon formation.
Vuong JK, Ergin V, Chen L, Zheng S
Nature communications 2022 Apr 19;13(1):2081
Nature communications 2022 Apr 19;13(1):2081
TRIM46 contributes to high glucose-induced ferroptosis and cell growth inhibition in human retinal capillary endothelial cells by facilitating GPX4 ubiquitination.
Zhang J, Qiu Q, Wang H, Chen C, Luo D
Experimental cell research 2021 Oct 15;407(2):112800
Experimental cell research 2021 Oct 15;407(2):112800
Tripartite Motif-Containing 46 Promotes Viability and Inhibits Apoptosis of Osteosarcoma Cells by Activating NF-B Signaling Through Ubiquitination of PPAR.
Jiang W, Cai X, Xu T, Liu K, Yang D, Fan L, Li G, Yu X
Oncology research 2020 Sep 1;28(4):409-421
Oncology research 2020 Sep 1;28(4):409-421
The Spatiotemporal Construction of the Axon Initial Segment via KIF3/KAP3/TRIM46 Transport under MARK2 Signaling.
Ichinose S, Ogawa T, Jiang X, Hirokawa N
Cell reports 2019 Aug 27;28(9):2413-2426.e7
Cell reports 2019 Aug 27;28(9):2413-2426.e7
Mmu-miR-1894-3p Inhibits Cell Proliferation and Migration of Breast Cancer Cells by Targeting Trim46.
Zhang L, Li X, Dong W, Sun C, Guo D, Zhang L
International journal of molecular sciences 2016 Apr 22;17(4)
International journal of molecular sciences 2016 Apr 22;17(4)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse lung tissue were subjected to SDS PAGE followed by western blot with 21026-1-AP(TRIM46 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TRIM46 antibody 21026-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
