ABIN951572

antibody from antibodies-online

Targeting: CLK2

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN951572

Provider

antibodies-online

Product name

anti-CDC-Like Kinase 2 (CLK2) (AA 290-319), (Middle Region) antibody

Antibody type

Polyclonal

Description

Affinity chromatography on Protein A

Reactivity

Human

Host

Rabbit

Epitope

AA 290-319, Middle Region

Vial size

0.4 mL

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Phosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiation.

Nam SY, Seo HH, Park HS, An S, Kim JY, Yang KH, Kim CS, Jeong M, Jin YW
The Journal of biological chemistry 2010 Oct 8;285(41):31157-63

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Cdc2-like kinases and DNA topoisomerase I regulate alternative splicing of tissue factor in human endothelial cells.

Eisenreich A, Bogdanov VY, Zakrzewicz A, Pries A, Antoniak S, Poller W, Schultheiss HP, Rauch U
Circulation research 2009 Mar 13;104(5):589-99

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HCLK2 is required for activity of the DNA damage response kinase ATR.

Rendtlew Danielsen JM, Larsen DH, Schou KB, Freire R, Falck J, Bartek J, Lukas J
The Journal of biological chemistry 2009 Feb 13;284(7):4140-7

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Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines.

Castle JC, Zhang C, Shah JK, Kulkarni AV, Kalsotra A, Cooper TA, Johnson JM
Nature genetics 2008 Dec;40(12):1416-25

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB