10849-1-AP

antibody from Proteintech Group

Targeting: FOXO3 AF6q21, FKHRL1, FOXO2, FOXO3A

Provider product page for 10849-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [98]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

Submit

Product number: 10849-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#10849-1-AP, RRID:AB_2247214
Product name: FOXO3A antibody
Antibody type: Polyclonal
Description: KD/KO validated FOXO3A antibody (Cat. #10849-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

FOXO3 protein structure - 10849-1-AP shown in red.

Submitted references EMX2 inhibits clear cell renal cell carcinoma progress via modulating Akt/FOXO3a pathway.

Zhou X, Dong S, Zhou Y, He Z, Zhang Z, Liao L, Zou B, Zheng X, Peng K, Duan X
Molecular carcinogenesis 2024 May;63(5):951-961

Indole-3-carbinol ameliorates ovarian damage in female old mice through Nrf2/HO-1 pathway activation.

Hu H, Li F, Zhu F, Li J, Wang S, He Z, Chen J, Cheng L, Zhong F
Biochemical pharmacology 2024 May;223:116193

d-galactose causes embryonic development arrest and placental development disorders in mice by increasing ROS and inhibiting SIRT1/FOXO3a axis.

Yin L, Niu Y, Zheng X, Chu J, Ma T
Placenta 2024 May;150:52-61

Lysophosphatidic Acid Stimulates Mitogenic Activity and Signaling in Human Neuroblastoma Cells through a Crosstalk with Anaplastic Lymphoma Kinase.

Dedoni S, Olianas MC, Onali P
Biomolecules 2024 May 28;14(6)

The role of microRNA-142a in Toxoplasma gondii infection-induced downregulation of Foxp3: implications for adverse pregnancy outcomes.

Zhong Y, Cao Y, Geng X, Yang S, Qian T, Liu C, Chen J
BMC infectious diseases 2024 May 13;24(1):490

Neuroprotective effects of polyphyllin VI against rotenone-induced toxicity in SH-SY5Y cells.

Li L, Chen Z, Hao C
Brain research 2024 May 1;1830:148824

Fangji Fuling Decoction Alleviates Sepsis by Blocking MAPK14/FOXO3A Signaling Pathway.

Wang Y, Chen MQ, Dai LF, Zhang HD, Wang X
Chinese journal of integrative medicine 2024 Mar;30(3):230-242

Loss of FoxO1 activates an alternate mechanism of mitochondrial quality control for healthy adipose browning.

Shi L, Yang J, Tao Z, Zheng L, Bui TF, Alonso RL, Yue F, Cheng Z
Clinical science (London, England : 1979) 2024 Mar 20;138(6):371-385

Berberine alleviates contrast-induced nephropathy by activating Akt/Foxo3a/Nrf2 signalling pathway.

Wang W, Yu R, Wu C, Li Q, Chen J, Xiao Y, Chen H, Song J, Ji M, Zuo Z
Journal of cellular and molecular medicine 2024 Jan;28(1):e18016

Maimendong decoction regulates M2 macrophage polarization to suppress pulmonary fibrosis via PI3K/Akt/FOXO3a signalling pathway-mediated fibroblast activation.

Shuangshuang H, Mengmeng S, Lan Z, Fang Z, Yu L
Journal of ethnopharmacology 2024 Jan 30;319(Pt 3):117308

Core fucosylation regulates the ovarian response via FSH receptor during follicular development.

Wang T, Zhang Z, Qu C, Song W, Li M, Shao X, Fukuda T, Gu J, Taniguchi N, Li W
Journal of advanced research 2024 Jan 26;

Response of lipid metabolism, energy supply, and cell fate in yellowstripe goby (Mugilogobius chulae) exposed to environmentally relevant concentrations atorvastatin.

Zhao Y, Duan C, Zhang H, Gong W, Wang Y, Ren J, Nie X, Li J
Environmental pollution (Barking, Essex : 1987) 2024 Jan 15;341:122991

Dendrobium officinale Polysaccharides as a Natural Functional Component for Acetic-Acid-Induced Gastric Ulcers in Rats.

Zhang M, Xu L, Chen L, Wu H, Jia L, Zhu H
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)

Berberine ameliorates contrast-induced acute kidney injury by regulating HDAC4-FoxO3a axis-induced autophagy: In vivo and in vitro.

Zuo Z, Li Q, Zhou S, Yu R, Wu C, Chen J, Xiao Y, Chen H, Song J, Pan Y, Wang W
Phytotherapy research : PTR 2024 Apr;38(4):1761-1780

Low-dose deoxynivalenol exposure inhibits hepatic mitophagy and hesperidin reverses this phenomenon by activating SIRT1.

Chen H, Xin W, Jiang J, Shan A, Ma J
Journal of hazardous materials 2024 Apr 15;468:133854

Combined therapy of dabrafenib and an anti-HER2 antibody-drug conjugate for advanced BRAF-mutant melanoma.

Li W, Zheng C, Xu X, Xia Y, Zhang K, Huang A, Zhang X, Zheng Y, Chen G, Zhang S
Cellular & molecular biology letters 2024 Apr 10;29(1):50

The role of miR-222-2p in exosomes secreted by hexavalent chromium-induced premature senescent hepatocytes as a SASP component.

Ma Y, Li S, Ye S, Luo S, Wei L, Su Y, Zeng Y, Shi Y, Bian H, Xiao F
Environmental pollution (Barking, Essex : 1987) 2024 Apr 1;346:123535

Luteolin inhibits triple-negative breast cancer by inducing apoptosis and autophagy through SGK1-FOXO3a-BNIP3 signaling.

Wu L, Lin Y, Gao S, Wang Y, Pan H, Wang Z, Pozzolini M, Yang F, Zhang H, Yang Y, Xiao L, Xu Y
Frontiers in pharmacology 2023;14:1200843

Optineurin tunes outside-in signaling to regulate lysosome biogenesis and phagocytic clearance in the retina.

Tan LX, Germer CJ, Thamban T, La Cunza N, Lakkaraju A
Current biology : CB 2023 Sep 25;33(18):3805-3820.e7

Proteomic analysis of uterine lavage fluid of dairy cows at different time after delivery by mass spectrometry.

Jiang X, Li Z, Chang X, Huang C, Qiu R, Wang A, Lin P, Tang K, Chen H, Zhou D, Jin Y
Theriogenology 2023 Sep 1;207:31-48

3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis.

Mu M, Zhang Q, Zhao C, Li X, Chen Z, Sun X, Yu J
Cancer gene therapy 2023 Oct;30(10):1414-1425

Zigui-Yichong-Fang protects against cyclophosphamide-induced premature ovarian insufficiency via the SIRT1/Foxo3a pathway.

Xiu Z, Tang S, Kong P, Yan M, Tong X, Liu X, Liang X, Li R, Duan Y
Journal of ethnopharmacology 2023 Oct 5;314:116608

Resveratrol reduces ROS-induced ferroptosis by activating SIRT3 and compensating the GSH/GPX4 pathway.

Wang X, Shen T, Lian J, Deng K, Qu C, Li E, Li G, Ren Y, Wang Z, Jiang Z, Sun X, Li X
Molecular medicine (Cambridge, Mass.) 2023 Oct 19;29(1):137

Metformin Suppresses Stemness of Non-Small-Cell Lung Cancer Induced by Paclitaxel through FOXO3a.

Tang Z, Zhang Y, Yu Z, Luo Z
International journal of molecular sciences 2023 Nov 22;24(23)

Morusinol Extracted from Morus alba Inhibits Cell Proliferation and Induces Autophagy via FOXO3a Nuclear Accumulation-Mediated Cholesterol Biosynthesis Obstruction in Colorectal Cancer.

Zhang X, Dong Z, Yang Y, Liu C, Li J, Sun W, Zhu Y, Shen Y, Wang Z, Lü M, Cui H
Journal of agricultural and food chemistry 2023 Nov 1;71(43):16016-16031

Resistance exercise alleviates dexamethasone-induced muscle atrophy via Sestrin2/MSTN pathway in C57BL/6J mice.

Yang Y, Yang X, Huang Y, Liu S, Niu Y, Fu L
Experimental cell research 2023 Nov 1;432(1):113779

Exercise mitigates Dapagliflozin-induced skeletal muscle atrophy in STZ-induced diabetic rats.

Yang X, Wang L, Zhang L, Zhai X, Sheng X, Quan H, Lin H
Diabetology & metabolic syndrome 2023 Jul 12;15(1):154

SGK2 promotes prostate cancer metastasis by inhibiting ferroptosis via upregulating GPX4.

Cheng L, He Q, Liu B, Chen L, Lv F, Li X, Li Y, Liu C, Song Y, Xing Y
Cell death & disease 2023 Jan 31;14(1):74

The miR-27a-3p/FTO axis modifies hypoxia-induced malignant behaviors of glioma cells.

Du P, Meng L, Liao X, Liu Y, Mo X, Gong M, Liao Y
Acta biochimica et biophysica Sinica 2023 Jan 25;55(1):103-116

The Investigation of the Molecular Mechanism of Morinda officinalis How in the Treatment of Heart Failure.

Wang A, Guo Y, Ding S, Yu Y, Yuan Z, Zhang H, Liu Y
Frontiers in bioscience (Landmark edition) 2023 Feb 24;28(2):34

Toxicity assessment of organophosphate flame retardant triphenyl phosphate (TPHP) on intestines in mice.

Peng C, Zhang X, Chen Y, Wang L
Ecotoxicology and environmental safety 2023 Dec;268:115685

Melatonin alleviates pyroptosis by regulating the SIRT3/FOXO3α/ROS axis and interacting with apoptosis in Atherosclerosis progression.

Cong L, Liu X, Bai Y, Qin Q, Zhao L, Shi Y, Bai Y, Guo Z
Biological research 2023 Dec 2;56(1):62

miR-342-5p promotes vascular smooth muscle cell phenotypic transition through a negative-feedback regulation of Notch signaling via targeting FOXO3.

Wen T, Duan Y, Gao D, Zhang X, Zhang X, Liang L, Yang Z, Zhang P, Zhang J, Sun J, Feng Y, Zheng Q, Han H, Yan X
Life sciences 2023 Aug 1;326:121828

Astaxanthin promotes mitochondrial biogenesis and antioxidant capacity in chronic high-intensity interval training.

Wang Y, Chen X, Baker JS, Davison GW, Xu S, Zhou Y, Bao X
European journal of nutrition 2023 Apr;62(3):1453-1466

Ursolic Acid Alleviates Cancer Cachexia and Prevents Muscle Wasting via Activating SIRT1.

Tao W, Ouyang Z, Liao Z, Li L, Zhang Y, Gao J, Ma L, Yu S
Cancers 2023 Apr 20;15(8)

Ketone Body β-Hydroxybutyrate Prevents Myocardial Oxidative Stress in Septic Cardiomyopathy.

Ji L, He Q, Liu Y, Deng Y, Xie M, Luo K, Cai X, Zuo Y, Wu W, Li Q, Zhou R, Li T
Oxidative medicine and cellular longevity 2022;2022:2513837

FOXO3 mutation predicting gefitinib-induced hepatotoxicity in NSCLC patients through regulation of autophagy.

Guan S, Chen X, Chen Y, Wan G, Su Q, Liang H, Yang Y, Fang W, Huang Y, Zhao H, Zhuang W, Liu S, Wang F, Feng W, Zhang X, Huang M, Wang X, Zhang L
Acta pharmaceutica Sinica. B 2022 Sep;12(9):3639-3649

Daidzein alleviates doxorubicin-induced heart failure via the SIRT3/FOXO3a signaling pathway.

Li H, Zhang M, Wang Y, Gong K, Yan T, Wang D, Meng X, Yang X, Chen Y, Han J, Duan Y, Zhang S
Food & function 2022 Sep 22;13(18):9576-9588

Selenium-sensitive histone deacetylase 2 is required for forkhead box O3A and regulates extracellular matrix metabolism in cartilage.

Zhao Y, Guo Y, Sun M, Hussion S, Zheng Y, Huang H, Huo X, Zhao Y, Zhang F, Han Y, Ning Q, Xu P, Sun J, Lu S
Journal of bone and mineral metabolism 2022 Nov;40(6):914-926

Exercise attenuates angiotensinⅡ-induced muscle atrophy by targeting PPARγ/miR-29b.

Liu Q, Chen L, Liang X, Cao Y, Zhu X, Wang S, Li J, Gao J, Xiao J
Journal of sport and health science 2022 Nov;11(6):696-707

Recombinant P40 protein of Schistosoma japonicum inhibits TREM-1 expression in RAW264.7 cells via FOXO3a.

Shen P, Zhang T, Chen G, Zhang B, Huang A, Duan L, Zhu D, Chen J, Wang J, Duan Y
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 May;149:112826

Small extracellular vesicle-mediated miR-320e transmission promotes osteogenesis in OPLL by targeting TAK1.

Xu C, Zhang Z, Liu N, Li L, Zhong H, Wang R, Shi Q, Zhang Z, Wei L, Hu B, Zhang H, Shen X, Wang Y, Liu Y, Yuan W
Nature communications 2022 May 5;13(1):2467

RBM47/SNHG5/FOXO3 axis activates autophagy and inhibits cell proliferation in papillary thyroid carcinoma.

Qin Y, Sun W, Wang Z, Dong W, He L, Zhang T, Lv C, Zhang H
Cell death & disease 2022 Mar 25;13(3):270

Virus-induced FoxO factor facilitates replication of human cytomegalovirus.

Sleman S
Archives of virology 2022 Jan;167(1):109-121

Solasonine relieves sevoflurane-induced neurotoxicity via activating the AMP-activated protein kinase/FoxO3a pathway.

Zhang H, Yan L
Human & experimental toxicology 2022 Jan-Dec;41:9603271211069984

Cordycepin, a major bioactive component of Cordyceps militaris, ameliorates diabetes-induced testicular damage through the Sirt1/Foxo3a pathway.

Huang T, Zhou Y, Lu X, Tang C, Ren C, Bao X, Deng Z, Cao X, Zou J, Zhang Q, Ma B
Andrologia 2022 Feb;54(1):e14294

A detrimental role of NLRP6 in host iron metabolism during Salmonella infection.

Deng Q, Yang S, Sun L, Huang K, Dong K, Zhu Y, Cao Y, Li Y, Wu S, Huang R
Redox biology 2022 Feb;49:102217

MicroRNA-122-5p promotes renal fibrosis and injury in spontaneously hypertensive rats by targeting FOXO3.

Liu Y, Dong ZJ, Song JW, Liang LR, Sun LL, Liu XY, Miao R, Xu YL, Li XT, Zhang MW, Zhang ZZ, Zhong JC
Experimental cell research 2022 Feb 15;411(2):113017

Inhibition of cell proliferation by Tas of foamy viruses through cell cycle arrest or apoptosis underlines the different mechanisms of virus-host interactions.

Jie W, Rui-Fen Z, Zhong-Xiang H, Yan W, Wei-Na L, Yong-Ping M, Jing S, Jing-Yi C, Wan-Hong L, Xiao-Hua H, Zhi L, Yan S
Virulence 2022 Dec;13(1):342-354

A novel combination treatment of antiADAM17 antibody and erlotinib to overcome acquired drug resistance in non-small cell lung cancer through the FOXO3a/FOXM1 axis.

Li J, Chen P, Wu Q, Guo L, Leong KW, Chan KI, Kwok HF
Cellular and molecular life sciences : CMLS 2022 Dec 2;79(12):614

Danggui Buxue Tang Rescues Folliculogenesis and Ovarian Cell Apoptosis in Rats with Premature Ovarian Insufficiency.

Wang L, Liu J, Nie G, Li Y, Yang H
Evidence-based complementary and alternative medicine : eCAM 2021;2021:6614302

β-hydroxybutyrate Alleviates Learning and Memory Impairment Through the SIRT1 Pathway in D-Galactose-Injured Mice.

Yang X, Wang R, Zhou H, Wang L, Wang R, Li H, Tan B, Wu Q, Xu X, Cui L, Li Z, Li H
Frontiers in pharmacology 2021;12:751028

Stimulation of ROS Generation by Extract of Warburgia ugandensis Leading to G(0)/G(1) Cell Cycle Arrest and Antiproliferation in A549 Cells.

Zhang YL, Chen GL, Liu Y, Zhuang XC, Guo MQ
Antioxidants (Basel, Switzerland) 2021 Sep 30;10(10)

The protective effects of resveratrol pretreatment in cyclophosphamide-induced rat ovarian injury: an vivo study.

Nie Z, Zhang L, Chen W, Zhang Y, Wang W, Hua R, Zhang T, Zhao C, Gong M, Wu H
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2021 Oct;37(10):914-919

Adiponectin regulates osteocytic MLO-Y4 cell apoptosis in a high-glucose environment through the AMPK/FoxO3a signaling pathway.

Zeng Y, Liang H, Guo Y, Feng Y, Yao Q
Journal of cellular physiology 2021 Oct;236(10):7088-7096

Activation of angiotensin-converting enzyme 2/angiotensin (1-7)/mas receptor axis triggers autophagy and suppresses microglia proinflammatory polarization via forkhead box class O1 signaling.

Dang R, Yang M, Cui C, Wang C, Zhang W, Geng C, Han W, Jiang P
Aging cell 2021 Oct;20(10):e13480

MiR-223-3p targets FOXO3a to inhibit radiosensitivity in prostate cancer by activating glycolysis.

Zhou K, Wei Y, Li X, Yang X
Life sciences 2021 Oct 1;282:119798

Methionine-chelated Zn promotes anabolism by integrating mTOR signal and autophagy pathway in juvenile yellow catfish.

Wu K, Chen GH, Hogstrand C, Ling SC, Wu LX, Luo Z
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2021 May;65:126732

RANKL Mediates Muscle Atrophy and Dysfunction in a Cigarette Smoke-induced Model of Chronic Obstructive Pulmonary Disease.

Xiong J, Le Y, Rao Y, Zhou L, Hu Y, Guo S, Sun Y
American journal of respiratory cell and molecular biology 2021 May;64(5):617-628

PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.

Yin S, Liu L, Brobbey C, Palanisamy V, Ball LE, Olsen SK, Ostrowski MC, Gan W
Nature communications 2021 Jun 8;12(1):3444

Early-senescent bone marrow mesenchymal stem cells promote C2C12 cell myogenic differentiation by preventing the nuclear translocation of FOXO3.

Che J, Xu C, Wu Y, Jia P, Han Q, Ma Y, Wang X, Du Y, Zheng Y
Life sciences 2021 Jul 15;277:119520

Syringin exerts neuroprotective effects in a rat model of cerebral ischemia through the FOXO3a/NF-κB pathway.

Tan J, Luo J, Meng C, Jiang N, Cao J, Zhao J
International immunopharmacology 2021 Jan;90:107268

Xiaoyaosan decoction alleviated rat liver fibrosis via the TGFβ/Smad and Akt/FoxO3 signaling pathways based on network pharmacology analysis.

Zhou Y, Wu R, Cai FF, Zhou WJ, Lu YY, Zhang H, Chen QL, Su SB
Journal of ethnopharmacology 2021 Jan 10;264:113021

Development of a novel anti-liver fibrosis formula with luteolin, licochalcone A, aloe-emodin and acacetin by network pharmacology and transcriptomics analysis.

Zhou Y, Wu R, Cai FF, Zhou WJ, Lu YY, Zhang H, Chen QL, Sun MY, Su SB
Pharmaceutical biology 2021 Dec;59(1):1594-1606

WTIP upregulates FOXO3a and induces apoptosis through PUMA in acute myeloid leukemia.

Zhu Y, Tong X, Wang Y, Lu X
Cell death & disease 2021 Dec 20;13(1):18

EGFR/FOXO3A/LXR-α Axis Promotes Prostate Cancer Proliferation and Metastasis and Dual-Targeting LXR-α/EGFR Shows Synthetic Lethality.

Chen T, Xu J, Fu W
Frontiers in oncology 2020;10:1688

TNNC1 Reduced Gemcitabine Sensitivity of Nonsmall-Cell Lung Cancer by Increasing Autophagy.

Ye X, Xie G, Liu Z, Tang J, Cui M, Wang C, Guo C, Tang J
Medical science monitor : international medical journal of experimental and clinical research 2020 Sep 18;26:e922703

MiR-23a-5p exacerbates intestinal ischemia-reperfusion injury by promoting oxidative stress via targeting PPAR alpha.

Li LX, Yin LH, Gao M, Xu LN, Qi Y, Peng JY
Biochemical pharmacology 2020 Oct;180:114194

Ascorbic acid enhances low-density lipoprotein receptor expression by suppressing proprotein convertase subtilisin/kexin 9 expression.

Wang D, Yang X, Chen Y, Gong K, Yu M, Gao Y, Wu X, Hu H, Liao C, Han J, Duan Y
The Journal of biological chemistry 2020 Nov 20;295(47):15870-15882

CDKL3 promotes osteosarcoma progression by activating Akt/PKB.

He A, Ma L, Huang Y, Zhang H, Duan W, Li Z, Fei T, Yuan J, Wu H, Liu L, Bai Y, Dai W, Wang Y, Li H, Sun Y, Wang Y, Wang C, Yuan T, Yang Q, Tian S, Dong M, Sheng R, Xiang D
Life science alliance 2020 May;3(5)

Linc00261 inhibits metastasis and the WNT signaling pathway of pancreatic cancer by regulating a miR‑552‑5p/FOXO3 axis.

Chen T, Lei S, Zeng Z, Zhang J, Xue Y, Sun Y, Lan J, Xu S, Mao D, Guo B
Oncology reports 2020 Mar;43(3):930-942

LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress.

Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, Liao C, Xie Z, Zhao B, Han J, Duan Y, Yang X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Mar;123:109803

Chlorzoxazone, a small molecule drug, augments immunosuppressive capacity of mesenchymal stem cells via modulation of FOXO3 phosphorylation.

Deng L, Li H, Su X, Zhang Y, Xu H, Fan L, Fan J, Han Q, Bai X, Zhao RC
Cell death & disease 2020 Mar 2;11(3):158

Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.

Yang S, Zhao N, Sun B, Yang Y, Hu Y, Zhao R
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494

Carfilzomib inhibits the growth of lung adenocarcinoma via upregulation of Gadd45a expression.

Yang F, Liu WW, Chen H, Zhu J, Huang AH, Zhou F, Gan Y, Zhang YH, Ma L
Journal of Zhejiang University. Science. B 2020 Jan.;21(1):64-76

FOXO3/TRIM22 axis abated the antitumor effect of gemcitabine in non-small cell lung cancer via autophagy induction.

Wang Y, Liang HX, Zhang CM, Zou M, Zou BB, Wei W, Hu W
Translational cancer research 2020 Feb;9(2):937-948

Exogenous CGRP Regulates Apoptosis and Autophagy to Alleviate Traumatic Brain Injury Through Akt/mTOR Signalling Pathway.

Tian J, Yang L, Wang P, Yang L, Fan Z
Neurochemical research 2020 Dec;45(12):2926-2938

Loss of high-temperature requirement protein A2 protease activity induces mitonuclear imbalance via differential regulation of mitochondrial biogenesis in sarcopenia.

Zhou H, Yuan D, Gao W, Tian J, Sun H, Yu S, Wang J, Sun L
IUBMB life 2020 Aug;72(8):1659-1679

FOXO3 protects nucleus pulposus cells against apoptosis under nutrient deficiency via autophagy.

Wang Y, Yang Y, Zuo R, Wu J, Zhang C, Li C, Liu M, Zhou Y
Biochemical and biophysical research communications 2020 Apr 9;524(3):756-763

BH3 mimetic ABT-263 enhances the anticancer effects of apigenin in tumor cells with activating EGFR mutation.

Zhan Y, Wang Y, Qi M, Liang P, Ma Y, Li T, Li H, Dai C, An Z, Qi Y, Wu H, Shao H
Cell & bioscience 2019;9:60

circRNA_0025202 Regulates Tamoxifen Sensitivity and Tumor Progression via Regulating the miR-182-5p/FOXO3a Axis in Breast Cancer.

Sang Y, Chen B, Song X, Li Y, Liang Y, Han D, Zhang N, Zhang H, Liu Y, Chen T, Li C, Wang L, Zhao W, Yang Q
Molecular therapy : the journal of the American Society of Gene Therapy 2019 Sep 4;27(9):1638-1652

Doxorubicin obliterates mouse ovarian reserve through both primordial follicle atresia and overactivation.

Wang Y, Liu M, Johnson SB, Yuan G, Arriba AK, Zubizarreta ME, Chatterjee S, Nagarkatti M, Nagarkatti P, Xiao S
Toxicology and applied pharmacology 2019 Oct 15;381:114714

Punicalagin Prevents Inflammation in LPS-Induced RAW264.7 Macrophages by Inhibiting FoxO3a/Autophagy Signaling Pathway.

Cao Y, Chen J, Ren G, Zhang Y, Tan X, Yang L
Nutrients 2019 Nov 15;11(11)

A New Possible Mechanism by Which Punicalagin Protects against Liver Injury Induced by Type 2 Diabetes Mellitus: Upregulation of Autophagy via the Akt/FoxO3a Signaling Pathway.

Zhang Y, Cao Y, Chen J, Qin H, Yang L
Journal of agricultural and food chemistry 2019 Dec 18;67(50):13948-13959

Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation.

Liu L, Chen H, Jin J, Tang Z, Yin P, Zhong D, Li G
Life sciences 2019 Dec 15;239:117036

Resveratrol induces apoptosis of benign prostatic hyperplasia epithelial cell line (BPH-1) through p38 MAPK-FOXO3a pathway.

Li C, Hu WL, Lu MX, Xiao GF
BMC complementary and alternative medicine 2019 Aug 29;19(1):233

Caffeine Protects Skin from Oxidative Stress-Induced Senescence through the Activation of Autophagy.

Li YF, Ouyang SH, Tu LF, Wang X, Yuan WL, Wang GE, Wu YP, Duan WJ, Yu HM, Fang ZZ, Kurihara H, Zhang Y, He RR
Theranostics 2018;8(20):5713-5730

Casticin prevents DSS induced ulcerative colitis in mice through inhibitions of NF-κB pathway and ROS signaling.

Ma J, Yin G, Lu Z, Xie P, Zhou H, Liu J, Yu L
Phytotherapy research : PTR 2018 Sep;32(9):1770-1783

Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.

Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713

Expression of PIM-1 in salivary gland adenoid cystic carcinoma: Association with tumor progression and patients' prognosis.

Zhu X, Yu Y, Hou X, Xu J, Tan Z, Nie X, Ling Z, Ge M
Oncology letters 2018 Jan;15(1):1149-1156

Nuclear forkhead box O3a accumulation contributing to the proliferative suppression in liver cancer cells by PI3K/Akt signaling pathway.

Hou Y, Sun G, Jiang X, Zhu Z, Yang J
Journal of cancer research and therapeutics 2018 Dec;14(Supplement):S1124-S1128

Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.

Zhang C, Li C, Chen S, Li Z, Ma L, Jia X, Wang K, Bao J, Liang Y, Chen M, Li P, Su H, Lee SM, Liu K, Wan JB, He C
Scientific reports 2017 Jan 23;7:41082

High glucose induces apoptosis via upregulation of Bim expression in proximal tubule epithelial cells.

Zhang XQ, Dong JJ, Cai T, Shen X, Zhou XJ, Liao L
Oncotarget 2017 Apr 11;8(15):24119-24129

Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.

Yang Y, Li X, Sun Q, He B, Jia Y, Cai D, Zhao R
The international journal of biochemistry & cell biology 2016 Oct;79:222-230

CHIP promotes thyroid cancer proliferation via activation of the MAPK and AKT pathways.

Zhang L, Liu L, He X, Shen Y, Liu X, Wei J, Yu F, Tian J
Biochemical and biophysical research communications 2016 Aug 26;477(3):356-62

Low-protein diet fed to crossbred sows during pregnancy and lactation enhances myostatin gene expression through epigenetic regulation in skeletal muscle of weaning piglets.

Jia Y, Gao G, Song H, Cai D, Yang X, Zhao R
European journal of nutrition 2016 Apr;55(3):1307-14

Rictor/mTORC2 pathway in oocytes regulates folliculogenesis, and its inactivation causes premature ovarian failure.

Chen Z, Kang X, Wang L, Dong H, Wang C, Xiong Z, Zhao W, Jia C, Lin J, Zhang W, Yuan W, Zhong M, Du H, Bai X
The Journal of biological chemistry 2015 Mar 6;290(10):6387-96

miRNA-155 modulates the malignant biological characteristics of NK/T-cell lymphoma cells by targeting FOXO3a gene.

Ji WG, Zhang XD, Sun XD, Wang XQ, Chang BP, Zhang MZ
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2014 Dec;34(6):882-888

No comments: Submit comment

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HEK-293 cells were subjected to SDS PAGE followed by western blot with 10849-1-AP(FOXO3A antibody) at dilution of 1:500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human breast cancer using 10849-1-AP(FOXO3A antibody) at dilution of 1:50 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The FOXO3A antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FOXO3A. This antibody recognizes human,mouse,rat antigen. The FOXO3A antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Appendix: 10849-1-AP.pdf

: Show more