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- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB5364 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB5364, RRID:AB_1574939
- Product name
- FOXO3 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of FOXO3.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease.
Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).
Hwang JW, Rajendrasozhan S, Yao H, Chung S, Sundar IK, Huyck HL, Pryhuber GS, Kinnula VL, Rahman I
Journal of immunology (Baltimore, Md. : 1950) 2011 Jul 15;187(2):987-98
Journal of immunology (Baltimore, Md. : 1950) 2011 Jul 15;187(2):987-98
Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.
Essafi A, Fernández de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS, Medema RH, Lam EW
Oncogene 2005 Mar 31;24(14):2317-29
Oncogene 2005 Mar 31;24(14):2317-29
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, Kusiak JW
The Journal of cell biology 2005 Apr 25;169(2):331-9
The Journal of cell biology 2005 Apr 25;169(2):331-9
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).
Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME
Molecular and cellular biology 2001 Feb;21(3):952-65
Molecular and cellular biology 2001 Feb;21(3):952-65
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of extract from NIH/3T3 using FOXO3 polyclonal antibody (Cat # PAB5364) .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using FOXO3 polyclonal antibody (Cat # PAB5364) .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
