Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- P00252 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-Phospho-FoxO3a (S253) Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for FKHRL1/FOXO3 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IHC, WB. Reactive species: Human, Mouse, Rat FKHRL1/FOXO3 information: Molecular Weight: 71277 MW; Subcellular Localization: Cytoplasm, cytosol. Nucleus. Translocates to the nucleus upon oxidative stress and in the absence of survival factors; Tissue Specificity: Ubiquitous.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- ECG-6
- Vial size
- 100ug/vial
- Concentration
- 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references (2E)-1-(2,4,6-Trimethoxyphenyl)-3-(4-chlorophenyl)prop-2-en-1-one, a Chalcone Derivative, Promotes Apoptosis by Suppressing RAS-ERK and AKT/FOXO3a Pathways in Hepatocellular Carcinoma Cells.
TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer's disease mice.
Fucoxanthin Alleviates Oxidative Stress through Akt/Sirt1/FoxO3α Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs.
Zhang M, Li J, Ma R, Xi J, Xi L, Zhang B, Tian J, Bai Z
Chemistry & biodiversity 2023 Jul;20(7):e202300050
Chemistry & biodiversity 2023 Jul;20(7):e202300050
TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer's disease mice.
Wang Y, Lin Y, Wang L, Zhan H, Luo X, Zeng Y, Wu W, Zhang X, Wang F
Aging 2020 Oct 16;12(20):20862-20879
Aging 2020 Oct 16;12(20):20862-20879
Fucoxanthin Alleviates Oxidative Stress through Akt/Sirt1/FoxO3α Signaling to Inhibit HG-Induced Renal Fibrosis in GMCs.
Yang G, Jin L, Zheng D, Tang X, Yang J, Fan L, Xie X
Marine drugs 2019 Dec 12;17(12)
Marine drugs 2019 Dec 12;17(12)
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Western blot analysis of Phospho-FoxO3a (S253) expression in MCF-7 cell lysate treated with IGF.
- Additional image