Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM02086G - Provider product page
- Provider
- Leading Biology
- Product name
- FOXO3 / FOXO3A Antibody (clone 2H2)
- Antibody type
- Monoclonal
- Description
- Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post- transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 2H2
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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