Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations [0]
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- Product number
- ABIN966150 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
- Antibody type
- Polyclonal
- Antigen
- The antiserum was produced against synthesized phosphopeptide derived from human FKHRL1 around the phosphorylation site of serine 253 (A-V-SP-M-D).
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pSer253
- Vial size
- 100 μg
- Concentration
- 100ug/100ul.
- Storage
- -20°C
Submitted references Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
Infectious vaginitis. Selecting therapy and preventing recurrence.
Essafi A, Fernández de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS, Medema RH, Lam EW
Oncogene 2005 Mar 31;24(14):2317-29
Oncogene 2005 Mar 31;24(14):2317-29
Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.
Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, Kusiak JW
The Journal of cell biology 2005 Apr 25;169(2):331-9
The Journal of cell biology 2005 Apr 25;169(2):331-9
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).
Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME
Molecular and cellular biology 2001 Feb;21(3):952-65
Molecular and cellular biology 2001 Feb;21(3):952-65
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME
Cell 1999 Mar 19;96(6):857-68
Cell 1999 Mar 19;96(6):857-68
Infectious vaginitis. Selecting therapy and preventing recurrence.
Goode MA, Grauer K, Gums JG
Postgraduate medicine 1994 Nov 1;96(6):85-8, 91-8
Postgraduate medicine 1994 Nov 1;96(6):85-8, 91-8
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