ABIN966151

antibody from antibodies-online

Targeting: FOXO3 AF6q21, FKHRL1, FOXO2, FOXO3A

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966151

Provider

antibodies-online

Product name

anti-Forkhead Box O3 (FOXO3) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR1 around the phosphorylation site of serine 253.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

Essafi A, Fernández de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS, Medema RH, Lam EW
Oncogene 2005 Mar 31;24(14):2317-29

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Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity.

Smith WW, Norton DD, Gorospe M, Jiang H, Nemoto S, Holbrook NJ, Finkel T, Kusiak JW
The Journal of cell biology 2005 Apr 25;169(2):331-9

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Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a).

Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME
Molecular and cellular biology 2001 Feb;21(3):952-65

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor.

Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME
Cell 1999 Mar 19;96(6):857-68

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Infectious vaginitis. Selecting therapy and preventing recurrence.

Goode MA, Grauer K, Gums JG
Postgraduate medicine 1994 Nov 1;96(6):85-8, 91-8