ABIN1355835

antibody from antibodies-online

Targeting: FOXO3 AF6q21, FKHRL1, FOXO2, FOXO3A

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN1355835

Provider

antibodies-online

Product name

anti-Forkhead Box O3 (FOXO3) (pSer253) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around phosphorylation site of pSer253 (A-V-S (p) -M-D) derived from Human FKHRL1. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

pSer253

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C

References

Submitted references

Over-expression of heat shock factor 1 phenocopies the effect of chronic inhibition of TOR by rapamycin and is sufficient to ameliorate Alzheimer's-like deficits in mice modeling the disease.

Pierce A, Podlutskaya N, Halloran JJ, Hussong SA, Lin PY, Burbank R, Hart MJ, Galvan V
Journal of neurochemistry 2013 Mar;124(6):880-93

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The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis.

Kress TR, Cannell IG, Brenkman AB, Samans B, Gaestel M, Roepman P, Burgering BM, Bushell M, Rosenwald A, Eilers M
Molecular cell 2011 Feb 18;41(4):445-57

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Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre-conditioning in adult rats.

Zhan L, Wang T, Li W, Xu ZC, Sun W, Xu E
Journal of neurochemistry 2010 Aug;114(3):897-908

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Pim kinases promote cell cycle progression by phosphorylating and down-regulating p27Kip1 at the transcriptional and posttranscriptional levels.

Morishita D, Katayama R, Sekimizu K, Tsuruo T, Fujita N
Cancer research 2008 Jul 1;68(13):5076-85