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- References [163]
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- Product number
- 22034-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PTEN antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PTEN antibody (Cat. #22034-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Radix Bupleuri-Radix Paeoniae Alba Inhibits the Development of Hepatocellular Carcinoma through Activation of the PTEN/PD-L1 Axis within the Immune Microenvironment.
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
Extracellular vesicle-encapsulated miR-25-3p promotes epithelial-mesenchymal transition and migration of endometrial epithelial cells by inducing macrophage polarization.
SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis.
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
PTEN Mediates the Silencing of Unintegrated HIV-1 DNA.
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.
MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway.
Identification of a circulating three-miRNA panel for the diagnosis of primary open angle glaucoma.
Network Pharmacology and Experimental Validation to Explore That Celastrol Targeting PTEN is the Potential Mechanism of Tripterygium wilfordii (Lév.) Hutch Against IgA Nephropathy.
Molecular mechanism of miRNA-23a in sepsis-induced lung injury.
PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN.
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation.
The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression.
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Inhibition of checkpoint kinase prevents human oocyte apoptosis induced by chemotherapy and allows enhanced tumour chemotherapeutic efficacy.
Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset.
Dietary neoagarotetraose extends lifespan and impedes brain aging in mice via regulation of microbiota-gut-brain axis.
Hsa_circ_0001535 inhibits the proliferation and migration of ovarian cancer by sponging miR-593-3p, upregulating PTEN expression.
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Targeting PI3Kα increases the efficacy of anti-PD-1 antibody in cervical cancer.
Colorectal cancer tumor cell-derived exosomal miR-203a-3p promotes CRC metastasis by targeting PTEN-induced macrophage polarization.
IL1RAP Knockdown in LPS-Stimulated Normal Human Astrocytes Suppresses LPS-Induced Reactive Astrogliosis and Promotes Neuronal Cell Proliferation.
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
CircNDST1 promotes papillary thyroid cancer progression via its interaction with CSNK2A1 to activate the PI3K-Akt pathway and epithelial-mesenchymal transition.
Preoperative fibrinogen is associated with the clinical survival of primary liver cancer patients and promotes hepatoma metastasis via the PTEN/AKT/mTOR pathway.
Effect of isorhamnetin on carbonic anhydrase IX expression and tumorigenesis of bladder cancer by activating PPARγ/PTEN/AKT pathway.
LINC00493-encoded microprotein SMIM26 exerts anti-metastatic activity in renal cell carcinoma.
YTHDC1 positively regulates PTEN expression and plays a critical role in cisplatin resistance of bladder cancer.
Triptolide alleviates collagen-induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN-STAT3 pathway.
Mesenchymal stem cells, as glioma exosomal immunosuppressive signal multipliers, enhance MDSCs immunosuppressive activity through the miR-21/SP1/DNMT1 positive feedback loop.
[MiR-30e-5p overexpression promotes proliferation and migration of colorectal cancer cells by activating the CXCL12 axis via downregulating PTEN].
Geraniol prevents Helicobacterium pylori-induced human gastric cancer signalling by enhancing peroxiredoxin-1 expression in GES-1 cells.
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
Digital color-coded molecular barcoding reveals dysregulation of common FUS and FMRP targets in soma and neurites of ALS mutant motoneurons.
High dose isoleucine stabilizes nuclear PTEN to suppress the proliferation of lung cancer.
Schwann Cell-Derived Exosomes Ameliorate Paclitaxel-Induced Peripheral Neuropathy Through the miR-21-Mediated PTEN Signaling Pathway.
Exosomes derived from bone marrow mesenchymal stem cells pretreated with decellularized extracellular matrix enhance the alleviation of osteoarthritis through miR-3473b/phosphatase and tensin homolog axis.
CHMP4A stimulates CD8+ T-lymphocyte infiltration and inhibits breast tumor growth via the LSD1/IFNβ axis.
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
Extracellular vesicles contribute to EMT in adenomyosis by inducing macrophage polarization†.
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs.
Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression.
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Calycosin suppresses colorectal cancer progression by targeting ERβ, upregulating PTEN, and inhibiting PI3K/Akt signal pathway.
E2F1/CKS2/PTEN signaling axis regulates malignant phenotypes in pediatric retinoblastoma.
circRNF10 Regulates Tumorigenic Properties and Natural Killer Cell-Mediated Cytotoxicity against Breast Cancer through the miR-934/PTEN/PI3k-Akt Axis.
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.
USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression.
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma.
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN.
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Maf1 regulates axonal regeneration of retinal ganglion cells after injury.
Metformin and MiR-365 synergistically promote the apoptosis of gastric cancer cells via MiR-365-PTEN-AMPK axis.
The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma.
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Molecular profiling identifies distinct subtypes across TP53 mutant tumors.
High yield engineered nanovesicles from ADSC with enriched miR-21-5p promote angiogenesis in adipose tissue regeneration.
A WWP2-PTEN-KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice.
Growth arrest-specific transcript 5 represses endometrial cancer development by promoting antitumor function of tumor-associated macrophages.
Identification of distinct genomic features reveals frequent somatic AHNAK and PTEN mutations predominantly in primary malignant melanoma presenting in the ureter.
METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m(6)A-YTHDF2-dependent manner.
S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.
Circular RNA BIRC6 depletion promotes osteogenic differentiation of periodontal ligament stem cells via the miR-543/PTEN/PI3K/AKT/mTOR signaling pathway in the inflammatory microenvironment.
miR-141-3p regulates saturated fatty acid-induced cardiomyocyte apoptosis through Notch1/PTEN/AKT pathway via targeting PSEN1.
miR-AB, a miRNA-based shRNA viral toolkit for multicolor-barcoded multiplex RNAi at a single-cell level.
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway.
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy.
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
miR-4461 Regulates the Proliferation and Metastasis of Ovarian Cancer Cells and Cisplatin Resistance.
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
miR-638 suppresses proliferation by negatively regulating high mobility group A1 in ovarian cancer cells.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
DEHP-elicited small extracellular vesicles miR-26a-5p promoted metastasis in nearby normal A549 cells.
Improvement of hyperlipidemia by aerobic exercise in mice through a regulatory effect of miR-21a-5p on its target genes.
Ginsenoside Rh2 alleviates ulcerative colitis by regulating the STAT3/miR-214 signaling pathway.
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism.
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
Circular RNA circRAB31 acts as a miR-885-5psponge to suppress gastric cancer progressionvia the PTEN/PI3K/AKT pathway.
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Exosome-Delivered LncHEIH Promotes Gastric Cancer Progression by Upregulating EZH2 and Stimulating Methylation of the GSDME Promoter.
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Lapatinib‑induced inhibition of ovarian function is counteracted by the STAT3 pathway both in vivo and in vitro.
Targeting DNA to the endoplasmic reticulum efficiently enhances gene delivery and therapy.
SET8 suppression mediates high glucose-induced vascular endothelial inflammation via the upregulation of PTEN.
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
KIF15 contributes to cell proliferation and migration in breast cancer.
HOTAIR maintains the stemness of ovarian cancer stem cells via the miR-206/TBX3 axis.
Lamin B1 deficiency promotes malignancy and predicts poor prognosis in gastric cancer.
MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer.
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
Neuroprotective effects of miR-532-5p against ischemic stroke.
ChREBP-β regulates thermogenesis in brown adipose tissue.
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
LukS-PV Inhibits Hepatocellular Carcinoma Progression by Downregulating HDAC2 Expression.
Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro.
Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling.
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury.
Alginate oligosaccharide protects endothelial cells against oxidative stress injury via integrin-α/FAK/PI3K signaling.
LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
Long non-coding RNA MAGI2-AS3 inhibits breast cancer cell migration and invasion via sponging microRNA-374a.
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b.
Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin.
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway.
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Down-regulation of miR-543 expression increases the sensitivity of colorectal cancer cells to 5-Fluorouracil through the PTEN/PI3K/AKT pathway.
Long noncoding RNA DGCR5 suppresses gastric cancer progression by acting as a competing endogenous RNA of PTEN and BTG1.
Evaluation of differentially expressed microRNAs in vitrified oocytes by next generation sequencing.
Triptolide impairs thioredoxin system by suppressing Notch1-mediated PTEN/Akt/Txnip signaling in hepatocytes.
Calpain2 but not calpain1 mediated by calpastatin following glutamate-induced regulated necrosis in rat retinal neurons.
YY1-regulated LINC00152 promotes triple negative breast cancer progression by affecting on stability of PTEN protein.
Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma.
Morin Inhibits Proliferation and Induces Apoptosis by Modulating the miR-188-5p/PTEN/AKT Regulatory Pathway in CML Cells.
A panel of serum exosomal microRNAs as predictive markers for chemoresistance in advanced colorectal cancer.
Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma.
MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN.
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Proscillaridin A induces apoptosis, inhibits STAT3 activation and augments doxorubicin toxicity in prostate cancer cells.
miR-217 Promotes Cardiac Hypertrophy and Dysfunction by Targeting PTEN.
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
LASP1 promotes nasopharyngeal carcinoma progression through negatively regulation of the tumor suppressor PTEN.
Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN.
Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.
Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition.
Identification of differential gene expression profile from peripheral blood cells of military pilots with hypertension by RNA sequencing analysis.
Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib.
Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma.
MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer.
The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice.
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway.
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
FOXP1 forkhead transcription factor is associated with the pathogenesis of endometrial cancer.
Combination of microRNA-21 and microRNA-146a Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction in Mice.
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Paper-based microreactor array for rapid screening of cell signaling cascades.
Modeling glands with PTEN deficient cells and microscopic methods for assessing PTEN loss: endometrial cancer as a model.
Best practice for PTEN gene and protein assessment in anatomic pathology.
miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer.
Zhang F, Zhou K, Yuan W, Sun K
Nutrition and cancer 2024;76(1):63-79
Nutrition and cancer 2024;76(1):63-79
β-Sitosterol targets ASS1 for Nrf2 ubiquitin-dependent degradation, inducing ROS-mediated apoptosis via the PTEN/PI3K/AKT signaling pathway in ovarian cancer.
Wang H, Liu J, Zhang Z, Peng J, Wang Z, Yang L, Wang X, Hu S, Hong L
Free radical biology & medicine 2024 Mar;214:137-157
Free radical biology & medicine 2024 Mar;214:137-157
Extracellular vesicle-encapsulated miR-25-3p promotes epithelial-mesenchymal transition and migration of endometrial epithelial cells by inducing macrophage polarization.
Hu Y, Yuan M, Cheng L, Xu L, Wang G
Molecular human reproduction 2024 Mar 28;30(4)
Molecular human reproduction 2024 Mar 28;30(4)
SNHG4-mediated PTEN destabilization confers oxaliplatin resistance in colorectal cancer cells by inhibiting ferroptosis.
Li SQ, Xu WT, Yin YX, Wei HT, Li KZ, Xie MZ, Lv F, Xie LY, Hu BL
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):835-848
Apoptosis : an international journal on programmed cell death 2024 Jun;29(5-6):835-848
TC2N inhibits distant metastasis and stemness of breast cancer via blocking fatty acid synthesis.
Hao XL, Lv YF, Li DF, Bai FH, Gong J, Pan GQ, Su LX, Wang YL, Fu WL, Liu B, Huang L, Yan D, Tan QL, Liu JY, Guo QN
Journal of translational medicine 2024 Jan 2;22(1):6
Journal of translational medicine 2024 Jan 2;22(1):6
Tumor-associated macrophage-derived exosomal miR-513b-5p is a target of jianpi yangzheng decoction for inhibiting gastric cancer.
Zhang R, Chen X, Miao C, Chen Y, Li Y, Shen J, Yuan M, Chen M, Cheng J, Liu S, Sun Q, Wu J
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117013
PTEN Mediates the Silencing of Unintegrated HIV-1 DNA.
Phan AT, Zhu Y
Viruses 2024 Feb 14;16(2)
Viruses 2024 Feb 14;16(2)
Down-expression of miR-494-3p in senescent osteocyte-derived exosomes inhibits osteogenesis and accelerates age-related bone loss via PTEN/PI3K/AKT pathway.
Yao C, Sun J, Luo W, Chen H, Chen T, Chen C, Zhang B, Zhang Y
Bone & joint research 2024 Feb 1;13(2):52-65
Bone & joint research 2024 Feb 1;13(2):52-65
MATN2 overexpression suppresses tumor growth in ovarian cancer via PTEN/PI3K/AKT pathway.
Liu J, Zhang J, Zhang Y, Yang B, Liu H, Chen Y
Functional & integrative genomics 2024 Apr 3;24(2):71
Functional & integrative genomics 2024 Apr 3;24(2):71
Identification of a circulating three-miRNA panel for the diagnosis of primary open angle glaucoma.
Qin B, Li LP, Xu QD, Lei Y, Chen YH
International ophthalmology 2024 Apr 15;44(1):176
International ophthalmology 2024 Apr 15;44(1):176
Network Pharmacology and Experimental Validation to Explore That Celastrol Targeting PTEN is the Potential Mechanism of Tripterygium wilfordii (Lév.) Hutch Against IgA Nephropathy.
Zhao J, Liu H, Xia M, Chen Q, Wan L, Leng B, Tang C, Chen G, Liu Y, Zhang L, Liu H
Drug design, development and therapy 2023;17:887-900
Drug design, development and therapy 2023;17:887-900
Molecular mechanism of miRNA-23a in sepsis-induced lung injury.
Zhang P, Huang Q, Liao P, Sun S, Yang J
American journal of translational research 2023;15(6):3900-3911
American journal of translational research 2023;15(6):3900-3911
PRMT7 Inhibits the Proliferation and Migration of Gastric Cancer Cells by Suppressing the PI3K/AKT Pathway via PTEN.
Wang X, Xu W, Zhu C, Cheng Y, Qi J
Journal of Cancer 2023;14(15):2833-2844
Journal of Cancer 2023;14(15):2833-2844
S-Nitrosylation-mediated coupling of DJ-1 with PTEN induces PI3K/AKT/mTOR pathway-dependent keloid formation.
Lv D, Xu Z, Cheng P, Hu Z, Dong Y, Rong Y, Xu H, Wang Z, Cao X, Deng W, Tang B
Burns & trauma 2023;11:tkad024
Burns & trauma 2023;11:tkad024
The m6A reader YTHDC1-mediated lncRNA CTBP1-AS2 m6A modification accelerates cholangiocarcinoma progression.
Jin Z, Liu Y
Heliyon 2023 Sep;9(9):e19816
Heliyon 2023 Sep;9(9):e19816
Targeting Squalene Epoxidase Confers Metabolic Vulnerability and Overcomes Chemoresistance in HNSCC.
Zhao X, Guo B, Sun W, Yu J, Cui L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(27):e2206878
Inhibition of checkpoint kinase prevents human oocyte apoptosis induced by chemotherapy and allows enhanced tumour chemotherapeutic efficacy.
Wu M, Xue L, Chen Y, Tang W, Guo Y, Xiong J, Chen D, Zhu Q, Fu F, Wang S
Human reproduction (Oxford, England) 2023 Sep 5;38(9):1769-1783
Human reproduction (Oxford, England) 2023 Sep 5;38(9):1769-1783
Myo9b mutations are associated with altered dendritic cell functions and increased susceptibility to autoimmune diabetes onset.
Zhang J, Zou Y, Chen L, Sun F, Xu Q, Zhou Q, Wang Y, Luo X, Wang N, Li Y, Zhang S, Xiong F, Yang P, Liu S, Yang T, Weng J, Eizirik DL, Yan J, Zhou Z, Wang CY
Nature communications 2023 Sep 25;14(1):5977
Nature communications 2023 Sep 25;14(1):5977
Dietary neoagarotetraose extends lifespan and impedes brain aging in mice via regulation of microbiota-gut-brain axis.
Li T, Yang S, Liu X, Li Y, Gu Z, Jiang Z
Journal of advanced research 2023 Oct;52:119-134
Journal of advanced research 2023 Oct;52:119-134
Hsa_circ_0001535 inhibits the proliferation and migration of ovarian cancer by sponging miR-593-3p, upregulating PTEN expression.
Han Y, Zheng Y, You J, Han Y, Lu X, Wang X, Shi C, Zhu W
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):2901-2910
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2023 Oct;25(10):2901-2910
Streptococcus uberis induced expressions of pro-inflammatory IL-6, TNF-α, and IFN-γ in bovine mammary epithelial cells associated with inhibited autophagy and autophagy flux formation.
Khan S, Yang J, Cobo ER, Wang Y, Xu M, Wang T, Shi Y, Liu G, Han B
Microbial pathogenesis 2023 Oct;183:106270
Microbial pathogenesis 2023 Oct;183:106270
Targeting PI3Kα increases the efficacy of anti-PD-1 antibody in cervical cancer.
Jiang W, Ouyang X, Li C, Long Y, Chen W, Ji Z, Shen X, Xiang L, Yang H
Immunology 2023 Nov;170(3):419-438
Immunology 2023 Nov;170(3):419-438
Colorectal cancer tumor cell-derived exosomal miR-203a-3p promotes CRC metastasis by targeting PTEN-induced macrophage polarization.
Pei W, Wei K, Wu Y, Qiu Q, Zhu H, Mao L, Shi X, Zhang S, Shi Y, Tao S, Mao H, Pang S, Wang J, Liu M, Wang W, Yang Q, Chen C
Gene 2023 Nov 15;885:147692
Gene 2023 Nov 15;885:147692
IL1RAP Knockdown in LPS-Stimulated Normal Human Astrocytes Suppresses LPS-Induced Reactive Astrogliosis and Promotes Neuronal Cell Proliferation.
Zhou J, Xiang W, Zhang K, Zhao Q, Xu Z, Li Z
Neurochemical research 2023 May;48(5):1468-1479
Neurochemical research 2023 May;48(5):1468-1479
Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway.
Sun X, Huang LY, Pan HX, Li LJ, Wang L, Pei GQ, Wang Y, Zhang Q, Cheng HX, He CQ, Wei Q
Neural regeneration research 2023 May;18(5):1067-1075
Neural regeneration research 2023 May;18(5):1067-1075
β-Hydroxybutyrate alleviates cartilage senescence through hnRNP A1-mediated up-regulation of PTEN.
Xia G, Wen Z, Zhang L, Huang J, Wang X, Liang C, Cui X, Cao X, Wu S
Experimental gerontology 2023 May;175:112140
Experimental gerontology 2023 May;175:112140
RSL1D1 knockdown induces ferroptosis and mediates ferrous iron accumulation in senescent cells by inhibiting FTH1 mRNA stability.
Jin Y, Zhao L, Wang S, Zhang X, Quan J, Lin Z, Piao J
Carcinogenesis 2023 May 26;44(2):129-142
Carcinogenesis 2023 May 26;44(2):129-142
CircNDST1 promotes papillary thyroid cancer progression via its interaction with CSNK2A1 to activate the PI3K-Akt pathway and epithelial-mesenchymal transition.
Shu C, Wang S, Hu J, Xu M, Deng H, Maimaiti Y, Huang T
Journal of endocrinological investigation 2023 Mar;46(3):545-557
Journal of endocrinological investigation 2023 Mar;46(3):545-557
Preoperative fibrinogen is associated with the clinical survival of primary liver cancer patients and promotes hepatoma metastasis via the PTEN/AKT/mTOR pathway.
Qian X, Cai J, Qi Q, Han J, Zhu X, Xia R, Zhang Q
Heliyon 2023 Jun;9(6):e16696
Heliyon 2023 Jun;9(6):e16696
Effect of isorhamnetin on carbonic anhydrase IX expression and tumorigenesis of bladder cancer by activating PPARγ/PTEN/AKT pathway.
Zhang P, Sun Y, Shi L, Sun D, Wang L, Feng D, Ding C
Tissue & cell 2023 Jun;82:102048
Tissue & cell 2023 Jun;82:102048
LINC00493-encoded microprotein SMIM26 exerts anti-metastatic activity in renal cell carcinoma.
Meng K, Lu S, Li YY, Hu LL, Zhang J, Cao Y, Wang Y, Zhang CZ, He QY
EMBO reports 2023 Jun 5;24(6):e56282
EMBO reports 2023 Jun 5;24(6):e56282
YTHDC1 positively regulates PTEN expression and plays a critical role in cisplatin resistance of bladder cancer.
Su Y, Wang B, Huang J, Huang M, Lin T
Cell proliferation 2023 Jul;56(7):e13404
Cell proliferation 2023 Jul;56(7):e13404
Triptolide alleviates collagen-induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN-STAT3 pathway.
Huang Y, Ba X, Wang H, Shen P, Han L, Lin W, Yan J, Chen Z, Tu S
Basic & clinical pharmacology & toxicology 2023 Jul;133(1):43-58
Basic & clinical pharmacology & toxicology 2023 Jul;133(1):43-58
Mesenchymal stem cells, as glioma exosomal immunosuppressive signal multipliers, enhance MDSCs immunosuppressive activity through the miR-21/SP1/DNMT1 positive feedback loop.
Qiu W, Guo Q, Guo X, Wang C, Li B, Qi Y, Wang S, Zhao R, Han X, Du H, Zhao S, Pan Z, Fan Y, Wang Q, Gao Z, Li G, Xue H
Journal of nanobiotechnology 2023 Jul 22;21(1):233
Journal of nanobiotechnology 2023 Jul 22;21(1):233
[MiR-30e-5p overexpression promotes proliferation and migration of colorectal cancer cells by activating the CXCL12 axis via downregulating PTEN].
Wei K, Shi J, Xiao Y, Wang W, Yang Q, Chen C
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jul 20;43(7):1081-1092
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2023 Jul 20;43(7):1081-1092
Geraniol prevents Helicobacterium pylori-induced human gastric cancer signalling by enhancing peroxiredoxin-1 expression in GES-1 cells.
Zhuang K, Tang H, Guo H, Yuan S
Microbial pathogenesis 2023 Jan;174:105937
Microbial pathogenesis 2023 Jan;174:105937
The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region.
Fan G, Wang F, Chen Y, Zheng Q, Xiong J, Lv Q, Wu K, Xiong J, Wei L, Li D, Zhang J, Zhang W, Li F
Cell reports 2023 Jan 31;42(1):111916
Cell reports 2023 Jan 31;42(1):111916
Digital color-coded molecular barcoding reveals dysregulation of common FUS and FMRP targets in soma and neurites of ALS mutant motoneurons.
Garone MG, Salerno D, Rosa A
Cell death discovery 2023 Jan 26;9(1):33
Cell death discovery 2023 Jan 26;9(1):33
High dose isoleucine stabilizes nuclear PTEN to suppress the proliferation of lung cancer.
Wang H, Chen S, Kang W, Ding B, Cui S, Zhou L, Zhang N, Luo H, Wang M, Zhang F, Zhao Z, Guo Z, Wang C, Li L, Wang Z, Chen X, Wang Y
Discover oncology 2023 Feb 23;14(1):25
Discover oncology 2023 Feb 23;14(1):25
Schwann Cell-Derived Exosomes Ameliorate Paclitaxel-Induced Peripheral Neuropathy Through the miR-21-Mediated PTEN Signaling Pathway.
You M, Xing H, Yan M, Zhang J, Chen J, Chen Y, Liu X, Zhu J
Molecular neurobiology 2023 Dec;60(12):6840-6851
Molecular neurobiology 2023 Dec;60(12):6840-6851
Exosomes derived from bone marrow mesenchymal stem cells pretreated with decellularized extracellular matrix enhance the alleviation of osteoarthritis through miR-3473b/phosphatase and tensin homolog axis.
Zhang Y, Qi G, Yan Y, Wang C, Wang Z, Jiang C, Jiang Z, Ma T, Zhang C, Yan Z
The journal of gene medicine 2023 Aug;25(8):e3510
The journal of gene medicine 2023 Aug;25(8):e3510
CHMP4A stimulates CD8+ T-lymphocyte infiltration and inhibits breast tumor growth via the LSD1/IFNβ axis.
Song S, Zhang D, Chen J, Qi L, Zhang M, Yang X, Ye T, Ye Q, Lin J
Cancer science 2023 Aug;114(8):3162-3175
Cancer science 2023 Aug;114(8):3162-3175
Melatonin increases susceptibility to atrial fibrillation in obesity via Akt signaling impairment in response to lipid overload.
Qin X, Fu Y, Fan J, Liu B, Liu P, Zhang Y, Jiang T, Zheng Q
Journal of pineal research 2023 Apr;74(3):e12851
Journal of pineal research 2023 Apr;74(3):e12851
Extracellular vesicles contribute to EMT in adenomyosis by inducing macrophage polarization†.
Hu Y, Yuan M, Cheng L, Wang G
Biology of reproduction 2023 Apr 11;108(4):584-596
Biology of reproduction 2023 Apr 11;108(4):584-596
Astragaloside IV - mediated endothelial progenitor cell exosomes promote autophagy and inhibit apoptosis in hyperglycemic damaged endothelial cells via miR-21/PTEN axis.
Xiong W, Huang XL, Li CY, Wang XL, Lan HW, Wang TT, Chen ZL, Yang QP, Hu AL, Xia YF, Zhu FR, Zhou ZZ
Folia histochemica et cytobiologica 2022;60(4):323-334
Folia histochemica et cytobiologica 2022;60(4):323-334
OTUD1 stabilizes PTEN to inhibit the PI3K/AKT and TNF-alpha/NF-kappaB signaling pathways and sensitize ccRCC to TKIs.
Liu W, Yan B, Yu H, Ren J, Peng M, Zhu L, Wang Y, Jin X, Yi L
International journal of biological sciences 2022;18(4):1401-1414
International journal of biological sciences 2022;18(4):1401-1414
Targeting the chemerin/CMKLR1 axis by small molecule antagonist α-NETA mitigates endometriosis progression.
Yu M, Yang Y, Zhao H, Li M, Chen J, Wang B, Xiao T, Huang C, Zhao H, Zhou W, Zhang JV
Frontiers in pharmacology 2022;13:985618
Frontiers in pharmacology 2022;13:985618
Mycoplasma bovis inhibits autophagy in bovine mammary epithelial cells via a PTEN/PI3K-Akt-mTOR-dependent pathway.
Xu M, Liu Y, Mayinuer T, Lin Y, Wang Y, Gao J, Wang D, Kastelic JP, Han B
Frontiers in microbiology 2022;13:935547
Frontiers in microbiology 2022;13:935547
Calycosin suppresses colorectal cancer progression by targeting ERβ, upregulating PTEN, and inhibiting PI3K/Akt signal pathway.
Zhu L, Liu S, Liao YF, Sheng YM, He JC, Cai ZX, Man Q, Wu YY
Cell biology international 2022 Sep;46(9):1367-1377
Cell biology international 2022 Sep;46(9):1367-1377
E2F1/CKS2/PTEN signaling axis regulates malignant phenotypes in pediatric retinoblastoma.
Chen M, Zhao Z, Wu L, Huang J, Yu P, Qian J, Ni T, Zhao C
Cell death & disease 2022 Sep 12;13(9):784
Cell death & disease 2022 Sep 12;13(9):784
circRNF10 Regulates Tumorigenic Properties and Natural Killer Cell-Mediated Cytotoxicity against Breast Cancer through the miR-934/PTEN/PI3k-Akt Axis.
Liu F, Sang Y, Zheng Y, Gu L, Meng L, Li Z, Dong Y, Wei Z, Geng C, Sang M
Cancers 2022 Nov 28;14(23)
Cancers 2022 Nov 28;14(23)
MicroRNA-20a promotes non-small cell lung cancer proliferation by upregulating PD-L1 by targeting PTEN.
Gong J, Shen Y, Jiang F, Wang Y, Chu L, Sun J, Shen P, Chen M
Oncology letters 2022 May;23(5):148
Oncology letters 2022 May;23(5):148
Transformer 2 alpha homolog is a downstream gene of hypoxia-inducible factor 1 subunit alpha and is involved in the progression of pancreatic cancer.
Cao W, Lei S, Zeng Z, Xiao C, Sun B, Xie P, Li Y, Luo D, Yu W
Bioengineered 2022 May;13(5):13238-13251
Bioengineered 2022 May;13(5):13238-13251
USP22-mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression.
Ren D, Sun Y, Li D, Wu H, Jin X
Molecular oncology 2022 Mar;16(5):1200-1217
Molecular oncology 2022 Mar;16(5):1200-1217
PI3K inhibitor impairs tumor progression and enhances sensitivity to anlotinib in anlotinib-resistant osteosarcoma.
Chen C, Guo Y, Huang Q, Wang B, Wang W, Niu J, Lou J, Xu J, Ren T, Huang Y, Guo W
Cancer letters 2022 Jun 28;536:215660
Cancer letters 2022 Jun 28;536:215660
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN.
Zhang R, Ai J, Wang J, Sun C, Lu H, He A, Li M, Liao Y, Lei J, Zhou F, Wu L, Liao W
Journal of translational medicine 2022 Jul 21;20(1):325
Journal of translational medicine 2022 Jul 21;20(1):325
A novel FBW7/NFAT1 axis regulates cancer immunity in sunitinib-resistant renal cancer by inducing PD-L1 expression.
Liu W, Ren D, Xiong W, Jin X, Zhu L
Journal of experimental & clinical cancer research : CR 2022 Jan 26;41(1):38
Journal of experimental & clinical cancer research : CR 2022 Jan 26;41(1):38
Maf1 regulates axonal regeneration of retinal ganglion cells after injury.
Chen D, Sun YY, Zhou LY, Yang S, Hong FY, Liu XD, Sun ZL, Huang J, Feng DF
Experimental neurology 2022 Feb;348:113948
Experimental neurology 2022 Feb;348:113948
Metformin and MiR-365 synergistically promote the apoptosis of gastric cancer cells via MiR-365-PTEN-AMPK axis.
Huang F, Xiang Y, Li T, Huang Y, Wang J, Zhang HM, Li HH, Dai ZT, Li JP, Li H, Zhou J, Liao XH
Pathology, research and practice 2022 Feb;230:153740
Pathology, research and practice 2022 Feb;230:153740
The synergistic anticancer effect of the bromodomain inhibitor OTX015 and histone deacetylase 6 inhibitor WT-161 in osteosarcoma.
Yu B, Liu L, Cai F, Peng Y, Tang X, Zeng D, Li T, Zhang F, Liang Y, Yuan X, Li J, Dai Z, Liao Q, Lv XB
Cancer cell international 2022 Feb 8;22(1):64
Cancer cell international 2022 Feb 8;22(1):64
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Qin J, Sun X, Ma Y, Cheng Y, Ma Q, Jing W, Qu S, Liu L
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Molecular profiling identifies distinct subtypes across TP53 mutant tumors.
Chen X, Liu T, Wu J, Zhu C, Guan G, Zou C, Guo Q, Ren X, Li C, Cheng P, Cheng W, Wu A
JCI insight 2022 Dec 8;7(23)
JCI insight 2022 Dec 8;7(23)
High yield engineered nanovesicles from ADSC with enriched miR-21-5p promote angiogenesis in adipose tissue regeneration.
Sun D, Mou S, Chen L, Yang J, Wang R, Zhong A, Wang W, Tong J, Wang Z, Sun J
Biomaterials research 2022 Dec 17;26(1):83
Biomaterials research 2022 Dec 17;26(1):83
A WWP2-PTEN-KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice.
Fu J, Zhang X, Zheng H, Yang G, Chen Z, Yuan G
The Journal of biological chemistry 2022 Aug;298(8):102220
The Journal of biological chemistry 2022 Aug;298(8):102220
Growth arrest-specific transcript 5 represses endometrial cancer development by promoting antitumor function of tumor-associated macrophages.
Tu J, Tan X, Chen Y, Chen Y, Li Z, Zhang Y, Chen X, Yang H, Chen H, Yu Z
Cancer science 2022 Aug;113(8):2496-2512
Cancer science 2022 Aug;113(8):2496-2512
Identification of distinct genomic features reveals frequent somatic AHNAK and PTEN mutations predominantly in primary malignant melanoma presenting in the ureter.
Huang Y, Wei L, Huang Y, Wen S, Liu T, Duan X, Wang Y, Zhang H, Fan B, Hu B
Japanese journal of clinical oncology 2022 Aug 5;52(8):930-943
Japanese journal of clinical oncology 2022 Aug 5;52(8):930-943
METTL3 promotes prostatic hyperplasia by regulating PTEN expression in an m(6)A-YTHDF2-dependent manner.
Li J, Yao H, Huang J, Li C, Zhang Y, Xu R, Wang Z, Long Z, Tang J, Wang L
Cell death & disease 2022 Aug 19;13(8):723
Cell death & disease 2022 Aug 19;13(8):723
S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway.
Sun Y, Zhang H, Meng J, Guo F, Ren D, Wu H, Jin X
Cell reports 2022 Aug 16;40(7):111194
Cell reports 2022 Aug 16;40(7):111194
Circular RNA BIRC6 depletion promotes osteogenic differentiation of periodontal ligament stem cells via the miR-543/PTEN/PI3K/AKT/mTOR signaling pathway in the inflammatory microenvironment.
Zhao X, Sun W, Guo B, Cui L
Stem cell research & therapy 2022 Aug 13;13(1):417
Stem cell research & therapy 2022 Aug 13;13(1):417
miR-141-3p regulates saturated fatty acid-induced cardiomyocyte apoptosis through Notch1/PTEN/AKT pathway via targeting PSEN1.
Xin X, Duan L, Yang H, Yu H, Bao Y, Jia D, Wu N, Qiao Y
Environmental toxicology 2022 Apr;37(4):741-753
Environmental toxicology 2022 Apr;37(4):741-753
miR-AB, a miRNA-based shRNA viral toolkit for multicolor-barcoded multiplex RNAi at a single-cell level.
Wang D, Xiu J, Zhao J, Luo J
EMBO reports 2022 Apr 5;23(4):e53691
EMBO reports 2022 Apr 5;23(4):e53691
Brusatol inhibits the growth of renal cell carcinoma by regulating the PTEN/PI3K/AKT pathway.
Wang T, Chen Z, Chen H, Yu X, Wang L, Liu X
Journal of ethnopharmacology 2022 Apr 24;288:115020
Journal of ethnopharmacology 2022 Apr 24;288:115020
Evodiamine Inhibits Gastric Cancer Cell Proliferation via PTEN-Mediated EGF/PI3K Signaling Pathway.
Yang R, Wen J, Yang T, Dai C, Zhao Y
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5570831
Evidence-based complementary and alternative medicine : eCAM 2021;2021:5570831
Downregulation of miR‑214-3p attenuates mesangial hypercellularity by targeting PTEN‑mediated JNK/c-Jun signaling in IgA nephropathy.
Li Y, Xia M, Peng L, Liu H, Chen G, Wang C, Yuan D, Liu Y, Liu H
International journal of biological sciences 2021;17(13):3343-3355
International journal of biological sciences 2021;17(13):3343-3355
Pentamidine Inhibits Ovarian Cancer Cell Proliferation and Migration by Maintaining Stability of PTEN in vitro.
Wu Y, Zhang Z, Kou Z
Drug design, development and therapy 2021;15:2857-2868
Drug design, development and therapy 2021;15:2857-2868
A-FABP-PTEN/AKT Regulates Insulin Resistance in Preadipocyte Cell 3T3-L1 Cells.
Wu R, Wang H, Huangfu J, Xiao R
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Diabetes, metabolic syndrome and obesity : targets and therapy 2021;14:2103-2110
Histone demethylase JMJD3 protects against renal fibrosis by suppressing TGFβ and Notch signaling and preserving PTEN expression.
Yu C, Xiong C, Tang J, Hou X, Liu N, Bayliss G, Zhuang S
Theranostics 2021;11(6):2706-2721
Theranostics 2021;11(6):2706-2721
MiR-454-3p Promotes Oxaliplatin Resistance by Targeting PTEN in Colorectal Cancer.
Qian XL, Zhou F, Xu S, Jiang J, Chen ZP, Wang SK, Zuo Y, Ni C
Frontiers in oncology 2021;11:638537
Frontiers in oncology 2021;11:638537
miR-4461 Regulates the Proliferation and Metastasis of Ovarian Cancer Cells and Cisplatin Resistance.
Dou L, Zhang Y
Frontiers in oncology 2021;11:614035
Frontiers in oncology 2021;11:614035
Hsa_circ_0006232 promotes laryngeal squamous cell cancer progression through FUS-mediated EZH2 stabilization.
Wu T, Wang G, Zeng X, Sun Z, Li S, Wang W, Yu B
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811
Cell cycle (Georgetown, Tex.) 2021 Sep;20(18):1799-1811
Abnormally elevated ubiquilin‑1 expression in breast cancer regulates metastasis and stemness via AKT signaling.
Feng X, Cao A, Qin T, Zhang Q, Fan S, Wang B, Song B, Yu X, Li L
Oncology reports 2021 Nov;46(5)
Oncology reports 2021 Nov;46(5)
miR-638 suppresses proliferation by negatively regulating high mobility group A1 in ovarian cancer cells.
Ma L, Zhang W, Jin Y, Bai X, Yu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1319
Experimental and therapeutic medicine 2021 Nov;22(5):1319
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
Vicenin-2 inhibits the Helicobacterium pylori infection associated gastric carcinogenic events through modulation of PI3K/AKT and Nrf2 signaling in GES-1 cells.
Zhang Y, Sun J, Dong Y, Shen X, Zhang Z
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22680
Journal of biochemical and molecular toxicology 2021 Mar;35(3):e22680
DEHP-elicited small extracellular vesicles miR-26a-5p promoted metastasis in nearby normal A549 cells.
Qin Y, Zhang J, Avellán-Llaguno RD, Zhang X, Huang Q
Environmental pollution (Barking, Essex : 1987) 2021 Mar 1;272:116005
Environmental pollution (Barking, Essex : 1987) 2021 Mar 1;272:116005
Improvement of hyperlipidemia by aerobic exercise in mice through a regulatory effect of miR-21a-5p on its target genes.
Zhao J, Song Y, Zeng Y, Chen L, Yan F, Chen A, Wu B, Wang Y
Scientific reports 2021 Jun 7;11(1):11966
Scientific reports 2021 Jun 7;11(1):11966
Ginsenoside Rh2 alleviates ulcerative colitis by regulating the STAT3/miR-214 signaling pathway.
Chen X, Xu T, Lv X, Zhang J, Liu S
Journal of ethnopharmacology 2021 Jun 28;274:113997
Journal of ethnopharmacology 2021 Jun 28;274:113997
Serum exosomes from young rats improve the reduced osteogenic differentiation of BMSCs in aged rats with osteoporosis after fatigue loading in vivo.
Xun J, Li C, Liu M, Mei Y, Zhou Q, Wu B, Xie F, Liu Y, Dai R
Stem cell research & therapy 2021 Jul 27;12(1):424
Stem cell research & therapy 2021 Jul 27;12(1):424
Hypoxic pancreatic stellate cell-derived exosomal mirnas promote proliferation and invasion of pancreatic cancer through the PTEN/AKT pathway.
Cao W, Zeng Z, He Z, Lei S
Aging 2021 Feb 26;13(5):7120-7132
Aging 2021 Feb 26;13(5):7120-7132
PKCα mediated by the PI3K/Akt-FOXA1 cascade facilitates cypermethrin-induced hyperthyroidism.
Ha M, Huang X, Li L, Lu D, Liu C
The Science of the total environment 2021 Feb 25;757:143727
The Science of the total environment 2021 Feb 25;757:143727
Hypoxia-inducible factor-1α promotes proliferation of airway smooth muscle cells through miRNA-103-mediated signaling pathway under hypoxia.
Zhang C, Gao J, Zhu S
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
In vitro cellular & developmental biology. Animal 2021 Dec;57(10):944-952
Circular RNA circRAB31 acts as a miR-885-5psponge to suppress gastric cancer progressionvia the PTEN/PI3K/AKT pathway.
Liang X, Qin C, Yu G, Guo X, Cheng A, Zhang H, Wang Z
Molecular therapy oncolytics 2021 Dec 17;23:501-514
Molecular therapy oncolytics 2021 Dec 17;23:501-514
EZH2-Inhibited MicroRNA-454-3p Promotes M2 Macrophage Polarization in Glioma.
Qi B, Yang C, Zhu Z, Chen H
Frontiers in cell and developmental biology 2020;8:574940
Frontiers in cell and developmental biology 2020;8:574940
Exosome-Delivered LncHEIH Promotes Gastric Cancer Progression by Upregulating EZH2 and Stimulating Methylation of the GSDME Promoter.
Lu Y, Hou K, Li M, Wu X, Yuan S
Frontiers in cell and developmental biology 2020;8:571297
Frontiers in cell and developmental biology 2020;8:571297
Upregulation of C Terminus of Hsc70-Interacting Protein Attenuates Apoptosis and Procoagulant Activity and Facilitates Brain Repair After Traumatic Brain Injury.
Chen H, Jing Y, Xu Z, Yang D, Ju S, Guo Y, Tian H, Xue L
Frontiers in neuroscience 2020;14:925
Frontiers in neuroscience 2020;14:925
Lapatinib‑induced inhibition of ovarian function is counteracted by the STAT3 pathway both in vivo and in vitro.
Liao Q, Feng X, Li X, Chen G, Chen J, Yang B, Li K, Ai J
Oncology reports 2020 Sep;44(3):1127-1135
Oncology reports 2020 Sep;44(3):1127-1135
Targeting DNA to the endoplasmic reticulum efficiently enhances gene delivery and therapy.
Qin B, Yuan X, Jiang M, Yin H, Luo Z, Zhang J, Zhu C, Li X, Shi Y, Luo L, Du Y, You J
Nanoscale 2020 Sep 21;12(35):18249-18262
Nanoscale 2020 Sep 21;12(35):18249-18262
SET8 suppression mediates high glucose-induced vascular endothelial inflammation via the upregulation of PTEN.
Shen X, Chen X, Wang J, Liu J, Wang Z, Hua Q, Wu Q, Su Y, He H, Hu Y, Meng Z, Xiong W, Zhu M
Experimental & molecular medicine 2020 Oct;52(10):1715-1729
Experimental & molecular medicine 2020 Oct;52(10):1715-1729
LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN.
Li Y, Zhang M, Li F
Histology and histopathology 2020 Oct;35(10):1171-1180
Histology and histopathology 2020 Oct;35(10):1171-1180
KIF15 contributes to cell proliferation and migration in breast cancer.
Gao X, Zhu L, Lu X, Wang Y, Li R, Jiang G
Human cell 2020 Oct;33(4):1218-1228
Human cell 2020 Oct;33(4):1218-1228
HOTAIR maintains the stemness of ovarian cancer stem cells via the miR-206/TBX3 axis.
Zhang Y, Guo J, Cai E, Cai J, Wen Y, Lu S, Li X, Han Q, Jiang J, Li T, Wang Z
Experimental cell research 2020 Oct 15;395(2):112218
Experimental cell research 2020 Oct 15;395(2):112218
Lamin B1 deficiency promotes malignancy and predicts poor prognosis in gastric cancer.
Yu ZY, Jiang XY, Zhao RR, Luo CJ, Ren YX, Ma ZJ, Ye HL, Shi WG, Wang C, Jiao ZY
Neoplasma 2020 Nov;67(6):1303-1313
Neoplasma 2020 Nov;67(6):1303-1313
MAGI-2 downregulation: a potential predictor of tumor progression and early recurrence in Han Chinese patients with prostate cancer.
Cao Z, Ji J, Wang FB, Kong C, Xu H, Xu YL, Chen X, Yu YW, Sun YH
Asian journal of andrology 2020 Nov-Dec;22(6):616-622
Asian journal of andrology 2020 Nov-Dec;22(6):616-622
Self-responsive co-delivery system for remodeling tumor intracellular microenvironment to promote PTEN-mediated anti-tumor therapy.
Wang Y, Wang R, Wu S, An J, Liang Y, Hou L, Zhang Z
Nanoscale 2020 May 7;12(17):9392-9403
Nanoscale 2020 May 7;12(17):9392-9403
Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota.
Wang D, Zhu X, Tang X, Li H, Yizhen X, Chen D
Journal of food science 2020 Jun;85(6):1872-1890
Journal of food science 2020 Jun;85(6):1872-1890
Neuroprotective effects of miR-532-5p against ischemic stroke.
Mu J, Cheng X, Zhong S, Chen X, Zhao C
Metabolic brain disease 2020 Jun;35(5):753-763
Metabolic brain disease 2020 Jun;35(5):753-763
ChREBP-β regulates thermogenesis in brown adipose tissue.
Wei C, Ma X, Su K, Qi S, Zhu Y, Lin J, Wang C, Yang R, Chen X, Wang W, Zhang WJ
The Journal of endocrinology 2020 Jun;245(3):343-356
The Journal of endocrinology 2020 Jun;245(3):343-356
Effect of STAT3 mediated epigenetic regulation in pre-eclampsia: an analysis of trial data.
Zhang XL, Pan J, Wang G, Li H, Wang JL, Jiang XM, Zhao XY
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
European review for medical and pharmacological sciences 2020 Jun;24(11):5843-5855
LukS-PV Inhibits Hepatocellular Carcinoma Progression by Downregulating HDAC2 Expression.
Wang Z, Yu W, Qiang Y, Xu L, Ma F, Ding P, Shi L, Chang W, Mei Y, Ma X
Molecular therapy oncolytics 2020 Jun 26;17:547-561
Molecular therapy oncolytics 2020 Jun 26;17:547-561
Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro.
Tan Y, Yin L, Sun Z, Shao S, Chen W, Man X, Du Y, Chen Y
International journal of biological macromolecules 2020 Jun 15;153:349-356
International journal of biological macromolecules 2020 Jun 15;153:349-356
Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling.
Dai H, Li M, Yang W, Sun X, Wang P, Wang X, Su J, Wang X, Hu X, Zhao M
Aging 2020 Jun 12;12(12):11717-11731
Aging 2020 Jun 12;12(12):11717-11731
miRNA‑342 suppresses renal interstitial fibrosis in diabetic nephropathy by targeting SOX6.
Jiang ZH, Tang YZ, Song HN, Yang M, Li B, Ni CL
International journal of molecular medicine 2020 Jan;45(1):45-52
International journal of molecular medicine 2020 Jan;45(1):45-52
MiR-214-3p exacerbates kidney damages and inflammation induced by hyperlipidemic pancreatitis complicated with acute renal injury.
Yan Z, Zang B, Gong X, Ren J, Wang R
Life sciences 2020 Jan 15;241:117118
Life sciences 2020 Jan 15;241:117118
Alginate oligosaccharide protects endothelial cells against oxidative stress injury via integrin-α/FAK/PI3K signaling.
Zhao J, Han Y, Wang Z, Zhang R, Wang G, Mao Y
Biotechnology letters 2020 Dec;42(12):2749-2758
Biotechnology letters 2020 Dec;42(12):2749-2758
LINC00673 exerts oncogenic function in cervical cancer by negatively regulating miR-126-5p expression and activates PTEN/PI3K/AKT signaling pathway.
Shi WJ, Liu H, Ge YF, Wu D, Tan YJ, Shen YC, Wang H, Xu H
Cytokine 2020 Dec;136:155286
Cytokine 2020 Dec;136:155286
Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway.
Yu M, Liu W, Li J, Lu J, Lu H, Jia W, Liu F
Stem cell research & therapy 2020 Aug 12;11(1):350
Stem cell research & therapy 2020 Aug 12;11(1):350
Long non-coding RNA MAGI2-AS3 inhibits breast cancer cell migration and invasion via sponging microRNA-374a.
Du S, Hu W, Zhao Y, Zhou H, Wen W, Xu M, Zhao P, Liu K
Cancer biomarkers : section A of Disease markers 2019;24(3):269-277
Cancer biomarkers : section A of Disease markers 2019;24(3):269-277
Atorvastatin Inhibits Breast Cancer Cells by Downregulating PTEN/AKT Pathway via Promoting Ras Homolog Family Member B (RhoB).
Ma Q, Gao Y, Xu P, Li K, Xu X, Gao J, Qi Y, Xu J, Yang Y, Song W, He X, Liu S, Yuan X, Yin W, He Y, Pan W, Wei L, Zhang J
BioMed research international 2019;2019:3235021
BioMed research international 2019;2019:3235021
LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b.
Guo J, Li Y, Duan H, Yuan L
Cancer cell international 2019;19:156
Cancer cell international 2019;19:156
Hypoxic non-small-cell lung cancer cell-derived exosomal miR-21 promotes resistance of normoxic cell to cisplatin.
Dong C, Liu X, Wang H, Li J, Dai L, Li J, Xu Z
OncoTargets and therapy 2019;12:1947-1956
OncoTargets and therapy 2019;12:1947-1956
MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7.
Feng C, So HI, Yin S, Su X, Xu Q, Wang S, Duan W, Zhang E, Sun C, Xu Z
Frontiers in pharmacology 2019;10:940
Frontiers in pharmacology 2019;10:940
Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.
Zhang D, Ren L, Zhao M, Yang C, Liu X, Zhang H, Jiang Y, Sun X, Li T, Cui L, Hu X
Frontiers in immunology 2019;10:1550
Frontiers in immunology 2019;10:1550
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Wu L, Yuan W, Chen J, Zhou Z, Shu Y, Ji J, Liu Z, Tang Q, Zhang X, Shu X
Pediatric research 2019 Oct;86(4):460-470
Pediatric research 2019 Oct;86(4):460-470
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway.
Liu S, Zhang S, Lv X, Lu J, Ren C, Zeng Z, Zheng L, Zhou X, Fu H, Zhou D, Chen Y
International immunopharmacology 2019 Oct;75:105768
International immunopharmacology 2019 Oct;75:105768
The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure.
Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, Tan Y, Niu Y, Duan H, Mai B, Chen S, Yu J, Luan T, Chen L, Xing X, Li Q, Xiao Y, Dong G, Niu Y, Aschner M, Zhang R, Zheng Y, Chen W
Environment international 2019 Oct;131:104943
Environment international 2019 Oct;131:104943
The preoperative neutrophil-to-lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving radical prostatectomy.
Cao Z, Ji J, Zhang C, Wang F, Xu H, Yu Y, Sun Y
Cancer medicine 2019 Mar;8(3):1004-1012
Cancer medicine 2019 Mar;8(3):1004-1012
Down-regulation of miR-543 expression increases the sensitivity of colorectal cancer cells to 5-Fluorouracil through the PTEN/PI3K/AKT pathway.
Liu G, Zhou J, Dong M
Bioscience reports 2019 Mar 29;39(3)
Bioscience reports 2019 Mar 29;39(3)
Long noncoding RNA DGCR5 suppresses gastric cancer progression by acting as a competing endogenous RNA of PTEN and BTG1.
Xu Y, Zhang G, Zou C, Gong Z, Wang S, Liu J, Ma G, Liu X, Zhang W, Jiang P
Journal of cellular physiology 2019 Jul;234(7):11999-12010
Journal of cellular physiology 2019 Jul;234(7):11999-12010
Evaluation of differentially expressed microRNAs in vitrified oocytes by next generation sequencing.
Li J, Yang X, Liu F, Song Y, Liu Y
The international journal of biochemistry & cell biology 2019 Jul;112:134-140
The international journal of biochemistry & cell biology 2019 Jul;112:134-140
Triptolide impairs thioredoxin system by suppressing Notch1-mediated PTEN/Akt/Txnip signaling in hepatocytes.
Shen F, Xiong Z, Kong J, Wang L, Cheng Y, Jin J, Huang Z
Toxicology letters 2019 Jan;300:105-115
Toxicology letters 2019 Jan;300:105-115
Calpain2 but not calpain1 mediated by calpastatin following glutamate-induced regulated necrosis in rat retinal neurons.
Wang S, Huang Y, Yan Y, Zhou H, Wang M, Liao L, Wang Z, Chen D, Ji D, Xia X, Liu F, Huang J, Xiong K
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2019 Jan;221:57-67
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 2019 Jan;221:57-67
YY1-regulated LINC00152 promotes triple negative breast cancer progression by affecting on stability of PTEN protein.
Shen X, Zhong J, Yu P, Zhao Q, Huang T
Biochemical and biophysical research communications 2019 Feb 5;509(2):448-454
Biochemical and biophysical research communications 2019 Feb 5;509(2):448-454
Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma.
Guo J, Fu W, Xiang M, Zhang Y, Zhou K, Xu CR, Li L, Kuang D, Ye F
Current medical science 2019 Dec;39(6):929-937
Current medical science 2019 Dec;39(6):929-937
Morin Inhibits Proliferation and Induces Apoptosis by Modulating the miR-188-5p/PTEN/AKT Regulatory Pathway in CML Cells.
Nie ZY, Yang L, Liu XJ, Yang Z, Yang GS, Zhou J, Qin Y, Yu J, Jiang LL, Wen JK, Luo JM
Molecular cancer therapeutics 2019 Dec;18(12):2296-2307
Molecular cancer therapeutics 2019 Dec;18(12):2296-2307
A panel of serum exosomal microRNAs as predictive markers for chemoresistance in advanced colorectal cancer.
Jin G, Liu Y, Zhang J, Bian Z, Yao S, Fei B, Zhou L, Yin Y, Huang Z
Cancer chemotherapy and pharmacology 2019 Aug;84(2):315-325
Cancer chemotherapy and pharmacology 2019 Aug;84(2):315-325
Stepwise detection and evaluation reveal miR-10b and miR-222 as a remarkable prognostic pair for glioblastoma.
Sun B, Zhao X, Ming J, Liu X, Liu D, Jiang C
Oncogene 2019 Aug;38(33):6142-6157
Oncogene 2019 Aug;38(33):6142-6157
MicroRNA-200b and microRNA-200c are up-regulated in PCOS granulosa cell and inhibit KGN cell proliferation via targeting PTEN.
He T, Sun Y, Zhang Y, Zhao S, Zheng Y, Hao G, Shi Y
Reproductive biology and endocrinology : RB&E 2019 Aug 17;17(1):68
Reproductive biology and endocrinology : RB&E 2019 Aug 17;17(1):68
Proscillaridin A Promotes Oxidative Stress and ER Stress, Inhibits STAT3 Activation, and Induces Apoptosis in A549 Lung Adenocarcinoma Cells.
Maryam A, Mehmood T, Yan Q, Li Y, Khan M, Ma T
Oxidative medicine and cellular longevity 2018;2018:3853409
Oxidative medicine and cellular longevity 2018;2018:3853409
Proscillaridin A induces apoptosis, inhibits STAT3 activation and augments doxorubicin toxicity in prostate cancer cells.
He Y, Khan M, Yang J, Yao M, Yu S, Gao H
International journal of medical sciences 2018;15(8):832-839
International journal of medical sciences 2018;15(8):832-839
miR-217 Promotes Cardiac Hypertrophy and Dysfunction by Targeting PTEN.
Nie X, Fan J, Li H, Yin Z, Zhao Y, Dai B, Dong N, Chen C, Wang DW
Molecular therapy. Nucleic acids 2018 Sep 7;12:254-266
Molecular therapy. Nucleic acids 2018 Sep 7;12:254-266
Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway.
Mu Z, Sun Q
Molecular medicine reports 2018 Nov;18(5):4603-4610
Molecular medicine reports 2018 Nov;18(5):4603-4610
LASP1 promotes nasopharyngeal carcinoma progression through negatively regulation of the tumor suppressor PTEN.
Gao Q, Tang L, Wu L, Li K, Wang H, Li W, Wu J, Li M, Wang S, Zhao L
Cell death & disease 2018 Mar 12;9(3):393
Cell death & disease 2018 Mar 12;9(3):393
Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN.
Ran H, Zhu Y, Deng R, Zhang Q, Liu X, Feng M, Zhong J, Lin S, Tong X, Su Q
Journal of experimental & clinical cancer research : CR 2018 Mar 12;37(1):54
Journal of experimental & clinical cancer research : CR 2018 Mar 12;37(1):54
Osthole inhibits the PI3K/AKT signaling pathway via activation of PTEN and induces cell cycle arrest and apoptosis in esophageal squamous cell carcinoma.
Zhu X, Li Z, Li T, Long F, Lv Y, Liu L, Liu X, Zhan Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:502-509
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:502-509
Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition.
Wang Y, Zhang S, Liu J, Fang B, Yao J, Cheng B
Molecular medicine reports 2018 Jul;18(1):911-919
Molecular medicine reports 2018 Jul;18(1):911-919
Identification of differential gene expression profile from peripheral blood cells of military pilots with hypertension by RNA sequencing analysis.
Zhao XC, Yang SH, Yan YQ, Zhang X, Zhang L, Jiao B, Jiang S, Yu ZB
BMC medical genomics 2018 Jul 11;11(1):59
BMC medical genomics 2018 Jul 11;11(1):59
Inhibition of Rad51 sensitizes breast cancer cells with wild-type PTEN to olaparib.
Zhao Q, Guan J, Zhang Z, Lv J, Wang Y, Liu L, Zhou Q, Mao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:165-168
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Oct;94:165-168
Regulation of ERK and AKT pathways by hepatitis B virus X protein via the Notch1 pathway in hepatocellular carcinoma.
Liao B, Zhou H, Liang H, Li C
International journal of oncology 2017 Nov;51(5):1449-1459
International journal of oncology 2017 Nov;51(5):1449-1459
MiR-106b and miR-93 regulate cell progression by suppression of PTEN via PI3K/Akt pathway in breast cancer.
Li N, Miao Y, Shan Y, Liu B, Li Y, Zhao L, Jia L
Cell death & disease 2017 May 18;8(5):e2796
Cell death & disease 2017 May 18;8(5):e2796
The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
Wang Y, Chen F, Yang Z, Zhao M, Zhang S, Gao Y, Feng J, Yang G, Zhang W, Ye L, Zhang X
Scientific reports 2017 May 18;7(1):2070
Scientific reports 2017 May 18;7(1):2070
PTEN/PI3k/AKT Regulates Macrophage Polarization in Emphysematous mice.
Lu J, Xie L, Liu C, Zhang Q, Sun S
Scandinavian journal of immunology 2017 Jun;85(6):395-405
Scandinavian journal of immunology 2017 Jun;85(6):395-405
Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer.
Xu J, Liu D, Niu H, Zhu G, Xu Y, Ye D, Li J, Zhang Q
Journal of experimental & clinical cancer research : CR 2017 Jan 26;36(1):19
Journal of experimental & clinical cancer research : CR 2017 Jan 26;36(1):19
Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways.
Zhang C, Li C, Chen S, Li Z, Ma L, Jia X, Wang K, Bao J, Liang Y, Chen M, Li P, Su H, Lee SM, Liu K, Wan JB, He C
Scientific reports 2017 Jan 23;7:41082
Scientific reports 2017 Jan 23;7:41082
MicroRNA-130b targets PTEN to mediate drug resistance and proliferation of breast cancer cells via the PI3K/Akt signaling pathway.
Miao Y, Zheng W, Li N, Su Z, Zhao L, Zhou H, Jia L
Scientific reports 2017 Feb 6;7:41942
Scientific reports 2017 Feb 6;7:41942
MicroRNA-106a regulates phosphatase and tensin homologue expression and promotes the proliferation and invasion of ovarian cancer cells.
Chen L, Zhang F, Sheng XG, Zhang SQ, Chen YT, Liu BW
Oncology reports 2016 Oct;36(4):2135-41
Oncology reports 2016 Oct;36(4):2135-41
Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway.
Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, Shen L, Luo A, Wang S
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
Cell cycle (Georgetown, Tex.) 2016 Nov;15(21):2895-2905
FOXP1 forkhead transcription factor is associated with the pathogenesis of endometrial cancer.
Mizunuma M, Yokoyama Y, Futagami M, Horie K, Watanabe J, Mizunuma H
Heliyon 2016 May;2(5):e00116
Heliyon 2016 May;2(5):e00116
Combination of microRNA-21 and microRNA-146a Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction in Mice.
Huang W, Tian SS, Hang PZ, Sun C, Guo J, Du ZM
Molecular therapy. Nucleic acids 2016 Mar 15;5(3):e296
Molecular therapy. Nucleic acids 2016 Mar 15;5(3):e296
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Niu X, Fu N, Du J, Wang R, Wang Y, Zhao S, Du H, Wang B, Zhang Y, Sun D, Nan Y
FEBS letters 2016 Aug;590(16):2709-24
FEBS letters 2016 Aug;590(16):2709-24
Paper-based microreactor array for rapid screening of cell signaling cascades.
Huang CH, Lei KF, Tsang NM
Lab on a chip 2016 Aug 7;16(15):2911-20
Lab on a chip 2016 Aug 7;16(15):2911-20
Modeling glands with PTEN deficient cells and microscopic methods for assessing PTEN loss: endometrial cancer as a model.
Eritja N, Santacana M, Maiques O, Gonzalez-Tallada X, Dolcet X, Matias-Guiu X
Methods (San Diego, Calif.) 2015 May;77-78:31-40
Methods (San Diego, Calif.) 2015 May;77-78:31-40
Best practice for PTEN gene and protein assessment in anatomic pathology.
Carvalho KC, Maia BM, Omae SV, Rocha AA, Covizzi LP, Vassallo J, Rocha RM, Soares FA
Acta histochemica 2014 Jan;116(1):25-31
Acta histochemica 2014 Jan;116(1):25-31
miR-19a acts as an oncogenic microRNA and is up-regulated in bladder cancer.
Feng Y, Liu J, Kang Y, He Y, Liang B, Yang P, Yu Z
Journal of experimental & clinical cancer research : CR 2014 Aug 10;33(1):67
Journal of experimental & clinical cancer research : CR 2014 Aug 10;33(1):67
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