Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- AF847 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rabbit Polyclonal PTEN Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human, mouse, and rat PTEN in Western blots.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references A novel role for GSK3β as a modulator of Drosha microprocessor activity and MicroRNA biogenesis.
Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer.
TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma.
Tumor suppressor PTEN in breast cancer: heterozygosity, mutations and protein expression.
Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice.
Fletcher CE, Godfrey JD, Shibakawa A, Bushell M, Bevan CL
Nucleic acids research 2017 Mar 17;45(5):2809-2828
Nucleic acids research 2017 Mar 17;45(5):2809-2828
Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer.
Bianchini G, Kiermaier A, Bianchi GV, Im YH, Pienkowski T, Liu MC, Tseng LM, Dowsett M, Zabaglo L, Kirk S, Szado T, Eng-Wong J, Amler LC, Valagussa P, Gianni L
Breast cancer research : BCR 2017 Feb 9;19(1):16
Breast cancer research : BCR 2017 Feb 9;19(1):16
TGF-β induces phosphorylation of phosphatase and tensin homolog: implications for fibrosis of the trabecular meshwork tissue in glaucoma.
Tellios N, Belrose JC, Tokarewicz AC, Hutnik C, Liu H, Leask A, Motolko M, Iijima M, Parapuram SK
Scientific reports 2017 Apr 11;7(1):812
Scientific reports 2017 Apr 11;7(1):812
Tumor suppressor PTEN in breast cancer: heterozygosity, mutations and protein expression.
Kechagioglou P, Papi RM, Provatopoulou X, Kalogera E, Papadimitriou E, Grigoropoulos P, Nonni A, Zografos G, Kyriakidis DA, Gounaris A
Anticancer research 2014 Mar;34(3):1387-400
Anticancer research 2014 Mar;34(3):1387-400
Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice.
Ruffolo SC, Forsell PK, Yuan X, Desmarais S, Himms-Hagen J, Cromlish W, Wong KK, Kennedy BP
The Journal of biological chemistry 2007 Oct 19;282(42):30423-33
The Journal of biological chemistry 2007 Oct 19;282(42):30423-33
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human PTEN by Simple WesternTM. Detection of Human PTEN by Simple WesternTM.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of Human/Mouse/Rat PTEN by Western Blot. Detection of Human/Mouse/Rat PTEN by Western Blot.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- PTEN in Human Liver. PTEN in Human Liver.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of PTEN in Human PBMC lymphocytes by Flow Cytometry. Detection of PTEN in Human PBMC lymphocytes by Flow Cytometry.