11344-1-AP

antibody from Proteintech Group

Targeting: HDGF HMG1L2

Provider product page for 11344-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [22]
Comments [0]
Validations
Western blot [1]
Immunoprecipitation [1]
Immunohistochemistry [4]

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Product number: 11344-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#11344-1-AP, RRID:AB_2232950
Product name: HDGF antibody
Antibody type: Polyclonal
Description: KD/KO validated HDGF antibody (Cat. #11344-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

HDGF protein structure - 11344-1-AP shown in red.

Submitted references Gint4.T-siHDGF chimera-capped mesoporous silica nanoparticles encapsulating temozolomide for synergistic glioblastoma therapy.

Fei H, Jin Y, Jiang N, Zhou Y, Wei N, Liu Y, Miao J, Zhang L, Li R, Zhang A, Du S
Biomaterials 2024 Apr;306:122479

BLM promotes malignancy in PCa by inducing KRAS expression and RhoA suppression via its interaction with HDGF and activation of MAPK/ERK pathway.

Guo Y, Xu H, Huang M, Ruan Y
Journal of cell communication and signaling 2023 Sep;17(3):757-772

Nucleophilic covalent ligand discovery for the cysteine redoxome.

Fu L, Jung Y, Tian C, Ferreira RB, Cheng R, He F, Yang J, Carroll KS
Nature chemical biology 2023 Nov;19(11):1309-1319

Clinicopathological features and immunophenotype of Silva pattern system in endocervical adenocarcinoma.

Zeng C, Wu JK, Lu X
International journal of experimental pathology 2023 Jun;104(3):140-150

NAP1L1 promotes the growth of colon cancer by activating HDGF/DDX5.

Liang X, Tang Z, Zhang Y, Sun Y, Wang J
Acta biochimica et biophysica Sinica 2022 Sep 25;54(9):1234-1243

RNA-m6A modification of HDGF mediated by Mettl3 aggravates the progression of atherosclerosis by regulating macrophages polarization via energy metabolism reprogramming.

Zheng L, Chen X, Yin Q, Gu J, Chen J, Chen M, Zhang Y, Dong M, Jiang H, Yin N, Chen H, Li X
Biochemical and biophysical research communications 2022 Dec 20;635:120-127

NAP1L1 Functions as a Tumor Promoter via Recruiting Hepatoma-Derived Growth Factor/c-Jun Signal in Hepatocellular Carcinoma.

Zhang YW, Chen Q, Li B, Li HY, Zhao XK, Xiao YY, Liu S, Zuo S
Frontiers in cell and developmental biology 2021;9:659680

NAP1L1 interacts with hepatoma-derived growth factor to recruit c-Jun inducing breast cancer growth.

Liu S, Zhang Y, Cui S, Song D, Li B, Chen Q, Yao G, Gong B
Cancer cell international 2021 Nov 13;21(1):605

LncRNA SNHG3 promotes cell proliferation and invasion through the miR-384/hepatoma-derived growth factor axis in breast cancer.

Ma Q, Qi X, Lin X, Li L, Chen L, Hu W
Human cell 2020 Jan;33(1):232-242

HDGF and PRKCA upregulation is associated with a poor prognosis in patients with lung adenocarcinoma.

Jiang H, Fu Q, Song X, Ge C, Li R, Li Z, Zeng B, Li C, Wang Y, Xue Y, Luo R, Fang W
Oncology letters 2019 Nov;18(5):4936-4946

Upregulation of miR‑95-3p inhibits growth of osteosarcoma by targeting HDGF.

Liu X, Ma W, Ma J, Xiao L, Hao D
Pathology, research and practice 2019 Aug;215(8):152492

Role of hepatoma-derived growth factor in promoting de novo lipogenesis and tumorigenesis in hepatocellular carcinoma.

Min X, Wen J, Zhao L, Wang K, Li Q, Huang G, Liu J, Zhao X
Molecular oncology 2018 Sep;12(9):1480-1497

Hepatoma-derived growth factor promotes growth and metastasis of hepatocellular carcinoma cells.

Yang GY, Zhang AQ, Wang J, Li CH, Wang XQ, Pan K, Zhou C, Dong JH
Cell biochemistry and function 2016 Jun;34(4):274-85

Downregulation of the expression of HDGF attenuates malignant biological behaviors of hilar cholangiocarcinoma cells.

Liu Y, Sun J, Yang G, Liu Z, Guo S, Zhao R, Xu K, Wu X, Zhang Z
Molecular medicine reports 2015 Sep;12(3):4713-4719

Proteomic analysis of cell proliferation in a human hepatic cell line (HL-7702) induced by perfluorooctane sulfonate using iTRAQ.

Cui R, Zhang H, Guo X, Cui Q, Wang J, Dai J
Journal of hazardous materials 2015 Dec 15;299:361-70

High nuclear expression of HDGF correlates with disease progression and poor prognosis in human endometrial carcinoma.

Wang L, Jiang Q, Hua S, Zhao M, Wu Q, Fu Q, Fang W, Guo S
Disease markers 2014;2014:298795

Identification of hepatoma-derived growth factor as a potential prognostic and diagnostic marker for extrahepatic cholangiocarcinoma.

Han Y, Zhang W, Liu Y
World journal of surgery 2013 Oct;37(10):2419-27

Upregulation of nucleus HDGF predicts poor prognostic outcome in patients with penile squamous cell carcinoma bypass VEGF-A and Ki-67.

Li D, Han Z, Liu J, Zhang X, Ren J, Yan L, Liu H, Xu Z
Medical oncology (Northwood, London, England) 2013 Dec;30(4):702

Expression and clinical significance of hepatoma-derived growth factor as a prognostic factor in human hilar cholangiocarcinoma.

Liu YF, Zhao R, Guo S, Wang XQ, Lian PL, Chen YG, Xu KS
Annals of surgical oncology 2011 Mar;18(3):872-9

Increased expression of hepatoma-derived growth factor correlates with poor prognosis in human nasopharyngeal carcinoma.

Wang S, Fang W
Histopathology 2011 Jan;58(2):217-24

Overexpressed HDGF as an independent prognostic factor is involved in poor prognosis in Chinese patients with liver cancer.

Zhou Y, Zhou N, Fang W, Huo J
Diagnostic pathology 2010 Sep 16;5:58

Identification of glia maturation factor beta as an independent prognostic predictor for serous ovarian cancer.

Li YL, Ye F, Cheng XD, Hu Y, Zhou CY, Lü WG, Xie X
European journal of cancer (Oxford, England : 1990) 2010 Jul;46(11):2104-18

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HeLa cells were subjected to SDS PAGE followed by western blot with 11344-1-AP(HDGF antibody) at dilution of 1:2000
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: IP Result of anti-HDGF (IP:11344-1-AP, 3ug; Detection:11344-1-AP 1:1000) with HepG2 cells lysate 3000ug.
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human lung cancer using 11344-1-AP(HDGF antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The HDGF antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HDGF. This antibody recognizes human,mouse,rat antigen. The HDGF antibody has been validated for the following applications: ELISA, IP, WB, IHC analysis.
Appendix: 11344-1-AP.pdf

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human ovary tumor using 11344-1-AP(HDGF antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human ovary tumor using 11344-1-AP(HDGF antibody) at dilution of 1:100 (under 40x lens)
Sample type: tissue