340201

FCRL4 antibody from BioLegend
CD307d, FCRH4, IGFP2, IRTA1
Immunoprecipitation
Recommended by provider
Flow cytometry
Recommended by provider

Antibody data

Product number
340201
Provider
BioLegend
Product name
Purified anti-human CD307d (FcRL4)
Provider product page
BioLegend - 340201
Antibody type
Monoclonal
Antigen
P815 cells transfected with FcRL4
Description
FcRL4 (Fc receptor-like 4) is a 57 kD single pass type I transmembrane protein that exhibits 4 Ig like C2 domains. Also known as ITRA1, IGFP2, and FcRH4, FcRL4 is predominately found on a subset of memory B cells. Activation of FcRL4 contributes to B cell receptor inhibition through activation of the tyrosine kinases SHP-1 and 2. FcRL4's nascent loci is 1q23.1; however, breakpoint mutations are associated with multiple myeloma and non-Hodgkins lymphoma. Increased FcRL4 expression on memory B cells has also been observed in HIV viremic patients. FcRL4 predominately binds aggregated IgA, binds weakly with IgG3 and IgG4, and does not bind IgG1 and IgG2. 
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Isotype
IgG
Vial size
25 µg
Concentration
0.5 mg/ml
Storage
The antibody solution should be stored undiluted at 4°C.
Provider Type Product Number
- No reagents -