340204

antibody from BioLegend

Targeting: FCRL4 CD307d, FCRH4, IGFP2, IRTA1

Antibody data

Submit

Validation data

Product number: 340204 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#340204, RRID:AB_2104578
Product name: PE anti-human CD307d (FcRL4)
Antibody type: Monoclonal
Antigen: P815 cells transfected with FcRL4
Description: FcRL4 (Fc receptor-like 4) is a 57 kD single pass type I transmembrane protein that exhibits 4 Ig like C2 domains. Also known as ITRA1, IGFP2, and FcRH4, FcRL4 is predominately found on a subset of memory B cells. Activation of FcRL4 contributes to B cell receptor inhibition through activation of the tyrosine kinases SHP-1 and 2. FcRL4's nascent loci is 1q23.1; however, breakpoint mutations are associated with multiple myeloma and non-Hodgkins lymphoma. Increased FcRL4 expression on memory B cells has also been observed in HIV viremic patients. FcRL4 predominately binds aggregated IgA, binds weakly with IgG3 and IgG4, and does not bind IgG1 and IgG2.
Reactivity: Human
Host: Mouse
Conjugate: Yellow dye
Isotype: IgG
Vial size: 100 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

FCRL4 protein structure - 340204 shown in red.