Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN1881479 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Kin of IRRE Like (Drosophila) (NEPH1) (C-Term), (AA 505-534) antibody
- Antibody type
- Polyclonal
- Antigen
- This KIRREL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-534 amino acids from the C-terminal region of human KIRREL.
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term,AA 505-534
- Antibody clone number
- RB41570
- Vial size
- 400 μL
- Concentration
- 0.5 mg/mL
Submitted references Association analysis of podocyte slit diaphragm genes as candidates for diabetic nephropathy.
Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1.
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.
NEPH1 defines a novel family of podocin interacting proteins.
Ihalmo P, Wessman M, Kaunisto MA, Kilpikari R, Parkkonen M, Forsblom C, Holthöfer H, Groop PH, FinnDiane Study Group
Diabetologia 2008 Jan;51(1):86-90
Diabetologia 2008 Jan;51(1):86-90
Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1.
Wagner MC, Rhodes G, Wang E, Pruthi V, Arif E, Saleem MA, Wean SE, Garg P, Verma R, Holzman LB, Gattone V, Molitoris BA, Nihalani D
The Journal of biological chemistry 2008 Dec 19;283(51):35579-89
The Journal of biological chemistry 2008 Dec 19;283(51):35579-89
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity.
Hartleben B, Schweizer H, Lübben P, Bartram MP, Möller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB
The Journal of biological chemistry 2008 Aug 22;283(34):23033-8
The Journal of biological chemistry 2008 Aug 22;283(34):23033-8
NEPH1 defines a novel family of podocin interacting proteins.
Sellin L, Huber TB, Gerke P, Quack I, Pavenstädt H, Walz G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 Jan;17(1):115-7
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003 Jan;17(1):115-7
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- KIRREL Antibody (C-term) (ABIN1881479) western blot analysis in MDA-MB231 cell line lysates (35 μg/lane). This demonstrates the KIRREL antibody detected the KIRREL protein (arrow).