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- Antibody Data
- Antigen structure
- References [18]
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- Product number
- 17178-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17178-1-AP, RRID:AB_2206757
- Product name
- TNP1 antibody
- Antibody type
- Polyclonal
- Description
- TNP1 antibody (Cat. #17178-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references 5- methylcytidine effectively improves spermatogenesis recovery in busulfan-induced oligoasthenospermia mice.
Disrupted intercellular bridges and spermatogenesis in fatty acyl-CoA reductase 1 knockout mice: A new model of ether lipid deficiency.
Absence of CEP78 causes photoreceptor and sperm flagella impairments in mice and a human individual.
Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.
Multi-omics analyses reveal the mechanisms of Arsenic-induced male reproductive toxicity in mice.
CDKN2AIP is critical for spermiogenesis and germ cell development.
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.
CFAP43-mediated intra-manchette transport is required for sperm head shaping and flagella formation.
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice.
PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange during Spermiogenesis.
Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†.
PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis.
The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice.
Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis.
Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis.
TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis.
Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis.
Molecular analysis of cell type-specific gene expression profile during mouse spermatogenesis by laser microdissection and qRT-PCR.
Wang C, Ye T, Bao J, Dong J, Wang W, Li C, Ding H, Chen H, Wang X, Shi J
European journal of pharmacology 2024 Mar 15;967:176405
European journal of pharmacology 2024 Mar 15;967:176405
Disrupted intercellular bridges and spermatogenesis in fatty acyl-CoA reductase 1 knockout mice: A new model of ether lipid deficiency.
Pan B, Yuan S, Mayernik L, Yap YT, Moin K, Chung CS, Maddipati K, Krawetz SA, Zhang Z, Hess RA, Chen X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22908
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22908
Absence of CEP78 causes photoreceptor and sperm flagella impairments in mice and a human individual.
Zhu T, Zhang Y, Sheng X, Zhang X, Chen Y, Zhu H, Guo Y, Qi Y, Zhao Y, Zhou Q, Chen X, Guo X, Zhao C
eLife 2023 Feb 9;12
eLife 2023 Feb 9;12
Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.
Zhou J, Zeng L, Zhang Y, Wang M, Li Y, Jia Y, Wu L, Su P
The Science of the total environment 2022 Nov 15;847:157500
The Science of the total environment 2022 Nov 15;847:157500
Multi-omics analyses reveal the mechanisms of Arsenic-induced male reproductive toxicity in mice.
Peng Z, Yang Q, Yeerken R, Chen J, Liu X, Li X
Journal of hazardous materials 2022 Feb 15;424(Pt C):127548
Journal of hazardous materials 2022 Feb 15;424(Pt C):127548
CDKN2AIP is critical for spermiogenesis and germ cell development.
Cao Y, Sun Q, Chen Z, Lu J, Geng T, Ma L, Zhang Y
Cell & bioscience 2022 Aug 21;12(1):136
Cell & bioscience 2022 Aug 21;12(1):136
Silica nanoparticles inhibiting the differentiation of round spermatid and chromatin remodeling of haploid period via MIWI in mice.
Liu J, Li X, Zhou G, Zhang Y, Sang Y, Wang J, Li Y, Ge W, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2021 Sep 1;284:117446
Environmental pollution (Barking, Essex : 1987) 2021 Sep 1;284:117446
CFAP43-mediated intra-manchette transport is required for sperm head shaping and flagella formation.
Yu Y, Wang J, Zhou L, Li H, Zheng B, Yang S
Zygote (Cambridge, England) 2021 Feb;29(1):75-81
Zygote (Cambridge, England) 2021 Feb;29(1):75-81
Silica nanoparticles induce spermatogenesis disorders via L3MBTL2-DNA damage-p53 apoptosis and RNF8-ubH2A/ubH2B pathway in mice.
Liu J, Li X, Zhou G, Sang Y, Zhang Y, Zhao Y, Ge W, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):114974
Environmental pollution (Barking, Essex : 1987) 2020 Oct;265(Pt A):114974
PHF7 Modulates BRDT Stability and Histone-to-Protamine Exchange during Spermiogenesis.
Kim CR, Noda T, Kim H, Kim G, Park S, Na Y, Oura S, Shimada K, Bang I, Ahn JY, Kim YR, Oh SK, Choi HJ, Kim JS, Jung I, Lee H, Okada Y, Ikawa M, Baek SH
Cell reports 2020 Jul 28;32(4):107950
Cell reports 2020 Jul 28;32(4):107950
Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†.
Devlin DJ, Nozawa K, Ikawa M, Matzuk MM
Biology of reproduction 2020 Aug 4;103(2):205-222
Biology of reproduction 2020 Aug 4;103(2):205-222
PHF7 is a novel histone H2A E3 ligase prior to histone-to-protamine exchange during spermiogenesis.
Wang X, Kang JY, Wei L, Yang X, Sun H, Yang S, Lu L, Yan M, Bai M, Chen Y, Long J, Li N, Li D, Huang J, Lei M, Shao Z, Yuan W, Zuo E, Lu K, Liu MF, Li J
Development (Cambridge, England) 2019 Jul 10;146(13)
Development (Cambridge, England) 2019 Jul 10;146(13)
The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice.
Morohoshi A, Nakagawa T, Nakano S, Nagasawa Y, Nakayama K
Developmental biology 2019 Jan 15;445(2):178-188
Developmental biology 2019 Jan 15;445(2):178-188
Raptor directs Sertoli cell cytoskeletal organization and polarity in the mouse testis.
Xiong Z, Wang C, Wang Z, Dai H, Song Q, Zou Z, Xiao B, Zhao AZ, Bai X, Chen Z
Biology of reproduction 2018 Dec 1;99(6):1289-1302
Biology of reproduction 2018 Dec 1;99(6):1289-1302
Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis.
Liu S, Yu H, Liu Y, Liu X, Zhang Y, Bu C, Yuan S, Chen Z, Xie G, Li W, Xu B, Yang J, He L, Jin T, Xiong Y, Sun L, Liu X, Han C, Cheng Z, Liang J, Shang Y
Molecular cell 2017 Sep 7;67(5):853-866.e5
Molecular cell 2017 Sep 7;67(5):853-866.e5
TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis.
Jha KN, Tripurani SK, Johnson GR
Journal of cell science 2017 May 15;130(10):1835-1844
Journal of cell science 2017 May 15;130(10):1835-1844
Ubiquitination-Deficient Mutations in Human Piwi Cause Male Infertility by Impairing Histone-to-Protamine Exchange during Spermiogenesis.
Gou LT, Kang JY, Dai P, Wang X, Li F, Zhao S, Zhang M, Hua MM, Lu Y, Zhu Y, Li Z, Chen H, Wu LG, Li D, Fu XD, Li J, Shi HJ, Liu MF
Cell 2017 Jun 1;169(6):1090-1104.e13
Cell 2017 Jun 1;169(6):1090-1104.e13
Molecular analysis of cell type-specific gene expression profile during mouse spermatogenesis by laser microdissection and qRT-PCR.
Esakky P, Hansen DA, Drury AM, Moley KH
Reproductive sciences (Thousand Oaks, Calif.) 2013 Mar;20(3):238-52
Reproductive sciences (Thousand Oaks, Calif.) 2013 Mar;20(3):238-52
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The TNP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TNP1. This antibody recognizes human, mouse, rat antigen. The TNP1 antibody has been validated for the following applications: ELISA, WB analysis.
