Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 20590-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20590-1-AP, RRID:AB_10694420
- Product name
- AIM2 antibody
- Antibody type
- Polyclonal
- Description
- AIM2 antibody (Cat. #20590-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Autophagy-Based Unconventional Secretory for AIM2 Inflammasome Drives DNA Damage Resistance During Intervertebral Disc Degeneration.
Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma.
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation.
Expression and localization of absent in melanoma 2 in the injured spinal cord.
Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis.
Analysis of the expression of NLRP3 and AIM2 in periapical lesions with apical periodontitis and microbial analysis outside the apical segment of teeth.
AIM2 contributes to the maintenance of intestinal integrity via Akt and protects against Salmonella mucosal infection.
Correlation of AIM2 expression in peripheral blood mononuclear cells from humans with acute and chronic hepatitis B.
Li S, Liao Z, Luo R, Song Y, Wang K, Feng X, Ou Y, Wu X, Zhang Y, Gao Y, Yin H, Yang C
Frontiers in cell and developmental biology 2021;9:672847
Frontiers in cell and developmental biology 2021;9:672847
Caspase-11 and AIM2 inflammasome are involved in smoking-induced COPD and lung adenocarcinoma.
Colarusso C, Terlizzi M, Lamort AS, Cerqua I, Roviezzo F, Stathopoulos G, Pinto A, Sorrentino R
Oncotarget 2021 May 25;12(11):1057-1071
Oncotarget 2021 May 25;12(11):1057-1071
Aspergillus fumigatus-Stimulated Human Corneal Epithelial Cells Induce Pyroptosis of THP-1 Macrophages by Secreting TSLP.
Ji Q, Wang L, Liu J, Wu Y, Lv H, Wen Y, Shi L, Qu B, Szentmáry N
Inflammation 2021 Apr;44(2):682-692
Inflammation 2021 Apr;44(2):682-692
NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology.
He X, Yang W, Zeng Z, Wei Y, Gao J, Zhang B, Li L, Liu L, Wan Y, Zeng Q, Gong Z, Liu L, Zhang H, Li Y, Yang S, Hu T, Wu L, Masliah E, Huang S, Cao H
Cellular & molecular immunology 2020 Mar;17(3):283-299
Cellular & molecular immunology 2020 Mar;17(3):283-299
Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Mycobacterium bovis Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation.
Liao Y, Hussain T, Liu C, Cui Y, Wang J, Yao J, Chen H, Song Y, Sabir N, Hussain M, Zhao D, Zhou X
Frontiers in immunology 2019;10:268
Frontiers in immunology 2019;10:268
Expression and localization of absent in melanoma 2 in the injured spinal cord.
Wang SN, Guo XY, Tang J, Ding SQ, Shen L, Wang R, Ma SF, Hu JG, Lü HZ
Neural regeneration research 2019 Mar;14(3):542-552
Neural regeneration research 2019 Mar;14(3):542-552
Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis.
Guo Q, Wu Y, Hou Y, Liu Y, Liu T, Zhang H, Fan C, Guan H, Li Y, Shan Z, Teng W
Frontiers in immunology 2018;9:1197
Frontiers in immunology 2018;9:1197
Analysis of the expression of NLRP3 and AIM2 in periapical lesions with apical periodontitis and microbial analysis outside the apical segment of teeth.
Ran S, Liu B, Gu S, Sun Z, Liang J
Archives of oral biology 2017 Jun;78:39-47
Archives of oral biology 2017 Jun;78:39-47
AIM2 contributes to the maintenance of intestinal integrity via Akt and protects against Salmonella mucosal infection.
Hu GQ, Song PX, Li N, Chen W, Lei QQ, Yu SX, Zhang XJ, Du CT, Deng XM, Han WY, Yang YJ
Mucosal immunology 2016 Sep;9(5):1330-9
Mucosal immunology 2016 Sep;9(5):1330-9
Correlation of AIM2 expression in peripheral blood mononuclear cells from humans with acute and chronic hepatitis B.
Wu DL, Xu GH, Lu SM, Ma BL, Miao NZ, Liu XB, Cheng YP, Feng JH, Liu ZG, Feng-Ding, Na-Liu, Li WQ, Zhao YR
Human immunology 2013 May;74(5):514-21
Human immunology 2013 May;74(5):514-21
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 20590-1-AP(AIM2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AIM2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human AIM2. This antibody recognizes human antigen. The AIM2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.