HPA031365

antibody from Atlas Antibodies

Targeting: AIM2 PYHIN4

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA031365

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA031365, RRID:AB_10601332

Product name

Anti-AIM2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human AIM2, Gene description: absent in melanoma 2, Alternative Gene Names: PYHIN4, Validated applications: IHC, Uniprot ID: O14862, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.3 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Characterization of two transcriptomic subtypes of marker-null large cell carcinoma of the lung suggests different origin and potential new therapeutic perspectives

Simbolo M, Centonze G, Gkountakos A, Monti V, Maisonneuve P, Golovco S, Sabella G, Del Gobbo A, Gobbo S, Ferrero S, Fabbri A, Pardo C, Garzone G, Prinzi N, Pusceddu S, Testi A, Rolli L, Mangogna A, Bercich L, Benvenuti M, Bria E, Pilotto S, Berruti A, Pastorino U, Capella C, Infante M, Milella M, Scarpa A, Milione M
Virchows Archiv 2024;484(5):777-788

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Cytosolic DNA sensor AIM2 promotes KRAS‐driven lung cancer independent of inflammasomes

Alanazi M, Weng T, McLeod L, Gearing L, Smith J, Kumar B, Saad M, Jenkins B
Cancer Science 2024;115(6):1834-1850

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The cytosolic DNA sensor AIM2 promotes Helicobacter‐induced gastric pathology via the inflammasome

Dawson R, Deswaerte V, West A, Sun E, Wray‐McCann G, Livis T, Kumar B, Rodriguez E, Gabay C, Ferrero R, Jenkins B
Immunology & Cell Biology 2023;101(5):444-457

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Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema

Ruwanpura S, McLeod L, Dousha L, Seow H, West A, West A, Weng T, Alanazi M, MacDonald M, King P, Bardin P, Gabay C, Klinman D, Bozinovski S, Vlahos R, Anderson G, Rose-John S, Saad M, Jenkins B
Proceedings of the National Academy of Sciences 2022;119(36)

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Inflammasome activity in leucocytes decreases with abdominal aortic aneurysm progression

Erhart P, Cakmak S, Grond‑Ginsbach C, Hakimi M, B�ckler D, Dihlmann S
International Journal of Molecular Medicine 2019

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Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells

Benedict C, Eichholz K, Bru T, Tran T, Fernandes P, Welles H, Mennechet F, Manel N, Alves P, Perreau M, Kremer E
PLOS Pathogens 2016;12(9):e1005871