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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations [0]
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- Product number
- HPA031365 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA031365, RRID:AB_10601332
- Product name
- Anti-AIM2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human AIM2, Gene description: absent in melanoma 2, Alternative Gene Names: PYHIN4, Validated applications: IHC, Uniprot ID: O14862, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Characterization of two transcriptomic subtypes of marker-null large cell carcinoma of the lung suggests different origin and potential new therapeutic perspectives
Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes.
The cytosolic DNA sensor AIM2 promotes Helicobacter-induced gastric pathology via the inflammasome.
Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema.
Inflammasome activity in leucocytes decreases with abdominal aortic aneurysm progression
Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells
Simbolo M, Centonze G, Gkountakos A, Monti V, Maisonneuve P, Golovco S, Sabella G, Del Gobbo A, Gobbo S, Ferrero S, Fabbri A, Pardo C, Garzone G, Prinzi N, Pusceddu S, Testi A, Rolli L, Mangogna A, Bercich L, Benvenuti M, Bria E, Pilotto S, Berruti A, Pastorino U, Capella C, Infante M, Milella M, Scarpa A, Milione M
Virchows Archiv 2024;484(5):777-788
Virchows Archiv 2024;484(5):777-788
Cytosolic DNA sensor AIM2 promotes KRAS-driven lung cancer independent of inflammasomes.
Alanazi M, Weng T, McLeod L, Gearing LJ, Smith JA, Kumar B, Saad MI, Jenkins BJ
Cancer science 2024 Jun;115(6):1834-1850
Cancer science 2024 Jun;115(6):1834-1850
The cytosolic DNA sensor AIM2 promotes Helicobacter-induced gastric pathology via the inflammasome.
Dawson RE, Deswaerte V, West AC, Sun E, Wray-McCann G, Livis T, Kumar B, Rodriguez E, Gabay C, Ferrero RL, Jenkins BJ
Immunology and cell biology 2023 May;101(5):444-457
Immunology and cell biology 2023 May;101(5):444-457
Cross-talk between IL-6 trans-signaling and AIM2 inflammasome/IL-1β axes bridge innate immunity and epithelial apoptosis to promote emphysema.
Ruwanpura SM, McLeod L, Dousha LF, Seow HJ, West AC, West AJ, Weng T, Alanazi M, MacDonald M, King PT, Bardin PG, Gabay C, Klinman DM, Bozinovski S, Vlahos R, Anderson GP, Rose-John S, Saad MI, Jenkins BJ
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 6;119(36):e2201494119
Proceedings of the National Academy of Sciences of the United States of America 2022 Sep 6;119(36):e2201494119
Inflammasome activity in leucocytes decreases with abdominal aortic aneurysm progression
Erhart P, Cakmak S, Grond‑Ginsbach C, Hakimi M, B�ckler D, Dihlmann S
International Journal of Molecular Medicine 2019
International Journal of Molecular Medicine 2019
Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells
Benedict C, Eichholz K, Bru T, Tran T, Fernandes P, Welles H, Mennechet F, Manel N, Alves P, Perreau M, Kremer E
PLOS Pathogens 2016;12(9):e1005871
PLOS Pathogens 2016;12(9):e1005871
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