Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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Validation data
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- Product number
- ABIN2843099 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Absent in Melanoma 2 (AIM2) (AA 4-32), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 4-32, N-Term
- Antibody clone number
- RB23659
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Restoration of absent in melanoma 2 (AIM2) induces G2/M cell cycle arrest and promotes invasion of colorectal cancer cells.
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers.
Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2.
Patsos G, Germann A, Gebert J, Dihlmann S
International journal of cancer 2010 Apr 15;126(8):1838-1849
International journal of cancer 2010 Apr 15;126(8):1838-1849
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, Latz E, Fitzgerald KA
Nature 2009 Mar 26;458(7237):514-8
Nature 2009 Mar 26;458(7237):514-8
The putative tumor suppressor AIM2 is frequently affected by different genetic alterations in microsatellite unstable colon cancers.
Woerner SM, Kloor M, Schwitalle Y, Youmans H, Doeberitz Mv, Gebert J, Dihlmann S
Genes, chromosomes & cancer 2007 Dec;46(12):1080-9
Genes, chromosomes & cancer 2007 Dec;46(12):1080-9
Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2.
Cresswell KS, Clarke CJ, Jackson JT, Darcy PK, Trapani JA, Johnstone RW
Biochemical and biophysical research communications 2005 Jan 14;326(2):417-24
Biochemical and biophysical research communications 2005 Jan 14;326(2):417-24
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS