66902-1-Ig

antibody from Proteintech Group

Targeting: AIM2 PYHIN4

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

66902-1-Ig

Provider

Proteintech Group

Product name

AIM2 antibody

Antibody type

Monoclonal

Description

AIM2 antibody (Cat. #66902-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat, rabbit and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Rat, Rabbit

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3E12A8

Vial size

20ul, 150ul

References

Submitted references

Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis.

Li H, Ni H, Li Y, Zhou A, Qin X, Li Y, Che L, Mo H, Qin C, Li J
Cell death discovery 2024 May 13;10(1):227

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Transcriptomic analysis reveals molecular characterization and immune landscape of PANoptosis-related genes in atherosclerosis.

Zheng Z, Li K, Yang Z, Wang X, Shen C, Zhang Y, Lu H, Yin Z, Sha M, Ye J, Zhu L
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2024 Jun;73(6):961-978

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Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions.

Hou Y, Chu X, Park JH, Zhu Q, Hussain M, Li Z, Madsen HB, Yang B, Wei Y, Wang Y, Fang EF, Croteau DL, Bohr VA
Alzheimer's & dementia : the journal of the Alzheimer's Association 2024 Jun;20(6):4212-4233

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Tangeretin Attenuates Cerebral Ischemia-Reperfusion-Induced Neuronal Pyroptosis by Inhibiting AIM2 Inflammasome Activation via Regulating NRF2.

You G, Zheng L, Zhang Y, Zhang Y, Wang Y, Guo W, Liu H, Tatiana P, Vladimir K, Zan J
Inflammation 2024 Feb;47(1):145-158

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Farnesoid X receptor overexpression prevents hepatic steatosis through inhibiting AIM2 inflammasome activation in nonalcoholic fatty liver disease.

Xu S, Kong L, Li L, Wang C, Gu J, Luo H, Meng Q
Biochimica et biophysica acta. Molecular basis of disease 2024 Feb;1870(2):166930

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PKIB involved in the metastasis and survival of osteosarcoma.

Wan R, Yang G, Liu Q, Fu X, Liu Z, Miao H, Liu H, Huang W
Frontiers in oncology 2022;12:965838

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Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway.

Zhou J, Zeng L, Zhang Y, Wang M, Li Y, Jia Y, Wu L, Su P
The Science of the total environment 2022 Nov 15;847:157500

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Increased susceptibility of irradiated mice to Aspergillus fumigatus infection via NLRP3/GSDMD pathway in pulmonary bronchial epithelia.

Wu DM, He M, Zhao YY, Deng SH, Liu T, Zhang T, Zhang F, Wang YY, Xu Y
Cell communication and signaling : CCS 2022 Jun 27;20(1):98

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Prohibitin 1 regulates mtDNA release and downstream inflammatory responses.

Liu H, Fan H, He P, Zhuang H, Liu X, Chen M, Zhong W, Zhang Y, Zhen C, Li Y, Jiang H, Meng T, Xu Y, Zhao G, Feng D
The EMBO journal 2022 Dec 15;41(24):e111173

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STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis.

Dawson RE, Deswaerte V, West AC, Tang K, West AJ, Balic JJ, Gearing LJ, Saad MI, Yu L, Wu Y, Bhathal PS, Kumar B, Chakrabarti JT, Zavros Y, Oshima H, Klinman DM, Oshima M, Tan P, Jenkins BJ
Gut 2022 Aug;71(8):1515-1531

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Establishment of tumor inflammasome clusters with distinct immunogenomic landscape aids immunotherapy.

Liang Q, Wu J, Zhao X, Shen S, Zhu C, Liu T, Cui X, Chen L, Wei C, Cheng P, Cheng W, Wu A
Theranostics 2021;11(20):9884-9903