BS3401

antibody from Bioworld Technology, Inc

Targeting: ATP1A2 FHM2, MHP2

Western blot (Data presented on provider website)

Antibody Data

Product number

BS3401

Provider

Bioworld Technology, Inc

Product name

Na+/K+ ATPase Ï«2 (R1007) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids C-terminus of Human Na+/K+-ATPase Ï«2.

Description

The ubiquitously expressed sodium/potassium-ATPase exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, sodium/potassium-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, Ï«, ÉÇ and ?, comprise to form the sodium/potassium-ATPase oligomer. The Ï«-subunit contains the binding sites for ATP and the cations. The glycosylated ÉÇ-subunit ensures correct folding and membrane insertion of the Ï«-subunits. The small ?-subunit colocalizes with the Ï«-subunit in nephron segments where it increases the affinity of sodium/potassium ATPase for ATP. The ÉÇ-subunit, but not the ?-subunit, is essential for normal activity of sodium/potassium ATPase.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.