Antibody data
- Antibody Data
- Antigen structure
- References [19]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 16836-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16836-1-AP, RRID:AB_2061149
- Product name
- ATP1A2 antibody
- Antibody type
- Polyclonal
- Description
- ATP1A2 antibody (Cat. #16836-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Identification of a novel Scn3b mutation in a Chinese Brugada syndrome pedigree: implications for Nav1.5 electrophysiological properties and intracellular distribution of Nav1.5 and Navβ3.
Crym-positive striatal astrocytes gate perseverative behaviour.
Understanding Propofol's Protective Mechanism in Tubular Epithelial Cells: Mitigating Pyroptosis via the miR-143-3p/ATPase Na + /K + Transporting Subunit Alpha 2 Pathway in Renal Ischemia-Reperfusion.
DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice.
Comprehensive analysis identified a reduction in ATP1A2 mediated by ARID3A in abdominal aortic aneurysm.
Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Identification of Three Potential Prognostic Genes in Platinum-Resistant Ovarian Cancer via Integrated Bioinformatics Analysis.
The Specific Connexin 43-Inhibiting Peptide Gap26 Improved Alveolar Development of Neonatal Rats With Hyperoxia Exposure.
Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes.
Tumour blood flow for prediction of human prostate cancer aggressiveness: a study with Rubidium-82 PET, MRI and Na(+)/K(+)-ATPase-density.
Comprehensive analysis of the expression of sodium/potassium-ATPase α subunits and prognosis of ovarian serous cystadenocarcinoma.
Evaluating the involvement of cerebral microvascular endothelial Na(+)/K(+)-ATPase and Na(+)-K(+)-2Cl(-) co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration.
Expression of Na(+)/K(+)-ATPase Was Affected by Salinity Change in Pacific abalone Haliotis discus hannai.
Role of RAB5A in FSHR-mediated signal transduction in human granulosa cells.
A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study.
The α2β2 isoform combination dominates the astrocytic Na(+) /K(+) -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation.
Tanshinone IIA Sodium sulfonate regulates antioxidant system, inflammation, and endothelial dysfunction in atherosclerosis by downregulation of CLIC1.
Elimination of undifferentiated human embryonic stem cells by cardiac glycosides.
Retinoschisin is linked to retinal Na/K-ATPase signaling and localization.
Fan J, Wang SH, Cao LL, Li WJ, Sun SX, Luo SL, Pan YC, Tan WL, Wu TY, Liu Z, Yu BB
Frontiers in cardiovascular medicine 2024;11:1320687
Frontiers in cardiovascular medicine 2024;11:1320687
Crym-positive striatal astrocytes gate perseverative behaviour.
Ollivier M, Soto JS, Linker KE, Moye SL, Jami-Alahmadi Y, Jones AE, Divakaruni AS, Kawaguchi R, Wohlschlegel JA, Khakh BS
Nature 2024 Mar;627(8003):358-366
Nature 2024 Mar;627(8003):358-366
Understanding Propofol's Protective Mechanism in Tubular Epithelial Cells: Mitigating Pyroptosis via the miR-143-3p/ATPase Na + /K + Transporting Subunit Alpha 2 Pathway in Renal Ischemia-Reperfusion.
Kan H, Zhao M, Wang W, Sun B
Molecular biotechnology 2024 Mar 18;
Molecular biotechnology 2024 Mar 18;
DR region of NKAα1 is a target to ameliorate hepatic lipid metabolism disturbance in obese mice.
Sun HJ, Tan JX, Shan XD, Wang ZC, Wu ZY, Bian JS, Nie XW
Metabolism: clinical and experimental 2023 Aug;145:155579
Metabolism: clinical and experimental 2023 Aug;145:155579
Comprehensive analysis identified a reduction in ATP1A2 mediated by ARID3A in abdominal aortic aneurysm.
Wang Q, Li N, Guo X, Huo B, Li R, Feng X, Fang Z, Zhu XH, Wang Y, Yi X, Wei X, Jiang DS
Journal of cellular and molecular medicine 2022 May;26(10):2866-2880
Journal of cellular and molecular medicine 2022 May;26(10):2866-2880
Homophilic ATP1A1 binding induces activin A secretion to promote EMT of tumor cells and myofibroblast activation.
Chen YI, Chang CC, Hsu MF, Jeng YM, Tien YW, Chang MC, Chang YT, Hu CM, Lee WH
Nature communications 2022 May 26;13(1):2945
Nature communications 2022 May 26;13(1):2945
Identification of Three Potential Prognostic Genes in Platinum-Resistant Ovarian Cancer via Integrated Bioinformatics Analysis.
Zhang X, Wei X, Bai G, Huang X, Hu S, Mao H, Liu P
Cancer management and research 2021;13:8629-8646
Cancer management and research 2021;13:8629-8646
The Specific Connexin 43-Inhibiting Peptide Gap26 Improved Alveolar Development of Neonatal Rats With Hyperoxia Exposure.
Qing C, Xinyi Z, Xuefei Y, Xindong X, Jianhua F
Frontiers in pharmacology 2021;12:587267
Frontiers in pharmacology 2021;12:587267
Rebound effects of NCX3 pharmacological inhibition: A novel strategy to accelerate myelin formation in oligodendrocytes.
Cammarota M, de Rosa V, Pannaccione A, Secondo A, Tedeschi V, Piccialli I, Fiorino F, Severino B, Annunziato L, Boscia F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112111
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Nov;143:112111
Tumour blood flow for prediction of human prostate cancer aggressiveness: a study with Rubidium-82 PET, MRI and Na(+)/K(+)-ATPase-density.
Jochumsen MR, Sörensen J, Pedersen BG, Nyengaard JR, Krag SRP, Frøkiær J, Borre M, Bouchelouche K, Tolbod LP
European journal of nuclear medicine and molecular imaging 2021 Feb;48(2):532-542
European journal of nuclear medicine and molecular imaging 2021 Feb;48(2):532-542
Comprehensive analysis of the expression of sodium/potassium-ATPase α subunits and prognosis of ovarian serous cystadenocarcinoma.
Huang W, Zhang Y, Xu Y, Yang S, Li B, Huang L, Lou G
Cancer cell international 2020;20:309
Cancer cell international 2020;20:309
Evaluating the involvement of cerebral microvascular endothelial Na(+)/K(+)-ATPase and Na(+)-K(+)-2Cl(-) co-transporter in electrolyte fluxes in an in vitro blood-brain barrier model of dehydration.
Lykke K, Assentoft M, Hørlyck S, Helms HC, Stoica A, Toft-Bertelsen TL, Tritsaris K, Vilhardt F, Brodin B, MacAulay N
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2019 Mar;39(3):497-512
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2019 Mar;39(3):497-512
Expression of Na(+)/K(+)-ATPase Was Affected by Salinity Change in Pacific abalone Haliotis discus hannai.
Jia Y, Liu X
Frontiers in physiology 2018;9:1244
Frontiers in physiology 2018;9:1244
Role of RAB5A in FSHR-mediated signal transduction in human granulosa cells.
Zhu K, Li S, Liu J, Hong Y, Chen ZJ, Du Y
Reproduction (Cambridge, England) 2018 Jun;155(6):505-514
Reproduction (Cambridge, England) 2018 Jun;155(6):505-514
A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study.
Liu X, Shen Y, Xie J, Bao H, Cao Q, Wan R, Xu X, Zhou H, Huang L, Xu Z, Zhu W, Hu J, Cheng X, Hong K
PloS one 2017;12(5):e0177532
PloS one 2017;12(5):e0177532
The α2β2 isoform combination dominates the astrocytic Na(+) /K(+) -ATPase activity and is rendered nonfunctional by the α2.G301R familial hemiplegic migraine type 2-associated mutation.
Stoica A, Larsen BR, Assentoft M, Holm R, Holt LM, Vilhardt F, Vilsen B, Lykke-Hartmann K, Olsen ML, MacAulay N
Glia 2017 Nov;65(11):1777-1793
Glia 2017 Nov;65(11):1777-1793
Tanshinone IIA Sodium sulfonate regulates antioxidant system, inflammation, and endothelial dysfunction in atherosclerosis by downregulation of CLIC1.
Zhu J, Xu Y, Ren G, Hu X, Wang C, Yang Z, Li Z, Mao W, Lu D
European journal of pharmacology 2017 Nov 15;815:427-436
European journal of pharmacology 2017 Nov 15;815:427-436
Elimination of undifferentiated human embryonic stem cells by cardiac glycosides.
Lin YT, Wang CK, Yang SC, Hsu SC, Lin H, Chang FP, Kuo TC, Shen CN, Chiang PM, Hsiao M, Lu FL, Lu J
Scientific reports 2017 Jul 13;7(1):5289
Scientific reports 2017 Jul 13;7(1):5289
Retinoschisin is linked to retinal Na/K-ATPase signaling and localization.
Plössl K, Royer M, Bernklau S, Tavraz NN, Friedrich T, Wild J, Weber BHF, Friedrich U
Molecular biology of the cell 2017 Aug 1;28(16):2178-2189
Molecular biology of the cell 2017 Aug 1;28(16):2178-2189
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 16836-1-AP(ATP1A2 antibody) at dilution of 1:1200
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using ATP1A2 antibody 16836-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 16836-1-AP(ATP1A2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 16836-1-AP(ATP1A2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue