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Protein structure
STK36
Serine/threonine kinase 36FU, KIAA1278
This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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| Proteintech Group |  12559-1-AP |
2 references | Polyclonal |
WB
EL
IP
IHC
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| LSBio | LS-C805378 |
Polyclonal |
WB
EL
ICC
IHC
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| Invitrogen Antibodies | 12559-1-AP |
Polyclonal |
WB
IP
IHC
OA
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| NovoPro Bioscience Inc. | 115721 |
Polyclonal |
WB
EL
IP
IHC
|
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| Affinity Biosciences | DF4465 |
Polyclonal |
WB
EL
ICC
IHC
|
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