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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB3492A - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal VEGFR3/Flt-4 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human VEGF R3/Flt-4 in direct ELISAs.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references The distribution and potential prognostic value of SMAD protein expression in chronic lymphocytic leukemia.
Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma.
Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells.
Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib.
Impaired long-term expansion and self-renewal potential of pediatric acute myeloid leukemia-initiating cells by PTK787/ZK 222584.
Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
VEGF-A promotes lymphoma tumour growth by activation of STAT proteins and inhibition of p27(KIP1) via paracrine mechanisms.
Witkowska M, Majchrzak A, Cebula-Obrzut B, Wawrzyniak E, Robak T, Smolewski P
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar;39(3):1010428317694551
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Mar;39(3):1010428317694551
Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma.
Sie M, den Dunnen WF, Lourens HJ, Meeuwsen-de Boer TG, Scherpen FJ, Zomerman WW, Kampen KR, Hoving EW, de Bont ES
PloS one 2015;10(3):e0122555
PloS one 2015;10(3):e0122555
Antiangiogenic cancer drug sunitinib exhibits unexpected proangiogenic effects on endothelial cells.
Norton KA, Han Z, Popel AS, Pandey NB
OncoTargets and therapy 2014;7:1571-82
OncoTargets and therapy 2014;7:1571-82
Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib.
Fiorio Pla A, Brossa A, Bernardini M, Genova T, Grolez G, Villers A, Leroy X, Prevarskaya N, Gkika D, Bussolati B
BMC cancer 2014 Dec 12;14:939
BMC cancer 2014 Dec 12;14:939
Impaired long-term expansion and self-renewal potential of pediatric acute myeloid leukemia-initiating cells by PTK787/ZK 222584.
Weidenaar AC, Ter Elst A, Kampen KR, Meeuwsen-de Boer T, Kamps WA, Schuringa JJ, de Bont ES
Molecular cancer research : MCR 2013 Apr;11(4):339-48
Molecular cancer research : MCR 2013 Apr;11(4):339-48
Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
Nilsson MB, Zage PE, Zeng L, Xu L, Cascone T, Wu HK, Saigal B, Zweidler-McKay PA, Heymach JV
Oncogene 2010 May 20;29(20):2938-49
Oncogene 2010 May 20;29(20):2938-49
VEGF-A promotes lymphoma tumour growth by activation of STAT proteins and inhibition of p27(KIP1) via paracrine mechanisms.
Roorda BD, Ter Elst A, Scherpen FJ, Meeuwsen-de Boer TG, Kamps WA, de Bont ES
European journal of cancer (Oxford, England : 1990) 2010 Mar;46(5):974-82
European journal of cancer (Oxford, England : 1990) 2010 Mar;46(5):974-82
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Detection of VEGF R3/Flt-4 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R3/ Flt-4 APC-conjugated Monoclonal Antibody (Catalog # FAB3492A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.
