Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB3492P - Provider product page
- Provider
- R&D Systems
- Product name
- Human VEGFR3/Flt-4 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human VEGF R3/Flt-4 in direct ELISAs.
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P35916
- Isotype
- IgG
- Antibody clone number
- 54733
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.
Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib.
Expression of VEGF receptors on endothelial cells in mouse skeletal muscle.
Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, Xu X, Zhang G, Azuma R, Liu Q, Liu R, Li L, Amaravadi RK, Xu W, Karakousis G, Gangadhar TC, Schuchter LM, Lieu M, Khare S, Halloran MB, Herlyn M, Kaufman RE
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1652-64
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1652-64
Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib.
Fiorio Pla A, Brossa A, Bernardini M, Genova T, Grolez G, Villers A, Leroy X, Prevarskaya N, Gkika D, Bussolati B
BMC cancer 2014 Dec 12;14:939
BMC cancer 2014 Dec 12;14:939
Expression of VEGF receptors on endothelial cells in mouse skeletal muscle.
Imoukhuede PI, Popel AS
PloS one 2012;7(9):e44791
PloS one 2012;7(9):e44791
Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, Yagita H, Koyanagi M, Kondo Y, Yuo A
Journal of cellular physiology 2008 Oct;217(1):261-80
Journal of cellular physiology 2008 Oct;217(1):261-80
Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
Experimental hematology 2008 May;36(5):545-558
Experimental hematology 2008 May;36(5):545-558
Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.
Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J
The Journal of clinical investigation 2007 Nov;117(11):3369-82
The Journal of clinical investigation 2007 Nov;117(11):3369-82
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
Ball SG, Shuttleworth CA, Kielty CM
The Journal of cell biology 2007 May 7;177(3):489-500
The Journal of cell biology 2007 May 7;177(3):489-500
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of VEGF R3/Flt-4 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R3/ Flt-4 PE-conjugated Monoclonal Antibody (Catalog # FAB3492P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.