FAB3492P

antibody from R&D Systems

Targeting: FLT4 PCL, VEGFR-3, VEGFR3

Flow cytometry (Supportive data in Antibodypedia)

Antibody Data

Product number

FAB3492P

Provider

R&D Systems

Product name

Human VEGFR3/Flt-4 PE-conjugated Antibody

Antibody type

Monoclonal

Description

Protein A or G purified from hybridoma culture supernatant. Detects human VEGF R3/Flt-4 in direct ELISAs.

Reactivity

Human

Host

Mouse

Antigen sequence

P35916


Isotype

IgG

Antibody clone number

54733

Vial size

100 Tests

Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.

References

Submitted references

BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.

Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, Xu X, Zhang G, Azuma R, Liu Q, Liu R, Li L, Amaravadi RK, Xu W, Karakousis G, Gangadhar TC, Schuchter LM, Lieu M, Khare S, Halloran MB, Herlyn M, Kaufman RE
Clinical cancer research : an official journal of the American Association for Cancer Research 2015 Apr 1;21(7):1652-64

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Differential sensitivity of prostate tumor derived endothelial cells to sorafenib and sunitinib.

Fiorio Pla A, Brossa A, Bernardini M, Genova T, Grolez G, Villers A, Leroy X, Prevarskaya N, Gkika D, Bussolati B
BMC cancer 2014 Dec 12;14:939

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Expression of VEGF receptors on endothelial cells in mouse skeletal muscle.

Imoukhuede PI, Popel AS
PloS one 2012;7(9):e44791

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Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.

Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, Yagita H, Koyanagi M, Kondo Y, Yuo A
Journal of cellular physiology 2008 Oct;217(1):261-80

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Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.

Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
Experimental hematology 2008 May;36(5):545-558

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Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.

Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J
The Journal of clinical investigation 2007 Nov;117(11):3369-82

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Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.

Ball SG, Shuttleworth CA, Kielty CM
The Journal of cell biology 2007 May 7;177(3):489-500

Flow cytometry

Supportive validation

Submitted by

R&D Systems (provider)

Main image

Experimental details

Detection of VEGF R3/Flt-4 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R3/ Flt-4 PE-conjugated Monoclonal Antibody (Catalog # FAB3492P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.