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- References [11]
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- Product number
- 17856-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- USP21 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP21 antibody (Cat. #17856-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TET2 stabilized by deubiquitinase USP21 ameliorates cigarette smoke-induced apoptosis in airway epithelial cells.
Guanosine diphosphate-mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer.
Construction and validation of a prognostic signature based on necroptosis-related genes in hepatocellular carcinoma.
Anti-tumor effects of deubiquitinating enzyme inhibitor PR-619 in human chondrosarcoma through reduced cell proliferation and endoplasmic reticulum stress-related apoptosis.
Salt-like transcription factor 4 promotes laryngeal cancer progression through transcriptional activation of ubiquitin-specific protease 21 to stabilize Yin Yang 1.
USP21 contributes to the aggressiveness of laryngeal cancer cells by deubiquitinating and stabilizing AURKA.
RBM47/SNHG5/FOXO3 axis activates autophagy and inhibits cell proliferation in papillary thyroid carcinoma.
PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo Study.
Deubiquitinating Enzyme USP21 Inhibits HIV-1 Replication by Downregulating Tat Expression.
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth.
Luo L, Zeng Z, Li T, Liu X, Cui Y, Tao Y, Li Y, Chen Y
iScience 2024 Mar 15;27(3):109252
iScience 2024 Mar 15;27(3):109252
Guanosine diphosphate-mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer.
Ding JH, Xiao Y, Yang F, Song XQ, Xu Y, Ding XH, Ding R, Shao ZM, Di GH, Jiang YZ
Science translational medicine 2024 Jan 3;16(728):eadg7740
Science translational medicine 2024 Jan 3;16(728):eadg7740
Construction and validation of a prognostic signature based on necroptosis-related genes in hepatocellular carcinoma.
Peng YL, Wang LX, Li MY, Liu LP, Li RS
PloS one 2023;18(2):e0279744
PloS one 2023;18(2):e0279744
Anti-tumor effects of deubiquitinating enzyme inhibitor PR-619 in human chondrosarcoma through reduced cell proliferation and endoplasmic reticulum stress-related apoptosis.
Lin WC, Chiu YL, Kuo KL, Chow PM, Hsu CH, Liao SM, Dong JR, Chang SC, Liu SH, Liu TJ, Hsu FS, Wang KC, Lin YC, Chang CC, Huang KY
American journal of cancer research 2023;13(7):3055-3066
American journal of cancer research 2023;13(7):3055-3066
Salt-like transcription factor 4 promotes laryngeal cancer progression through transcriptional activation of ubiquitin-specific protease 21 to stabilize Yin Yang 1.
Wang QD, Liu LL, Li D, Gao L, Zhang MJ
Pathology international 2023 Mar;73(3):109-119
Pathology international 2023 Mar;73(3):109-119
USP21 contributes to the aggressiveness of laryngeal cancer cells by deubiquitinating and stabilizing AURKA.
Wang QD, Shi T, Xu Y, Liu Y, Zhang MJ
The Kaohsiung journal of medical sciences 2023 Apr;39(4):354-363
The Kaohsiung journal of medical sciences 2023 Apr;39(4):354-363
RBM47/SNHG5/FOXO3 axis activates autophagy and inhibits cell proliferation in papillary thyroid carcinoma.
Qin Y, Sun W, Wang Z, Dong W, He L, Zhang T, Lv C, Zhang H
Cell death & disease 2022 Mar 25;13(3):270
Cell death & disease 2022 Mar 25;13(3):270
PR-619, a General Inhibitor of Deubiquitylating Enzymes, Diminishes Cisplatin Resistance in Urothelial Carcinoma Cells through the Suppression of c-Myc: An In Vitro and In Vivo Study.
Hsu FS, Lin WC, Kuo KL, Chiu YL, Hsu CH, Liao SM, Dong JR, Liu SH, Chang SC, Yang SP, Chen YT, Chang RJ, Huang KH
International journal of molecular sciences 2021 Oct 28;22(21)
International journal of molecular sciences 2021 Oct 28;22(21)
Deubiquitinating Enzyme USP21 Inhibits HIV-1 Replication by Downregulating Tat Expression.
Gao W, Li G, Zhao S, Wang H, Huan C, Zheng B, Jiang C, Zhang W
Journal of virology 2021 Jun 10;95(13):e0046021
Journal of virology 2021 Jun 10;95(13):e0046021
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosis.
Liu Z, Dagley LF, Shield-Artin K, Young SN, Bankovacki A, Wang X, Tang M, Howitt J, Stafford CA, Nachbur U, Fitzgibbon C, Garnish SE, Webb AI, Komander D, Murphy JM, Hildebrand JM, Silke J
The EMBO journal 2021 Dec 1;40(23):e103718
The EMBO journal 2021 Dec 1;40(23):e103718
The deubiquitinase USP21 stabilizes MEK2 to promote tumor growth.
Li W, Cui K, Prochownik EV, Li Y
Cell death & disease 2018 May 1;9(5):482
Cell death & disease 2018 May 1;9(5):482
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP21 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human USP21. This antibody recognizes human antigen. The USP21 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
