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- References [12]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 14575-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14575-1-AP, RRID:AB_2183291
- Product name
- SDHC antibody
- Antibody type
- Polyclonal
- Description
- SDHC antibody (Cat. #14575-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Efficient identification of new small molecules targeting succinate dehydrogenase in non-small cell lung cancer.
Iron addicted colorectal cancers exploit Heme-Complex II axis to resist oxidative cell death.
Comprehensive analysis of the prognosis, tumor microenvironment, and immunotherapy response of SDHs in colon adenocarcinoma.
Congenital cataracts affect the retinal visual cycle and mitochondrial function: A multi-omics study of GJA8 knockout rabbits.
Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer.
MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle.
Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver.
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice.
Quantitative proteomics in A30P*A53T α-synuclein transgenic mice reveals upregulation of Sel1l.
Silva L, Skiados N, Murugavel N, Cover K, Luna N, Gupta MK, Contreras SC, O'Brien TE, Zhang WC
Cancer cell international 2025 Oct 17;25(1):362
Cancer cell international 2025 Oct 17;25(1):362
Iron addicted colorectal cancers exploit Heme-Complex II axis to resist oxidative cell death.
Jain C, Essani M, Kumar R, Das NK, Singhal R, Rossiter NJ, Chen B, Huang W, Lee ZH, Solanki S, Zhang Y, Sajjakulnukit P, Zhang L, Dalal PJ, Hanna DA, McCollum S, Stoffel EM, Greenson JK, Maher LJ, Lyssiotis CA, Banerjee R, Shah YM
bioRxiv : the preprint server for biology 2025 Nov 6;
bioRxiv : the preprint server for biology 2025 Nov 6;
Comprehensive analysis of the prognosis, tumor microenvironment, and immunotherapy response of SDHs in colon adenocarcinoma.
Nan H, Guo P, Fan J, Zeng W, Hu C, Zheng C, Pan B, Cao Y, Ge Y, Xue X, Li W, Lin K
Frontiers in immunology 2023;14:1093974
Frontiers in immunology 2023;14:1093974
Congenital cataracts affect the retinal visual cycle and mitochondrial function: A multi-omics study of GJA8 knockout rabbits.
Sun W, Gu S, Zhang F, Xu M, Chang P, Zhao Y
Journal of proteomics 2023 Sep 15;287:104972
Journal of proteomics 2023 Sep 15;287:104972
Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Li X, Wu F, Günther S, Looso M, Kuenne C, Zhang T, Wiesnet M, Klatt S, Zukunft S, Fleming I, Poschet G, Wietelmann A, Atzberger A, Potente M, Yuan X, Braun T
Nature 2023 Oct;622(7983):619-626
Nature 2023 Oct;622(7983):619-626
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Liu Y, Liu K, Thorne RF, Shi R, Zhang Q, Wu M, Liu L
Cell reports 2023 Feb 28;42(2):112041
Cell reports 2023 Feb 28;42(2):112041
Autophagy supports mitochondrial metabolism through the regulation of iron homeostasis in pancreatic cancer.
Mukhopadhyay S, Encarnación-Rosado J, Lin EY, Sohn ASW, Zhang H, Mancias JD, Kimmelman AC
Science advances 2023 Apr 21;9(16):eadf9284
Science advances 2023 Apr 21;9(16):eadf9284
MDH2 produced OAA is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle.
Molinié T, Cougouilles E, David C, Cahoreau E, Portais JC, Mourier A
Biochimica et biophysica acta. Bioenergetics 2022 Mar 1;1863(3):148532
Biochimica et biophysica acta. Bioenergetics 2022 Mar 1;1863(3):148532
Prevention and regression of megamitochondria and steatosis by blocking mitochondrial fusion in the liver.
Yamada T, Murata D, Kleiner DE, Anders R, Rosenberg AZ, Kaplan J, Hamilton JP, Aghajan M, Levi M, Wang NY, Dawson TM, Yanagawa T, Powers AF, Iijima M, Sesaki H
iScience 2022 Apr 15;25(4):103996
iScience 2022 Apr 15;25(4):103996
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Wang XH, Xu S, Zhou XY, Zhao R, Lin Y, Cao J, Zang WD, Tao H, Xu W, Li MQ, Zhao SM, Jin LP, Zhao JY
Nature communications 2021 Jun 8;12(1):3428
Nature communications 2021 Jun 8;12(1):3428
Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice.
Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG
Nucleic acids research 2018 Jul 27;46(13):6642-6669
Nucleic acids research 2018 Jul 27;46(13):6642-6669
Quantitative proteomics in A30P*A53T α-synuclein transgenic mice reveals upregulation of Sel1l.
Yan J, Zhang P, Jiao F, Wang Q, He F, Zhang Q, Zhang Z, Lv Z, Peng X, Cai H, Tian B
PloS one 2017;12(8):e0182092
PloS one 2017;12(8):e0182092
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 14575-1-AP(SDHC antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SDHC antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SDHC. This antibody recognizes human,mouse,rat antigen. The SDHC antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 14575-1-AP(SDHC antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
