Antibody data
- Antibody Data
- Antigen structure
- References [18]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Flow cytometry [1]
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Validation data
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- Product number
- 12831-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12831-1-AP, RRID:AB_2087822
- Product name
- Alpha E-Catenin antibody
- Antibody type
- Polyclonal
- Description
- Alpha E-Catenin antibody (Cat. #12831-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation.
Capsaicin enhances cisplatin-induced anti-metastasis of nasopharyngeal carcinoma by inhibiting EMT and ERK signaling via serpin family B member 2.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Nogo-B inhibition restricts ulcerative colitis via inhibiting p68/miR-155 signaling pathway.
Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues.
Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.
Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair.
P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer.
Upregulation of CPNE7 in mesenchymal stromal cells promotes oral squamous cell carcinoma metastasis through the NF-κB pathway.
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth.
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
GATA4 is upregulated in nasopharyngeal cancer and facilitates epithelial-mesenchymal transition and metastasis through regulation of SLUG.
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Downregulation of Bmi-1 suppresses epithelial‑mesenchymal transition in melanoma.
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact.
Liu Y, Yang M, Fan L, He Y, Dai E, Liu M, Jiang L, Yang Z, Li S
International journal of biological macromolecules 2024 Feb;258(Pt 1):128570
International journal of biological macromolecules 2024 Feb;258(Pt 1):128570
Capsaicin enhances cisplatin-induced anti-metastasis of nasopharyngeal carcinoma by inhibiting EMT and ERK signaling via serpin family B member 2.
Xu Y, Kong W, Zhao S, Xiong D, Wang Y
Carcinogenesis 2024 Aug 12;45(8):556-568
Carcinogenesis 2024 Aug 12;45(8):556-568
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
Nogo-B inhibition restricts ulcerative colitis via inhibiting p68/miR-155 signaling pathway.
Zheng J, Wang S, Zhang T, Li H, Zhu M, Wei X, Ge Y, Yang X, Zhang S, Xu H, Duan Y, Liu L, Chen Y
International immunopharmacology 2023 Jul;120:110378
International immunopharmacology 2023 Jul;120:110378
Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues.
Qiu Q, Yu X, Chen Q, He X
Autoimmunity 2023 Dec;56(1):2200908
Autoimmunity 2023 Dec;56(1):2200908
Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.
Zhang Y, Ji S, Zhang X, Lu M, Hu Y, Han Y, Shui G, Lam SM, Zou X
International journal of biological sciences 2022;18(13):4963-4983
International journal of biological sciences 2022;18(13):4963-4983
Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair.
Wang J, Liu C, He L, Xie Z, Bai L, Yu W, Wang Z, Lu Y, Gao D, Fu J, Zhang L, Zeng YA
eLife 2022 Mar 14;11
eLife 2022 Mar 14;11
P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer.
Naydenov NG, Lechuga S, Zalavadia A, Mukherjee PK, Gordon IO, Skvasik D, Vidovic P, Huang E, Rieder F, Ivanov AI
Cells 2022 Apr 27;11(9)
Cells 2022 Apr 27;11(9)
Upregulation of CPNE7 in mesenchymal stromal cells promotes oral squamous cell carcinoma metastasis through the NF-κB pathway.
Ji X, Sun T, Xie S, Qian H, Song L, Wang L, Liu H, Feng Q
Cell death discovery 2021 Oct 14;7(1):294
Cell death discovery 2021 Oct 14;7(1):294
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182
Balkan medical journal 2021 May;38(3):177-182
SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth.
Alshargabi R, Sano T, Yamashita A, Takano A, Sanada T, Iwashita M, Shinjo T, Fukuda T, Sanui T, Kishida S, Nishimura F
Scientific reports 2020 Jun 17;10(1):9785
Scientific reports 2020 Jun 17;10(1):9785
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, Chang X, Jin Z, Li J, Zhu Z, Liu B, Su L
Oncogene 2020 Feb;39(7):1414-1428
Oncogene 2020 Feb;39(7):1414-1428
GATA4 is upregulated in nasopharyngeal cancer and facilitates epithelial-mesenchymal transition and metastasis through regulation of SLUG.
Zhou Y, Chang H, Yang B
Experimental and therapeutic medicine 2018 Dec;16(6):5318-5326
Experimental and therapeutic medicine 2018 Dec;16(6):5318-5326
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
Zhou Q, Wang X, Yu Z, Wu X, Chen X, Li J, Zhu Z, Liu B, Su L
Oncogene 2017 Mar 30;36(13):1873-1886
Oncogene 2017 Mar 30;36(13):1873-1886
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Wang Y, Wu N, Sun D, Sun H, Tong D, Liu D, Pang B, Li S, Wei J, Dai J, Liu Y, Bai J, Geng J, Fu S, Jin Y
Cancer science 2017 Jun;108(6):1169-1176
Cancer science 2017 Jun;108(6):1169-1176
Downregulation of Bmi-1 suppresses epithelial‑mesenchymal transition in melanoma.
Liu Y, Chu Z, Li Q, Peng B, Xu S, Lian CG, Geng S
Oncology reports 2017 Jan;37(1):139-146
Oncology reports 2017 Jan;37(1):139-146
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Zhang Y, Zhang X, Huang J, Dong Q
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact.
Zhang C, Zhang H, Yu L, Cao Y
Helicobacter 2014 Oct;19(5):330-42
Helicobacter 2014 Oct;19(5):330-42
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse uterus tissue were subjected to SDS PAGE followed by western blot with 12831-1-AP( CTNNA1 Antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A431 cells using 12831-1-AP( CTNNA1 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Alpha E catenin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Alpha E catenin. This antibody recognizes human,mouse,rat antigen. The Alpha E catenin antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.