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- Antibody Data
- Antigen structure
- References [30]
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- Western blot [1]
- Immunocytochemistry [1]
- Flow cytometry [1]
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- Product number
- 12831-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12831-1-AP, RRID:AB_2087822
- Product name
- Alpha E-Catenin antibody
- Antibody type
- Polyclonal
- Description
- Alpha E-Catenin antibody (Cat. #12831-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Reversibly unlocking the blood-brain barrier: A study on microtubule dynamics modulation using gold nanoparticle-modified reduced graphene oxide.
Ubiquitination degradation of GATA4 by CUL4B promotes ovarian cancer metastasis by inducing lysosomal acidification.
Development and characterization of immortalized mouse intestinal epithelial cell lines.
Exploration and Validation of Key Genes and Immune Infiltration in Alcoholic Hepatitis.
Dexmedetomidine Blocks the ERK Pathway by Inhibiting MAP3K8 to Achieve a Protective Effect in Lung Ischemia/Reperfusion Injury.
Rictor stability mediated by USP9X regulates embryo implantation by participating in lipid metabolism of endometrium†.
UBE2O-mediated ubiquitylation directs cytoplasmic CTNNA1 to promote cell-to-ECM adhesions.
STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins.
Mechanism of trypsin-mediated differentiation of pancreatic progenitor cells into functional islet-like clusters.
PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells.
The TRIP6/LATS1 complex constitutes the tension sensor of α-catenin/vinculin at both bicellular and tricellular junctions.
Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation.
Capsaicin enhances cisplatin-induced anti-metastasis of nasopharyngeal carcinoma by inhibiting EMT and ERK signaling via serpin family B member 2.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells.
Nogo-B inhibition restricts ulcerative colitis via inhibiting p68/miR-155 signaling pathway.
Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues.
Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.
Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair.
P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer.
Upregulation of CPNE7 in mesenchymal stromal cells promotes oral squamous cell carcinoma metastasis through the NF-κB pathway.
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth.
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
GATA4 is upregulated in nasopharyngeal cancer and facilitates epithelial-mesenchymal transition and metastasis through regulation of SLUG.
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Downregulation of Bmi-1 suppresses epithelial‑mesenchymal transition in melanoma.
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact.
Wu J, Cui G, Lin Z, Lin W, Zhang Y, Zhou T, He P, Zhang Y, Yao G
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1676-1695
Ubiquitination degradation of GATA4 by CUL4B promotes ovarian cancer metastasis by inducing lysosomal acidification.
Yin X, Gao R, Geng Y, Mu X, Zhang Y, Ma Y, Chen X, Han F, Chen Z, Li F, He J
Genome biology 2026 Feb 9;27(1)
Genome biology 2026 Feb 9;27(1)
Development and characterization of immortalized mouse intestinal epithelial cell lines.
Zhou JY, Espenschied ST, Lu Q, Karell PE, Lewis KJ, Newhall KP, Han Y, Bambroo M, Job A, Stappenbeck TS
Scientific reports 2026 Feb 11;16(1)
Scientific reports 2026 Feb 11;16(1)
Exploration and Validation of Key Genes and Immune Infiltration in Alcoholic Hepatitis.
Mei Y, Zheng Y, Zhang X, Hu T, Zheng X, Zhang C, Deng Q
Journal of inflammation research 2025;18:8243-8262
Journal of inflammation research 2025;18:8243-8262
Dexmedetomidine Blocks the ERK Pathway by Inhibiting MAP3K8 to Achieve a Protective Effect in Lung Ischemia/Reperfusion Injury.
Hu CH, Qian R, Wang YB, Li LD, Miao CX
The Kaohsiung journal of medical sciences 2025 Sep;41(9):e70045
The Kaohsiung journal of medical sciences 2025 Sep;41(9):e70045
Rictor stability mediated by USP9X regulates embryo implantation by participating in lipid metabolism of endometrium†.
Peng M, He J, Liu X, Mu X, Yin X, Liu T, Chen X, Gao R, Wang Y, Feng Q, Geng Y
Biology of reproduction 2025 Sep 15;113(3):642-656
Biology of reproduction 2025 Sep 15;113(3):642-656
UBE2O-mediated ubiquitylation directs cytoplasmic CTNNA1 to promote cell-to-ECM adhesions.
Xiang D, Wu W, Shi R, Tang X, Zhang X
EMBO reports 2025 Nov;26(22):5431-5458
EMBO reports 2025 Nov;26(22):5431-5458
STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins.
Xie L, Gao L, Fu W, Wu G, Li H, Ning W
PLoS biology 2025 Nov;23(11):e3003227
PLoS biology 2025 Nov;23(11):e3003227
Mechanism of trypsin-mediated differentiation of pancreatic progenitor cells into functional islet-like clusters.
Gao L, Lai JS, Chen H, Qian LX, Hong WJ, Li LC
World journal of diabetes 2025 Jun 15;16(6):102727
World journal of diabetes 2025 Jun 15;16(6):102727
PPM1G dephosphorylates α-catenin to maintain the integrity of adherens junctions and regulates apoptosis in Sertoli cells.
Li X, Liu Q, Wang L, Bu T, Yang X, Gao S, Yun D, Sun F
Molecular and cellular endocrinology 2025 Apr 15;600:112493
Molecular and cellular endocrinology 2025 Apr 15;600:112493
The TRIP6/LATS1 complex constitutes the tension sensor of α-catenin/vinculin at both bicellular and tricellular junctions.
Xie L, Wu G, Liu X, Duan X, Zhou K, Li H, Ning W
European journal of cell biology 2024 Jun;103(2):151426
European journal of cell biology 2024 Jun;103(2):151426
Frameshift variants in the C-terminal of CTNNB1 cause familial exudative vitreoretinopathy by AXIN1-mediated ubiquitin-proteasome degradation condensation.
Liu Y, Yang M, Fan L, He Y, Dai E, Liu M, Jiang L, Yang Z, Li S
International journal of biological macromolecules 2024 Feb;258(Pt 1):128570
International journal of biological macromolecules 2024 Feb;258(Pt 1):128570
Capsaicin enhances cisplatin-induced anti-metastasis of nasopharyngeal carcinoma by inhibiting EMT and ERK signaling via serpin family B member 2.
Xu Y, Kong W, Zhao S, Xiong D, Wang Y
Carcinogenesis 2024 Aug 12;45(8):556-568
Carcinogenesis 2024 Aug 12;45(8):556-568
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells.
Cao L, Wang R, Liu G, Zhang Y, Thorne RF, Zhang XD, Li J, Xia Y, Guo L, Shao F, Gu H, Wu M
EMBO reports 2023 Mar 6;24(3):e55683
EMBO reports 2023 Mar 6;24(3):e55683
Nogo-B inhibition restricts ulcerative colitis via inhibiting p68/miR-155 signaling pathway.
Zheng J, Wang S, Zhang T, Li H, Zhu M, Wei X, Ge Y, Yang X, Zhang S, Xu H, Duan Y, Liu L, Chen Y
International immunopharmacology 2023 Jul;120:110378
International immunopharmacology 2023 Jul;120:110378
Sema3A inactivates the ERK/JNK signalling pathways to alleviate inflammation and oxidative stress in lipopolysaccharide-stimulated rat endothelial cells and lung tissues.
Qiu Q, Yu X, Chen Q, He X
Autoimmunity 2023 Dec;56(1):2200908
Autoimmunity 2023 Dec;56(1):2200908
Human CPTP promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.
Zhang Y, Ji S, Zhang X, Lu M, Hu Y, Han Y, Shui G, Lam SM, Zou X
International journal of biological sciences 2022;18(13):4963-4983
International journal of biological sciences 2022;18(13):4963-4983
Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair.
Wang J, Liu C, He L, Xie Z, Bai L, Yu W, Wang Z, Lu Y, Gao D, Fu J, Zhang L, Zeng YA
eLife 2022 Mar 14;11
eLife 2022 Mar 14;11
P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer.
Naydenov NG, Lechuga S, Zalavadia A, Mukherjee PK, Gordon IO, Skvasik D, Vidovic P, Huang E, Rieder F, Ivanov AI
Cells 2022 Apr 27;11(9)
Cells 2022 Apr 27;11(9)
Upregulation of CPNE7 in mesenchymal stromal cells promotes oral squamous cell carcinoma metastasis through the NF-κB pathway.
Ji X, Sun T, Xie S, Qian H, Song L, Wang L, Liu H, Feng Q
Cell death discovery 2021 Oct 14;7(1):294
Cell death discovery 2021 Oct 14;7(1):294
miR-509-3p Suppresses Migration, Invasion, and Epithelial- Mesenchymal Transition in Melanoma Cells by Targeting Collagen Triple Helix Repeat Containing 1.
Yuan K, Sun Y, Ji Y
Balkan medical journal 2021 May;38(3):177-182
Balkan medical journal 2021 May;38(3):177-182
SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth.
Alshargabi R, Sano T, Yamashita A, Takano A, Sanada T, Iwashita M, Shinjo T, Fukuda T, Sanui T, Kishida S, Nishimura F
Scientific reports 2020 Jun 17;10(1):9785
Scientific reports 2020 Jun 17;10(1):9785
The reciprocal interaction between tumor cells and activated fibroblasts mediated by TNF-α/IL-33/ST2L signaling promotes gastric cancer metastasis.
Zhou Q, Wu X, Wang X, Yu Z, Pan T, Li Z, Chang X, Jin Z, Li J, Zhu Z, Liu B, Su L
Oncogene 2020 Feb;39(7):1414-1428
Oncogene 2020 Feb;39(7):1414-1428
GATA4 is upregulated in nasopharyngeal cancer and facilitates epithelial-mesenchymal transition and metastasis through regulation of SLUG.
Zhou Y, Chang H, Yang B
Experimental and therapeutic medicine 2018 Dec;16(6):5318-5326
Experimental and therapeutic medicine 2018 Dec;16(6):5318-5326
Transducin (β)-like 1 X-linked receptor 1 promotes gastric cancer progression via the ERK1/2 pathway.
Zhou Q, Wang X, Yu Z, Wu X, Chen X, Li J, Zhu Z, Liu B, Su L
Oncogene 2017 Mar 30;36(13):1873-1886
Oncogene 2017 Mar 30;36(13):1873-1886
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Wang Y, Wu N, Sun D, Sun H, Tong D, Liu D, Pang B, Li S, Wei J, Dai J, Liu Y, Bai J, Geng J, Fu S, Jin Y
Cancer science 2017 Jun;108(6):1169-1176
Cancer science 2017 Jun;108(6):1169-1176
Downregulation of Bmi-1 suppresses epithelial‑mesenchymal transition in melanoma.
Liu Y, Chu Z, Li Q, Peng B, Xu S, Lian CG, Geng S
Oncology reports 2017 Jan;37(1):139-146
Oncology reports 2017 Jan;37(1):139-146
Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines.
Zhang Y, Zhang X, Huang J, Dong Q
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Medical oncology (Northwood, London, England) 2015 May;32(5):157
Helicobacter pylori dwelling on the apical surface of gastrointestinal epithelium damages the mucosal barrier through direct contact.
Zhang C, Zhang H, Yu L, Cao Y
Helicobacter 2014 Oct;19(5):330-42
Helicobacter 2014 Oct;19(5):330-42
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse uterus tissue were subjected to SDS PAGE followed by western blot with 12831-1-AP( CTNNA1 Antibody) at dilution of 1:2000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of A431 cells using 12831-1-AP( CTNNA1 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Alpha E catenin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Alpha E catenin. This antibody recognizes human,mouse,rat antigen. The Alpha E catenin antibody has been validated for the following applications: ELISA, WB, IHC, IF, FC analysis.
