orb385946

antibody from Biorbyt
Targeting: CTNNA1 CAP102
Provider product page for orb385946
Western blot
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb385946 - Provider product page
Provider
Biorbyt
Product name
Alpha Catenin Antibody
Antibody type
Monoclonal
Description
Recognizes a protein of 102kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-Catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-Catenin forms a heterodimer with beta-Catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-Catenin also regulates the beta-Catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
1G5
Vial size
20 ug
Storage
Store the Alpha Catenin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
CTNNA1 protein structure - orb385946 shown in red.