AP51124PU-N

antibody from Acris Antibodies GmbH

Targeting: CTNNB1 armadillo, beta-catenin, CTNNB

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

AP51124PU-N

Provider

Acris Antibodies GmbH

Proper citation

Product name

anti Catenin beta-1 (C-term)

Antibody type

Polyclonal

Antigen

KLH conjugated synthetic peptide between 653-681 amino acids from the C-terminal region of Human Catenin beta-1.

Reactivity

Human

Host

Rabbit

Vial size

0.4 ml

Concentration

lot specific

References

Submitted references

Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling.

Chairoungdua A, Smith DL, Pochard P, Hull M, Caplan MJ
The Journal of cell biology 2010 Sep 20;190(6):1079-91

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Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription.

Huang W, Zhou W, Saberwal G, Konieczna I, Horvath E, Katsoulidis E, Platanias LC, Eklund EA
Molecular and cellular biology 2010 Oct;30(19):4575-94

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NGX6 inhibits cell invasion and adhesion through suppression of Wnt/beta-catenin signal pathway in colon cancer.

Guo Q, Shen S, Liao M, Lian P, Wang X
Acta biochimica et biophysica Sinica 2010 Jul;42(7):450-6

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FoxM1 regulates re-annealing of endothelial adherens junctions through transcriptional control of beta-catenin expression.

Mirza MK, Sun Y, Zhao YD, Potula HH, Frey RS, Vogel SM, Malik AB, Zhao YY
The Journal of experimental medicine 2010 Aug 2;207(8):1675-85

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[Effect of siRNA-mediated beta-catenin gene on Wnt signal pathway in lung adenocarcinoma A549 cell].

Teng Y, Wang XW, Wang YW, Wang J
Zhonghua yi xue za zhi 2010 Apr 13;90(14):988-92

Western blot

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Western blot analysis of CTNB1 (arrow) using Catenin beta-1 Antibody (C-term) Cat.-No AP51124PU-N. 293 cell lysates (2 ug/lane) either non-transfected (Lane 1) or transiently transfected (Lane 2) with the CTNB1 gene.

Immunocytochemistry

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Confocal immunofluorescent analysis of Catenin beta-1 Antibody (C-term) Cat.-No AP51124PU-N with 293 cell followed by Alexa Fluor 488-conjugated Goat anti-Rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Immunohistochemistry

Supportive validation

Submitted by

Acris Antibodies GmbH (provider)

Main image

Experimental details

Formalin fixed, paraffin embedded human stomach tissuem stained with Catenin beta-1 Antibody (C-term) Cat.-No AP51124PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CTNB1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.